PMC

Total phenolic content and antioxidant capacity results of cookies. R1S1:100% rice flour, 0% stevia; R1S2: 100% rice flour, 25% stevia; R1S3: 100% rice flour, 50% stevia; R2S1A1: 90% rice flour, 10% almond flour, 0% stevia; R2S2A1: 90% rice flour, 10% almond flour, 25% stevia; R2S3A1: 90% rice flour, 10% almond flour, 50% stevia; R3S1A2: 80% rice flour, 20% almond flour, 0% stevia; R3S2A2: 80% rice flour, 20% almond flour, 25% stevia; R3S3A2: 80% rice flour, 20% almond flour, 50% stevia; R4S1A3: 70% rice flour, 30% almond flour, 0% stevia; R4S2A3: 70% rice flour, 30% almond flour, 25% stevia; R4S3A3: 70% rice flour, 30% almond flour, 50% stevia

A. Male Wistar rats statistical analyses of serum insulin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. B. Female Wistar rats statistical analyses of serum insulin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. C. Male Wistar rats statistical analyses of serum glucagon data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. D. Female Wistar rats statistical analyses of serum glucagon data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. E. Male Wistar rats statistical analyses of serum leptin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. F. Female Wistar rats statistical analyses of serum leptin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. G. Male Wistar rats statistical analyses of serum ghrelin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. H. Female Wistar rats statistical analyses of serum ghrelin data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. I. Male Wistar rats statistical analyses of serum glucose dependent insulinotropic peptide, GIP, data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8. J. Female Wistar rats statistical analyses of serum glucose dependent insulinotropic peptide, GIP, data 120 days after weaning consuming stevia infusion, drinking water sweetened with glucose (control), and plain water (blank). Its CI is at 95%. The following letters indicate significant differences p<0.05: a, b, c, d. Games-Howell Method n = 8.

In-vitro DNA damage reversal in presence of Stevia. Lane 1—DNA (0.5 μg); Lane 2—DNA (0.5 μg) + Stevia (5 μg); Lane 3—DNA (0.5 μg) + Lys (20 mM) + MG (20 mM); Lane 4—DNA (0.5 μg) + Lys (20 mM) + MG (20 mM) + Stevia (1 mg/mL); Lane 5—DNA (0.5 μg) + Lys (20 mM) + MG (20 mM) + Stevia (0.5 mg/mL); and Lane 6—DNA (0.5 μg) + Lys (20 mM) + MG (20 mM) +Stevia (0.1 mg/mL).

Plant regeneration and extraction of harvested leaf.
Notes: (A) Callus induction from stevia leaf with 2,4-D. (B) Shoot formation from callus with MS + BAP. (C) Stevia plant growing in the field. (D) Harvested stevia leaf from field. (E) Extraction from stevia leaf