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Select item 113119551.

Pirfenidone Alleviates Inflammation and Fibrosis of Acute Respiratory Distress Syndrome by Modulating the Transforming Growth Factor-β/Smad Signaling Pathway

Seung Sook Paik, Jeong Mi Lee, Il-Gyu Ko, Sae Rom Kim, Sung Wook Kang, Jin An, Jin Ah Kim, Dongyon Kim, Lakkyong Hwang, Jun-Jang Jin, Sang-Hoon Kim, Jun-Youl Cha, Cheon Woong Choi

Int J Mol Sci. 2024 Aug; 25(15): 8014. Published online 2024 Jul 23. doi: 10.3390/ijms25158014

PMCID:: PMC11311955

Abstract Article PDF–4.8M

Select item 113646152.

Search for new steroidal glycosides with anti-cancer potential from natural resources

Yukiko Matsuo, Yoshihiro Mimaki

J Nat Med. 2024; 78(4): 807–827. Published online 2024 Jul 17. doi: 10.1007/s11418-024-01830-1

PMCID:: PMC11364615

Abstract Article PDF–3.5M

Select item 111241853.

Effects of Saponins on Lipid Metabolism: The Gut–Liver Axis Plays a Key Role

Shixi Cao, Mengqi Liu, Yao Han, Shouren Li, Xiaoyan Zhu, Defeng Li, Yinghua Shi, Boshuai Liu

Nutrients. 2024 May; 16(10): 1514. Published online 2024 May 17. doi: 10.3390/nu16101514

PMCID:: PMC11124185

Abstract Article PDF–2.1M

Select item 111063734.

Advancements and challenges in pharmacokinetic and pharmacodynamic research on the traditional Chinese medicine saponins: a comprehensive review

Yuhan Ma, Yongxia Zhao, Mingxia Luo, Qin Jiang, Sha Liu, Qi Jia, Zhixun Bai, Faming Wu, Jian Xie

Front Pharmacol. 2024; 15: 1393409. Published online 2024 May 7. doi: 10.3389/fphar.2024.1393409

PMCID:: PMC11106373

Abstract Article PDF–1.8M

Select item 110442625.

Fabrication, Characterization, and Biological Evaluation of T. terrestris Incorporated Titanium-Doped ZnO/Cellulose Nanocomposite Films as a Therapeutic Hemostatic Scaffolds for Diabetic Wound Healing

Jijo Thomas Koshy, Dhanaraj Sangeetha, Yogesh Bele, Murugan Rakshitha

ACS Omega. 2024 Apr 23; 9(16): 18327–18340. Published online 2024 Apr 9. doi: 10.1021/acsomega.4c00174

PMCID:: PMC11044262

Abstract Article PDF–3.8M

Select item 108753866.

Promising phytopharmacology, nutritional potential, health benefits, and traditional usage of Tribulus terrestris L. herb

Muhammad Saeed, Mahzaib Munawar, Jannat Bi Bi, Shabbir Ahmed, Muhammad Zia Ahmad, Asghar Ali Kamboh, Muhammad Asif Arain, Muhammad Naveed, Huayou Chen

Heliyon. 2024 Feb 29; 10(4): e25549. Published online 2024 Jan 30. doi: 10.1016/j.heliyon.2024.e25549

PMCID:: PMC10875386

Abstract Article PDF–5.4M

Select item 106988317.

Pro‐inflammatory cytokine IL‐6 regulates LMO4 expression in psoriatic keratinocytes via AKT/STAT3 pathway

Zhenzhen Tu, Wei Wei, Qiantong Xiang, Wenwen Wang, Siping Zhang, Haisheng Zhou

Immun Inflamm Dis. 2023 Dec; 11(12): e1104. Published online 2023 Dec 6. doi: 10.1002/iid3.1104

PMCID:: PMC10698831

Abstract Article PDF–2.5M

Select item 103989798.

