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Select item 27666721.

Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect

Michael E. Greenberg, Jonathan D. Smith, Ephraim Sehayek

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11): 1745–1750. Published online 2009 Aug 6. doi: 10.1161/ATVBAHA.109.194605

PMCID:: PMC2766672

Abstract Article PDF–751K

Select item 26060432.

CHOLESTEROL ABSORPTION FROM THE INTESTINE IS A MAJOR DETERMINANT OF REVERSE CHOLESTEROL TRANSPORT FROM PERIPHERAL TISSUE MACROPHAGES

Ephraim Sehayek, Stanley L. Hazen

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2008 Dec 22.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Jul; 28(7): 1296–1297. Published online 2008 Apr 17. doi: 10.1161/ATVBAHA.108.165803

PMCID:: PMC2606043

Abstract Article PDF–194K

Select item 36993953.

Targeting of Acyl-CoA synthetase 5 decreases jejunal fatty acid activation with no effect on dietary long-chain fatty acid absorption

Nahum Meller, Michelle E Morgan, Winifred PS Wong, Jessica B Altemus, Ephraim Sehayek

Lipids Health Dis. 2013; 12: 88. Published online 2013 Jun 14. doi: 10.1186/1476-511X-12-88

PMCID:: PMC3699395

Abstract Article PDF–464K

Select item 17509134.

Identification of quantitative trait loci affecting body composition in a mouse intercross

James A. Vitarius, Ephraim Sehayek, Jan L. Breslow

Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52): 19860–19865. Published online 2006 Dec 18. doi: 10.1073/pnas.0609232103

PMCID:: PMC1750913

Abstract Article PDF–531K

Select item 25833535.

Bioinformatics Tools Enabling U-Statistics for Microarrays

Knut M. Wittkowski, Asifa Haider, Ephraim Sehayek, Mayte Suárez-Fariñas, Maurizio Pellegrino, Alexandre Peshansky, Cameron Coffran, Sanford Coker

Conf Proc IEEE Eng Med Biol Soc. Author manuscript; available in PMC 2008 Nov 17.

Published in final edited form as: Conf Proc IEEE Eng Med Biol Soc. 2006; 1: 3464–3469. doi: 10.1109/IEMBS.2006.260846

PMCID:: PMC2583353

Abstract Article PDF–1.3M

Select item 162576.

Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: Studies in C57BL/6 apolipoprotein E knockout mice

Ephraim Sehayek, Sarah Shefer, Lien B. Nguyen, Jennie G. Ono, Martin Merkel, Jan L. Breslow

Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3433–3437. Published online 2000 Mar 21. doi: 10.1073/pnas.050016197

PMCID:: PMC16257

Abstract Article PDF–1.0M

Select item 1245087.

The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6

Raymond E. Soccio, Rachel M. Adams, Michael J. Romanowski, Ephraim Sehayek, Stephen K. Burley, Jan L. Breslow

Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 6943–6948. doi: 10.1073/pnas.052143799

PMCID:: PMC124508

Abstract Article PDF–850K

Select item 113347028.

Reply: Origins and Previous Applications of Causal-Benefit Models

Ciaran Kohli-Lynch, George Thanassoulis, Michael Pencina, Daniel Sehayek, Karol Pencina, Andrew Moran, Allan D. Sniderman

JACC Adv. 2024 Sep; 3(9): 101090. Published online 2024 Jul 29. doi: 10.1016/j.jacadv.2024.101090

PMCID:: PMC11334702

Article PDF–83K

Select item 96808039.

Rapid ensemble measurement of protein diffusion and probe blinking dynamics in cells

Simon Sehayek, Xiyu Yi, Shimon Weiss, Paul W. Wiseman

Biophys Rep (N Y) 2021 Dec 8; 1(2): 100015. Published online 2021 Sep 3. doi: 10.1016/j.bpr.2021.100015

PMCID:: PMC9680803

Abstract Article PDF–2.1M

Select item 361795510.

Cathepsin B is a novel gender-dependent determinant of cholesterol absorption from the intestine

Winifred P. S. Wong, Jessica B. Altemus, James F. Hester, Ernest R. Chan, Jean-François Côté, David Serre, Ephraim Sehayek

J Lipid Res. 2013 Mar; 54(3): 816–822. doi: 10.1194/jlr.M034579

PMCID:: PMC3617955

Abstract Article PDF–726K

Select item 272899011.

Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae

Eimear E. Kenny, Alexander Gusev, Kaitlin Riegel, Dieter Lütjohann, Jennifer K. Lowe, Jacqueline Salit, Julian B. Maller, Markus Stoffel, Mark J. Daly, David M. Altshuler, Jeffrey M. Friedman, Jan L. Breslow, Itsik Pe'er, Ephraim Sehayek

Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33): 13886–13891. Published online 2009 Aug 10. doi: 10.1073/pnas.0907336106

PMCID:: PMC2728990

Abstract Article PDF–904K

Select item 1119872112.

