deiodinase-2 - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 1058

<< First< Prev

Page of 53

Next >Last >>

Select item 86928821.

Region-specific effects of antenatal/early postnatal hypothyroidism on endothelial NO-pathway activity in systemic circulation

Dina K. Gaynullina, Svetlana I. Sofronova, Ekaterina K. Selivanova, Anastasia A. Shvetsova, Anna A. Borzykh, Olga S. Tarasova

Curr Res Physiol. 2022; 5: 8–15. Published online 2021 Dec 14. doi: 10.1016/j.crphys.2021.12.002

PMCID:: PMC8692882

Abstract Article PDF–2.3M

Select item 90657812.

Identification of polymorphic loci in the deiodinase 2 gene and their associations with head dimensions in geese

Yan Deng, Qian Hu, Bincheng Tang, Qingyuan Ouyang, Shenqiang Hu, Bo Hu, Jiwei Hu, Hua He, Guohong Chen, Jiwen Wang

Anim Biosci. 2022 May; 35(5): 639–647. Published online 2021 Oct 29. doi: 10.5713/ab.21.0382

PMCID:: PMC9065781

Abstract Article PDF–1.2M

Select item 39782563.

Thyroid Hormones, T3 and T4, in the Brain

Amy C. Schroeder, Martin L. Privalsky

Front Endocrinol (Lausanne) 2014; 5: 40. Published online 2014 Mar 31. doi: 10.3389/fendo.2014.00040

PMCID:: PMC3978256

Abstract Article PDF–707K

Select item 66761034.

Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc^Δ716 mutant mice

Yasushi Kojima, Yuriko Kondo, Teruaki Fujishita, Emi Mishiro‐Sato, Rie Kajino‐Sakamoto, Makoto Mark Taketo, Masahiro Aoki

Cancer Sci. 2019 Aug; 110(8): 2520–2528. Published online 2019 Jul 7. doi: 10.1111/cas.14100

PMCID:: PMC6676103

Abstract Article PDF–1.6M

Select item 106971725.

Diabetes Modulates Iodothyronine Deiodinase 2 Expression in the Mouse Retina: A Role for Thyroid Hormone in the Pathogenesis of Diabetic Retinopathy

Reena Bapputty, Hima Sapa, Miyagi Masaru, Rose A. Gubitosi-Klug

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 3. Published online 2023 Dec 1. doi: 10.1167/iovs.64.15.3

PMCID:: PMC10697172

Abstract Article PDF–4.3M

Select item 36428496.

Using Whole mount In Situ Hybridization to Examine Thyroid Hormone Deiodinase Expression in Embryonic and Larval Zebrafish: a Tool for examining OH-BDE toxicity to early life stages

Wu Dong, Laura Macaulay, Kevin WH Kwok, David E Hinton, Heather M. Stapleton

Aquat Toxicol. Author manuscript; available in PMC 2014 May 15.

Published in final edited form as: Aquat Toxicol. 2013 May 15; 0: 190–199. Published online 2013 Mar 4. doi: 10.1016/j.aquatox.2013.02.008

PMCID:: PMC3642849

Abstract Article PDF–2.2M

Select item 89520167.

Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats

Antonia Giacco, Federica Cioffi, Arianna Cuomo, Roberta Simiele, Rosalba Senese, Elena Silvestri, Angela Amoresano, Carolina Fontanarosa, Giuseppe Petito, Maria Moreno, Antonia Lanni, Assunta Lombardi, Pieter de Lange

Nutrients. 2022 Mar; 14(6): 1166. Published online 2022 Mar 10. doi: 10.3390/nu14061166

PMCID:: PMC8952016

Abstract Article PDF–2.4M

Select item 115082468.

Seasonal changes in activity of hypothalamic thyroid hormone system in different winter phenotypes of Djungarian hamster (Phodopus sungorus)

Anna S. Przybylska-Piech, Victoria Diedrich, Annika Herwig

PLoS One. 2024; 19(10): e0309591. Published online 2024 Oct 25. doi: 10.1371/journal.pone.0309591

PMCID:: PMC11508246

Abstract Article PDF–2.2M

Select item 111677509.