A systematic review of the research progress of traditional Chinese medicine against pulmonary fibrosis: from a pharmacological perspective

Shanbo Qin, Peng Tan, Junjie Xie, Yongfeng Zhou, Junning Zhao

Chin Med. 2023; 18: 96. Published online 2023 Aug 3. doi: 10.1186/s13020-023-00797-7

PMCID:: PMC10398979

Abstract Article PDF–1.4M

Select item 104174659.

Steroidal Saponins: Naturally Occurring Compounds as Inhibitors of the Hallmarks of Cancer

Salwa Bouabdallah, Amna Al-Maktoum, Amr Amin

Cancers (Basel) 2023 Aug; 15(15): 3900. Published online 2023 Jul 31. doi: 10.3390/cancers15153900

PMCID:: PMC10417465

Abstract Article PDF–5.2M

Select item 1005234410.

Inhibiting Angiogenesis by Anti-Cancer Saponins: From Phytochemistry to Cellular Signaling Pathways

Mohammad Bagher Majnooni, Sajad Fakhri, Syed Mustafa Ghanadian, Gholamreza Bahrami, Kamran Mansouri, Amin Iranpanah, Mohammad Hosein Farzaei, Mahdi Mojarrab

Metabolites. 2023 Mar; 13(3): 323. Published online 2023 Feb 22. doi: 10.3390/metabo13030323

PMCID:: PMC10052344

Abstract Article PDF–2.6M

Select item 983152611.

Effects of Neuropeptides on Dendritic Cells in the Pathogenesis of Psoriasis

Jingya Zhang, Siqi Zhao, Xinzhu Xing, Lin Shang, Jiali Cao, Yanling He

J Inflamm Res. 2023; 16: 35–43. Published online 2023 Jan 6. doi: 10.2147/JIR.S397079

PMCID:: PMC9831526

Abstract Article PDF–2.4M

Select item 964331812.

Integrating transcriptomics and network analysis-based multiplexed drug repurposing to screen drug candidates for M2 macrophage-associated castration-resistant prostate cancer bone metastases

Jinyuan Chang, Zhenglong Jiang, Tianyu Ma, Jie Li, Jiayang Chen, Peizhi Ye, Li Feng

Front Immunol. 2022; 13: 989972. Published online 2022 Oct 26. doi: 10.3389/fimmu.2022.989972

PMCID:: PMC9643318

Abstract Article PDF–13M

Select item 917136313.

Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT₁ and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition

Qun Yu, Dewei Zhu, Yang Zou, Kai Wang, Peili Rao, Yunhui Shen

Front Med (Lausanne) 2022; 9: 878601. Published online 2022 May 24. doi: 10.3389/fmed.2022.878601

PMCID:: PMC9171363

Abstract Article PDF–15M

Select item 873082214.

Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications

Pulok K Mukherjee, Thomas Efferth, Bhaskar Das, Amit Kar, Suparna Ghosh, Seha Singha, Pradip Debnath, Nanaocha Sharma, Pardeep Kumar Bhardwaj, Pallab Kanti Haldar

Phytomedicine. 2022 Apr; 98: 153930. Published online 2022 Jan 5. doi: 10.1016/j.phymed.2022.153930

PMCID:: PMC8730822

Abstract Article PDF–4.4M

Select item 815072915.

Cymbopogon winterianus Essential Oil Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Murine Model

Lívia A. Tavares, Allan A. Rezende, Jymmys L. Santos, Charles S. Estevam, Ana M. O. Silva, Jaderson K. Schneider, John L. S. Cunha, Daniela Droppa-Almeida, Ivan J. Correia-Neto, Juliana C. Cardoso, Patricia Severino, Eliana B. Souto, Ricardo L. C. de Albuquerque-Júnior

Pharmaceutics. 2021 May; 13(5): 679. Published online 2021 May 9. doi: 10.3390/pharmaceutics13050679