The Causal-Benefit Model to Prevent Cardiovascular Events

Ciaran Kohli-Lynch, George Thanassoulis, Michael Pencina, Daniel Sehayek, Karol Pencina, Andrew Moran, Allan D. Sniderman

JACC Adv. 2024 Mar; 3(3): 100825. Published online 2024 Jan 22. doi: 10.1016/j.jacadv.2023.100825

PMCID:: PMC11198721

Abstract Article PDF–1.0M

Select item 356386713.

Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1

Byron H. Lee, Margaret G. Taylor, Peggy Robinet, Jonathan D. Smith, Jessica Schweitzer, Ephraim Sehayek, Sara M. Falzarano, Cristina Magi-Galluzzi, Eric A. Klein, Angela H. Ting

Cancer Res. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Cancer Res. 2013 Feb 1; 73(3): 1211–1218. Published online 2012 Dec 11. doi: 10.1158/0008-5472.CAN-12-3128

PMCID:: PMC3563867

Abstract Article PDF–2.8M

Select item 2148414.

Biliary cholesterol excretion: A novel mechanism that regulates dietary cholesterol absorption

Ephraim Sehayek, Jennie G. Ono, Sarah Shefer, Lien B. Nguyen, Nan Wang, Ashok K. Batta, Gerald Salen, Jonathan D. Smith, Alan R. Tall, Jan L. Breslow

Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17): 10194–10199. doi: 10.1073/pnas.95.17.10194

PMCID:: PMC21484

Abstract Article PDF–208K

Select item 394088115.

Maternal Nutrition Induces Pervasive Gene Expression Changes but No Detectable DNA Methylation Differences in the Liver of Adult Offspring

Matthew V. Cannon, David A. Buchner, James Hester, Hadley Miller, Ephraim Sehayek, Joseph H. Nadeau, David Serre

PLoS One. 2014; 9(3): e90335. Published online 2014 Mar 3. doi: 10.1371/journal.pone.0090335

PMCID:: PMC3940881

Abstract Article PDF–1.0M

Select item 13859116.

Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J × CASA/Rk intercross

Ephraim Sehayek, Elizabeth M. Duncan, Dieter Lutjohann, Klaus von Bergmann, Jennie G. Ono, Ashok K. Batta, Gerald Salen, Jan L. Breslow

Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25): 16215–16219. Published online 2002 Nov 22. doi: 10.1073/pnas.212640599

PMCID:: PMC138591

Abstract Article PDF–243K

Select item 924267217.

Liquid First Is “Solid” in Naïve Non-Small Cell Lung Cancer Patients: Faster Turnaround Time With High Concordance to Solid Next-Generation Sequencing

Or Sehayek, Waleed Kian, Amir Onn, Ronen Stoff, Hadas Gantz Sorotsky, Melanie Zemel, Jair Bar, Yulia Dudnik, Hovav Nechushtan, Yakir Rottenberg, Lior Soussan-Gutman, Addie Dvir, Laila C. Roisman, Nir Peled

Front Oncol. 2022; 12: 912801. Published online 2022 Jun 15. doi: 10.3389/fonc.2022.912801

PMCID:: PMC9242672

Abstract Article PDF–682K

Select item 653181318.

Transmission of Mechanical Information by Purinergic Signaling

Nicholas Mikolajewicz, Simon Sehayek, Paul W. Wiseman, Svetlana V. Komarova

Biophys J. 2019 May 21; 116(10): 2009–2022. Published online 2019 Apr 22. doi: 10.1016/j.bpj.2019.04.012

PMCID:: PMC6531813

Abstract Article PDF–2.2M

Select item 35701519.

Cholesterol feeding of mice expressing cholesterol 7α-hydroxylase increases bile acid pool size despite decreased enzyme activity

Michaela Tiemann, Zhihua Han, Raymond Soccio, Jaya Bollineni, Sarah Shefer, Ephraim Sehayek, Jan L. Breslow

Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7): 1846–1851. Published online 2004 Feb 4. doi: 10.1073/pnas.0308426100

PMCID:: PMC357015

Abstract Article PDF–431K

Select item 44326520.

Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix.

S Eisenberg, E Sehayek, T Olivecrona, I Vlodavsky

J Clin Invest. 1992 Nov; 90(5): 2013–2021. doi: 10.1172/JCI116081

PMCID:: PMC443265

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E Sehayek (106)
PMC
H Sklenar (619)
PMC
Homo sapiens NDRG family member 4 (NDRG4), transcript variant 19, mRNA
Homo sapiens NDRG family member 4 (NDRG4), transcript variant 19, mRNA
gi|1807428588|ref|NM_001378341.1|

Nucleotide
RecName: Full=Proprotein convertase subtilisin/kexin type 4; AltName: Full=KEX2-...
RecName: Full=Proprotein convertase subtilisin/kexin type 4; AltName: Full=KEX2-like endoprotease 3; AltName: Full=Neuroendocrine convertase 3; Short=NEC 3; AltName: Full=Prohormone convertase 3; Flags: Precursor
gi|128005|sp|P29121.1|PCSK4_MOUSE

Protein

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