A DIO2 missense mutation and its impact on fetal response to PRRSV infection

Haesu Ko, J. Alex Pasternak, Margaret K. Mulligan, Glenn Hamonic, Naresh Ramesh, Daniel J. MacPhee, Graham S. Plastow, John C. S. Harding

BMC Vet Res. 2024; 20: 255. Published online 2024 Jun 12. doi: 10.1186/s12917-024-04099-4

PMCID:: PMC11167750

Abstract Article PDF–2.7M

Select item 662474910.

Limited Support for Thyroid Hormone or Corticosterone Related Gene Expression as a Proximate Mechanism of Incubation Temperature-Dependent Phenotypes in Birds

Sydney F. Hope, Christopher R. Buenaventura, Zahabiya Husain, Sarah E. DuRant, Robert A. Kennamer, William A. Hopkins, Christopher K. Thompson

Front Physiol. 2019; 10: 857. Published online 2019 Jul 5. doi: 10.3389/fphys.2019.00857

PMCID:: PMC6624749

Abstract Article PDF–756K

Select item 768548211.

High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus

Sebastián Gutiérrez-Vega, Axel Armella, Daniela Mennickent, Marco Loyola, Ambart Covarrubias, Bernel Ortega-Contreras, Carlos Escudero, Marcelo Gonzalez, Martín Alcalá, María del Pilar Ramos, Marta Viana, Erica Castro, Andrea Leiva, Enrique Guzmán-Gutiérrez

PLoS One. 2020; 15(11): e0242743. Published online 2020 Nov 24. doi: 10.1371/journal.pone.0242743

PMCID:: PMC7685482

Abstract Article PDF–1.4M

Select item 1083862012.

Transcriptomic analyses and machine-learning methods reveal dysregulated key genes and potential pathogenesis in human osteoarthritic cartilage

Di Zhao, Ling-feng Zeng, Gui-hong Liang, Ming-hui Luo, Jian-ke Pan, Yao-xing Dou, Fang-zheng Lin, He-tao Huang, Wei-yi Yang, Jun Liu

Bone Joint Res. 2024 Feb; 13(2): 66–82. Published online 2024 Feb 5. doi: 10.1302/2046-3758.132.BJR-2023-0074.R1

PMCID:: PMC10838620

Abstract Article PDF–9.6M

Select item 1093338713.

Effects of Empagliflozin‐Induced Glycosuria on Weight Gain, Food Intake and Metabolic Indicators in Mice Fed a High‐Fat Diet

Anh T. Nguyen, Zachary Amigo, Kathleen McDuffie, Victoria C. MacQueen, Lane D. Bell, Lan K. Truong, Gloria Batchi, Sara M. McMillin

Endocrinol Diabetes Metab. 2024 Mar; 7(2): e00475. Published online 2024 Mar 12. doi: 10.1002/edm2.475

PMCID:: PMC10933387

Abstract Article PDF–1002K

Select item 609586814.

A thyroid hormone regulated asymmetric responsive centre is correlated with eye migration during flatfish metamorphosis

Marco A. Campinho, Nádia Silva, Gabriel G. Martins, Liliana Anjos, Claudia Florindo, Javier Roman-Padilla, Ana Garcia-Cegarra, Bruno Louro, Manuel Manchado, Deborah M. Power

Sci Rep. 2018; 8: 12267. Published online 2018 Aug 16. doi: 10.1038/s41598-018-29957-8

PMCID:: PMC6095868

Abstract Article PDF–4.0M

Select item 529774915.

Transthyretin: A Transporter Protein Essential for Proliferation of Myoblast in the Myogenic Program

Eun Ju Lee, Smritee Pokharel, Arif Tasleem Jan, Soyeon Huh, Richelle Galope, Jeong Ho Lim, Dong-Mok Lee, Sung Wook Choi, Sang-Soep Nahm, Yong-Woon Kim, So-Young Park, Inho Choi

Int J Mol Sci. 2017 Jan; 18(1): 115. Published online 2017 Jan 8. doi: 10.3390/ijms18010115

PMCID:: PMC5297749

Abstract Article PDF–9.9M

Select item 304747516.

