n-Pentyl sulfonyl chloride - PMC

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Items: 15

Select item 96580601.

Cannabinol: History, Syntheses, and Biological Profile of the Greatest “Minor” Cannabinoid

Chiara Maioli, Daiana Mattoteia, Hawraz Ibrahim M. Amin, Alberto Minassi, Diego Caprioglio

Plants (Basel) 2022 Nov; 11(21): 2896. Published online 2022 Oct 28. doi: 10.3390/plants11212896

PMCID:: PMC9658060

Abstract Article PDF–2.7M

Select item 113937342.

Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells

Vincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien Fortin

RSC Med Chem. 2024 Aug 27 doi: 10.1039/d4md00476k [Epub ahead of print]

PMCID:: PMC11393734

Abstract Article

Select item 77646873.

Recent Advances in the Synthesis of Selenophenes and Their Derivatives

Paola S. Hellwig, Thiago J. Peglow, Filipe Penteado, Luana Bagnoli, Gelson Perin, Eder J. Lenardão

Molecules. 2020 Dec; 25(24): 5907. Published online 2020 Dec 13. doi: 10.3390/molecules25245907

PMCID:: PMC7764687

Abstract Article PDF–50M

Select item 89920174.

Structure-Activity Relationship Studies to Identify Affinity Probes in Bis-aryl Sulfonamides that Prolong Immune Stimuli

Michael Chan, Fitzgerald S Lao, Paul J. Chu, Jonathan Shpigelman, Shiyin Yao, Jason Nan, Fumi Sato-Kaneko, Vicky Li, Tomoko Hayashi, Maripat Corr, Dennis A. Carson, Howard B. Cottam, Nikunj M. Shukla

J Med Chem. Author manuscript; available in PMC 2022 Apr 8.

Published in final edited form as: J Med Chem. 2019 Nov 14; 62(21): 9521–9540. Published online 2019 Oct 25. doi: 10.1021/acs.jmedchem.9b00870

PMCID:: PMC8992017

Abstract Article PDF–2.2M

Select item 34657295.

HIV-1 Protease Inhibitors from Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant Variants

Michael D. Altman, Akbar Ali, G. S. Kiran Kumar Reddy, Madhavi N. L. Nalam, Saima Ghafoor Anjum, Hong Cao, Sripriya Chellappan, Visvaldas Kairys, Miguel X. Fernandes, Michael K. Gilson, Celia A. Schiffer, Tariq M. Rana, Bruce Tidor

J Am Chem Soc. Author manuscript; available in PMC 2012 Oct 8.

Published in final edited form as: J Am Chem Soc. 2008 May 14; 130(19): 6099–6113. Published online 2008 Apr 16. doi: 10.1021/ja076558p

PMCID:: PMC3465729

Abstract Article PDF–3.5M

Select item 110422446.

Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity

Letizia Crocetti, Francesca Catarzi, Maria Paola Giovannoni, Claudia Vergelli, Gianluca Bartolucci, Marco Pallecchi, Paola Paoli, Patrizia Rossi, Martina Lippi, Igor A. Schepetkin, Mark T. Quinn, Gabriella Guerrini

RSC Med Chem. 2024 Apr 24; 15(4): 1247–1257. Published online 2024 Mar 19. doi: 10.1039/d3md00736g

PMCID:: PMC11042244

Abstract Article PDF–751K

Select item 86133587.

Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design

Ganyuan Xiao, Magnus S. Alphey, Fanny Tran, Lisa Pirrie, Pierre Milbeo, Yi Zhou, Jasmine K. Bickel, Oxana Kempf, Karl Kempf, James H. Naismith, Nicholas J. Westwood

Bioorg Med Chem. 2021 Nov 15; 50: 116477. doi: 10.1016/j.bmc.2021.116477

PMCID:: PMC8613358

Abstract Article PDF–5.3M

Select item 51874978.

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units

Lauren Ray, Timothy R. Valentic, Takeshi Miyazawa, David M. Withall, Lijiang Song, Jacob C. Milligan, Hiroyuki Osada, Shunji Takahashi, Shiou-Chuan Tsai, Gregory L. Challis

Nat Commun. 2016; 7: 13609. Published online 2016 Dec 21. doi: 10.1038/ncomms13609

PMCID:: PMC5187497

Abstract Article PDF–1.1M

Select item 63321979.

