class IIa beta-tubulin - PMC

Margareta Pernar Kovač, Vanja Tadić, Juran Kralj, George E. Duran, Alessia Stefanelli, Darija Stupin Polančec, Sanja Dabelić, Niko Bačić, Maja T. Tomicic, Petra Heffeter, Branimir I. Sikic, Anamaria Brozovic

Cell Mol Life Sci. 2023 Oct; 80(10): 294. Published online 2023 Sep 17. doi: 10.1007/s00018-023-04943-0

PMCID:: PMC11071939

Abstract Article PDF–8.5M

Select item 101657694.

Microtubule acetylation dyshomeostasis in Parkinson’s disease

Padmashri Naren, Khan Sabiya Samim, Kamatham Pushpa Tryphena, Lalitkumar K. Vora, Saurabh Srivastava, Shashi Bala Singh, Dharmendra Kumar Khatri

Transl Neurodegener. 2023; 12: 20. Published online 2023 May 8. doi: 10.1186/s40035-023-00354-0

PMCID:: PMC10165769

Abstract Article PDF–4.3M

Select item 113207565.

Role of tubulin post-translational modifications in peripheral neuropathy

Maria Elena Pero, Farihah Chowdhury, Francesca Bartolini

Exp Neurol. Author manuscript; available in PMC 2024 Aug 13.

Published in final edited form as: Exp Neurol. 2023 Feb; 360: 114274. Published online 2022 Nov 13. doi: 10.1016/j.expneurol.2022.114274

PMCID:: PMC11320756

Abstract Article PDF–1.9M

Select item 74645206.

Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells

Filip Borys, Ewa Joachimiak, Hanna Krawczyk, Hanna Fabczak

Molecules. 2020 Aug; 25(16): 3705. Published online 2020 Aug 14. doi: 10.3390/molecules25163705

PMCID:: PMC7464520

Abstract Article PDF–4.6M

Select item 68131707.

Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition

Christine M. Lee, Nicole R. Zane, Gareth Veal, Dhiren R. Thakker

CPT Pharmacometrics Syst Pharmacol. 2019 Oct; 8(10): 759–768. Published online 2019 Aug 30. doi: 10.1002/psp4.12453

PMCID:: PMC6813170

Abstract Article PDF–602K

Select item 36646658.

Regulatory Polymorphisms in β-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy

Luis J. Leandro-García, Susanna Leskelä, Carlos Jara, Henrik Gréen, Elisabeth Åvall-Lundqvist, Heather E. Wheeler, M. Eileen Dolan, Lucia Inglada-Perez, Agnieszka Maliszewska, Aguirre A. de Cubas, Iñaki Comino-Méndez, Veronika Mancikova, Alberto Cascón, Mercedes Robledo, Cristina Rodríguez-Antona

Clin Cancer Res. Author manuscript; available in PMC 2013 May 27.

Published in final edited form as: Clin Cancer Res. 2012 Aug 15; 18(16): 4441–4448. Published online 2012 Jun 20. doi: 10.1158/1078-0432.CCR-12-1221

PMCID:: PMC3664665

Abstract Article PDF–911K

Select item 105987959.

Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach

Mark James Horgan, Lukas Zell, Bianka Siewert, Hermann Stuppner, Daniela Schuster, Veronika Temml

J Chem Inf Model. 2023 Oct 23; 63(20): 6396–6411. Published online 2023 Sep 29. doi: 10.1021/acs.jcim.3c00939

PMCID:: PMC10598795

Abstract Article PDF–9.0M

Select item 958142510.

Understanding molecular mechanisms and predicting phenotypic effects of pathogenic tubulin mutations

Thomas J. Attard, Julie P. I. Welburn, Joseph A. Marsh

PLoS Comput Biol. 2022 Oct; 18(10): e1010611. Published online 2022 Oct 7. doi: 10.1371/journal.pcbi.1010611

PMCID:: PMC9581425

Abstract Article PDF–2.4M

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Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics

James Mark Wagstaff, Vicente José Planelles-Herrero, Grigory Sharov, Aisha Alnami, Frank Kozielski, Emmanuel Derivery, Jan Löwe

Sci Adv. 2023 Mar; 9(13): eadf3021. Published online 2023 Mar 29. doi: 10.1126/sciadv.adf3021

PMCID:: PMC10058229

Abstract Article PDF–1.2M

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Prognostic Biomarkers for HNSCC using Quantitative Real-Time PCR and Microarray Analysis: β-Tubulin Isotypes and the p53 Interactome

Sharon Lobert, Mary E. Graichen, Robert D. Hamilton, Karen T. Pitman, Michael R. Garrett, Chindo Hicks, Tejaswi Koganti

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2015 Nov 22.