Zebrafish (Danio rerio) vary by strain and sex in their behavioral and transcriptional responses to selenium supplementation

Maia J. Benner, Robert E. Drew, Ronald W. Hardy, Barrie D. Robison

Comp Biochem Physiol A Mol Integr Physiol. Author manuscript; available in PMC 2011 Mar 2.

Published in final edited form as: Comp Biochem Physiol A Mol Integr Physiol. 2010 Dec; 157(4): 310–318. Published online 2010 Jul 24. doi: 10.1016/j.cbpa.2010.07.016

PMCID:: PMC3047475

Abstract Article PDF–1.0M

Select item 320032217.

A Component of Retinal Light Adaptation Mediated by the Thyroid Hormone Cascade

Diana E. Bedolla, Vincent Torre

PLoS One. 2011; 6(10): e26334. Published online 2011 Oct 24. doi: 10.1371/journal.pone.0026334

PMCID:: PMC3200322

Abstract Article PDF–969K

Select item 1068763118.

Designing a combined liothyronine (LT3), L- thyroxine (LT4) trial in symptomatic hypothyroid subjects on LT4 - the importance of patient selection, choice of LT3 and trial design

Lakdasa D. Premawardhana, Peter Nicholas Taylor, Onyebuchi E. Okosieme, Mohamed A. Adlan, Emmanuel K. Obuobie, Colin Mark Dayan

Front Endocrinol (Lausanne) 2023; 14: 1282608. Published online 2023 Nov 16. doi: 10.3389/fendo.2023.1282608

PMCID:: PMC10687631

Abstract Article PDF–656K

Select item 781132319.

Molecular economy of nature with two thyrotropins from different parts of the pituitary: pars tuberalis thyroid-stimulating hormone and pars distalis thyroid-stimulating hormone

Sibel Ertek

Arch Med Sci. 2021; 17(1): 189–195. Published online 2021 Jan 5. doi: 10.5114/aoms/102476

PMCID:: PMC7811323

Abstract Article PDF–87K

Select item 962300920.

Interaction between the hypothalamo-pituitary-adrenal and thyroid axes during immobilization stress

Hakeem J. Kadhim, Wayne J. Kuenzel

Front Physiol. 2022; 13: 972171. Published online 2022 Oct 18. doi: 10.3389/fphys.2022.972171

PMCID:: PMC9623009

Abstract Article PDF–1.1M

<< First< Prev

Page of 53

Next >Last >>

Supplemental Content

Filter your results:

Manage Filters

PMC Images search for deiodinase-2

Figure 3

Confirmation of the four polymorphic loci of the deiodinase 2 gene in the population of Tianfu meat geese. The black boxes represented the polymorphic loci. The first and second rows were homozygotes, and the third row was heterozygote.

Identification of polymorphic loci in the deiodinase 2 gene and their associations with head dimensions in geese

Anim Biosci. 2022 May;35(5):639-647.
Figure 2

Comparison analysis of the deiodinase 2 gene coding sequences between Sichuan White geese and Landes geese. The top row represented Landes geese, the bottom row represented Sichuan White geese. * Indicated the consistent nucleotides, locations at 419, 533, 725, 799 indicated the inconsistent nucleotides. The number on the left represented the position of nucleotides.

Identification of polymorphic loci in the deiodinase 2 gene and their associations with head dimensions in geese

Anim Biosci. 2022 May;35(5):639-647.
Figure 3

Schematic overview of deiodinase isoforms reactions. DIO1: deiodinase 1; DIO2: deiodinase 2; DIO3: deiodinase 3.

Selenoproteins in Health

Molecules. 2024 Jan;29(1):136.
Fig. 1

Putative effects of nicotine on thyroid signaling through astrocytes. Nicotine binds to nAChRs on astrocytes to stimulate deiodinase 2 (D2) activity. Deiodinase 2 converts T₄ to T₃ in astrocytes and active thyroid hormone passively diffuses to nearby neurons. T₃ binds to receptors in the nucleus of target neurons where it acts to regulate gene transcription activity. Thyroid hormone transporters with higher affinity for T₄ (OATP1C1) and T₃ (MCT8) are included on astrocytes and neurons, respectively.

Thyroid hormone signaling: Contribution to neural function, cognition, and relationship to nicotine

Neurosci Biobehav Rev. ;57:252-263.