Preparation of H. cordata Thunb. extracts and solvent-partitioned extraction technique. The diagram represents the flow chart of ethanolic extraction and the solvent-partition method to obtain the ethanolic extract and the concentrated fractions of H. cordata, including, H. cordata ethanolic extract (HcEE), H. cordata dichloromethane fraction (HcDM), H. cordata ethyl acetate fraction (HcEA), and H. cordata water fraction (Hc-H2O). EtOH: ethanol, DI H2O: deionized water, EtAce: ethyl acetate. * H. cordata extracts that were used in this study.