Design, Synthesis and Bioactivities of Novel Dichloro-Allyloxy-Phenol-Containing Pyrazole Oxime Derivatives

Hong Dai, Linyu Ye, Huiyang Zhuang, Baojiang Dai, Yuan Fang, Yujun Shi

Molecules. 2015 Dec; 20(12): 21870–21880. Published online 2015 Dec 8. doi: 10.3390/molecules201219811

PMCID:: PMC6332197

Abstract Article PDF–556K

Select item 1144049710.

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Anirban Ghoshal, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Meganathan Nandakumar, Anand Vala, Eric M. Merten, John D. Sears, Isabella Law, Jane E. Burdick, Noah L. Morales, Sumera Perveen, Kenneth H. Pearce, Konstantin I. Popov, Nathaniel J. Moorman, Mark T. Heise, Timothy M. Willson

J Med Chem. 2024 Sep 26; 67(18): 16505–16532. Published online 2024 Sep 5. doi: 10.1021/acs.jmedchem.4c01346

PMCID:: PMC11440497

Abstract Article PDF–3.5M

Select item 1119526411.

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity

Anirban Ghoshal, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Eric M. Merten, John D. Sears, Sumera Perveen, Kenneth H. Pearce, Konstantin I. Popov, Nathaniel J. Moorman, Mark T. Heise, Timothy M. Willson

Version 2. bioRxiv. Preprint. 2024 Jun 13. doi: 10.1101/2024.06.12.598722

Published in:: J Med Chem. 2024 Sep 26; 67(18): 16505–16532.

PMCID:: PMC11195264

Abstract Article PDF–1.6M

Select item 629922012.

Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA

Pradeep Kumar, Glenn C. Capodagli, Divya Awasthi, Riju Shrestha, Karishma Maharaja, Paridhi Sukheja, Shao-Gang Li, Daigo Inoyama, Matthew Zimmerman, Hsin Pin Ho Liang, Jansy Sarathy, Marizel Mina, George Rasic, Riccardo Russo, Alexander L. Perryman, Todd Richmann, Aditi Gupta, Eric Singleton, Sheetal Verma, Seema Husain, Patricia Soteropoulos, Zhe Wang, Roxanne Morris, Gene Porter, Gautam Agnihotri, Padmini Salgame, Sean Ekins, Kyu Y. Rhee, Nancy Connell, Véronique Dartois, Matthew B. Neiditch, Joel S. Freundlich, David Alland

mBio. 2018 Nov-Dec; 9(6): e02101-17. Published online 2018 Dec 18. doi: 10.1128/mBio.02101-17

PMCID:: PMC6299220

Abstract Article PDF–4.7M

Select item 1071858413.

Synthesis, biological and molecular modelling for 1,3,4-thiadiazole sulfonyl thioureas: bacterial and fungal activity

Nguyen Dinh Thanh, Vu Ngoc Toan, Nguyen Thi Kim Giang, Hoang Thi Kim Van, Do Son Hai, Nguyen Minh Tri, Duong Ngoc Toan

RSC Med Chem. 2023 Dec 13; 14(12): 2751–2767. Published online 2023 Oct 25. doi: 10.1039/d3md00508a

PMCID:: PMC10718584

Abstract Article PDF–4.4M

Select item 992384214.

Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I)

Atsuhito Tsuji, Takahiro Masuya, Norihito Arichi, Shinsuke Inuki, Masatoshi Murai, Hideto Miyoshi, Hiroaki Ohno

ACS Med Chem Lett. 2023 Feb 9; 14(2): 211–216. Published online 2023 Jan 24. doi: 10.1021/acsmedchemlett.2c00504

PMCID:: PMC9923842

Abstract Article PDF–2.5M

Select item 562900315.

The Synthesis and Structures of 1,1′-Bis(sulfonyl)ferrocene Derivatives

Kullapa Chanawanno, Cole Holstrom, Laura A. Crandall, Henry Dodge, Victor N. Nemykin, Richard S. Herrick, Christopher J. Ziegler

Dalton Trans. Author manuscript; available in PMC 2017 Oct 5.

Published in final edited form as: Dalton Trans. 2016 Sep 28; 45(36): 14320–14326. Published online 2016 Aug 19. doi: 10.1039/c6dt02669a

PMCID:: PMC5629003

Abstract Article PDF–559K

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