Published in final edited form as: Cytoskeleton (Hoboken). 2014 Nov; 71(11): 628–637. Published online 2014 Nov 22. doi: 10.1002/cm.21195

PMCID:: PMC4367444

Abstract Article PDF–1.0M

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Rationalization of paclitaxel insensitivity of yeast β-tubulin and human βIII-tubulin isotype using principal component analysis

Lalita Das, Bhabatarak Bhattacharya, Gautam Basu

BMC Res Notes. 2012; 5: 395. Published online 2012 Aug 1. doi: 10.1186/1756-0500-5-395

PMCID:: PMC3477043

Abstract Article PDF–1.8M

Select item 1128572714.

A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease

Haonan Liu, Julie P. I. Welburn

Open Biol. 2024 Jun; 14(6): 240041. Published online June 5, 2024. doi: 10.1098/rsob.240041

PMCID:: PMC11285727

Abstract Article PDF–1.1M

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The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation

Kseniya Ustinova, Zora Novakova, Makoto Saito, Marat Meleshin, Jana Mikesova, Zsofia Kutil, Petra Baranova, Barbora Havlinova, Mike Schutkowski, Patrick Matthias, Cyril Barinka

J Biol Chem. 2020 Feb 28; 295(9): 2614–2628. Published online 2020 Jan 17. doi: 10.1074/jbc.RA119.011243

PMCID:: PMC7049964

Abstract Article PDF–3.1M

Select item 611615316.

Genetics and Expression Profile of the Tubulin Gene Superfamily in Breast Cancer Subtypes and Its Relation to Taxane Resistance

Babak Nami, Zhixiang Wang

Cancers (Basel) 2018 Aug; 10(8): 274. Published online 2018 Aug 18. doi: 10.3390/cancers10080274

PMCID:: PMC6116153

Abstract Article PDF–3.0M

Select item 1110568617.

ATAT1 regulates forebrain development and stress-induced tubulin hyperacetylation

Lin Li, Sriram Jayabal, Mohammad Ghorbani, Lisa-Marie Legault, Serge McGraw, Alanna J. Watt, Xiang-Jiao Yang

Cell Mol Life Sci. 2019 Sep; 76(18): 3621–3640. Published online 2019 Apr 5. doi: 10.1007/s00018-019-03088-3

PMCID:: PMC11105686

Abstract Article PDF–3.4M

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Pathogenic role of delta 2 tubulin in bortezomib-induced peripheral neuropathy

Maria Elena Pero, Cristina Meregalli, Xiaoyi Qu, Grace Ji-eun Shin, Atul Kumar, Matthew Shorey, Melissa M. Rolls, Kurenai Tanji, Thomas H. Brannagan, Paola Alberti, Giulia Fumagalli, Laura Monza, Wesley B. Grueber, Guido Cavaletti, Francesca Bartolini

Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2012685118. Published online 2021 Jan 19. doi: 10.1073/pnas.2012685118

Correction in:: Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2115637118.

PMCID:: PMC7848563

Abstract Article PDF–3.2M

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De Novo Mutations in the Beta-Tubulin Gene TUBB2A Cause Simplified Gyral Patterning and Infantile-Onset Epilepsy

Thomas D. Cushion, Alex R. Paciorkowski, Daniela T. Pilz, Jonathan G.L. Mullins, Laurie E. Seltzer, Robert W. Marion, Emily Tuttle, Dalia Ghoneim, Susan L. Christian, Seo-Kyung Chung, Mark I. Rees, William B. Dobyns

Am J Hum Genet. 2014 Apr 3; 94(4): 634–641. doi: 10.1016/j.ajhg.2014.03.009

PMCID:: PMC3980418

Abstract Article PDF–2.4M

Select item 652398620.

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

Anastasiya Klebanovych, Vladimíra Sládková, Tetyana Sulimenko, Věra Vosecká, Zuzana Rubíková, Martin Čapek, Eduarda Dráberová, Pavel Dráber, Vadym Sulimenko

Cells. 2019 Apr; 8(4): 345. Published online 2019 Apr 11. doi: 10.3390/cells8040345