Chinensinaphthol - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 23

<< First< Prev

Page of 2

Next >Last >>

Select item 65229821.

A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees

Songtao Wu, Yanfang Yang, Bo Liu, Zhoutao Xie, Weichen Xiong, Pengfei Hao, Wenping Xiao, Yuan Sun, Zhongzhu Ai, Hezhen Wu

J Enzyme Inhib Med Chem. 2019; 34(1): 999–1009. Published online 2019 May 10. doi: 10.1080/14756366.2019.1609468

PMCID:: PMC6522982

Abstract Article PDF–1.5M

Select item 39681692.

Evaluation and Structure-Activity Relationship Analysis of a New Series of Arylnaphthalene lignans as Potential Anti-Tumor Agents

Jiaoyang Luo, Yichen Hu, Weijun Kong, Meihua Yang

PLoS One. 2014; 9(3): e93516. Published online 2014 Mar 27. doi: 10.1371/journal.pone.0093516

PMCID:: PMC3968169

Abstract Article PDF–1.8M

Select item 112015943.

Identification of Key Hypolipidemic Components and Exploration of the Potential Mechanism of Total Flavonoids from Rosa sterilis Based on Network Pharmacology, Molecular Docking, and Zebrafish Experiment

Boxiao Wu, Churan Li, Xulu Luo, Huan Kan, Yonghe Li, Yingjun Zhang, Xiaoping Rao, Ping Zhao, Yun Liu

Curr Issues Mol Biol. 2024 Jun; 46(6): 5131–5146. Published online 2024 May 23. doi: 10.3390/cimb46060308

PMCID:: PMC11201594

Abstract Article PDF–4.8M

Select item 77454344.

Extract from Rostellularia procumbens (L.) Nees Inhibits Thrombosis and Platelet Aggregation by Regulating Integrin β₃ and MAPK Pathways

Ying Zhang, Zongchao Hong, Zixin Yuan, Tianshun Wang, Xingpan Wu, Bo Liu, Zhongzhu Ai, Hezhen Wu, Yanfang Yang

ACS Omega. 2020 Dec 15; 5(49): 32123–32130. Published online 2020 Dec 3. doi: 10.1021/acsomega.0c05227

PMCID:: PMC7745434

Abstract Article PDF–5.7M

Select item 85733575.

Exploring Multifunctional Bioactive Components from Podophyllum sinense Using Multi-Target Ultrafiltration

Huixia Feng, Guilin Chen, Yongli Zhang, Mingquan Guo

Front Pharmacol. 2021; 12: 749189. Published online 2021 Oct 25. doi: 10.3389/fphar.2021.749189

PMCID:: PMC8573357

Abstract Article PDF–3.2M

Select item 83874326.

Reveals of candidate active ingredients in Justicia and its anti-thrombotic action of mechanism based on network pharmacology approach and experimental validation

Zongchao Hong, Ting Zhang, Ying Zhang, Zhoutao Xie, Yi Lu, Yunfeng Yao, Yanfang Yang, Hezhen Wu, Bo Liu

Sci Rep. 2021; 11: 17187. Published online 2021 Aug 25. doi: 10.1038/s41598-021-96683-z

PMCID:: PMC8387432

Abstract Article PDF–8.2M

Select item 37158057.

Antiplatelet Effect and Selective Binding to Cyclooxygenase (COX) by Molecular Docking Analysis of Flavonoids and Lignans

Chien-Ming Wu, Shu-Chun Wu, Wan-Jung Chung, Hsien-Cheng Lin, Kun-Tze Chen, Yu-Chian Chen, Mei-Feng Hsu, Jwu-Maw Yang, Jih-Pyang Wang, Chun-Nan Lin

Int J Mol Sci. 2007 Aug; 8(8): 830–841. Published online 2007 Aug 22.

PMCID:: PMC3715805

Abstract Article PDF–404K

Select item 57854558.

Screening for cytotoxic chemical constituents from Justicia procumbens by HPLC–DAD–ESI–MS and NMR

Bo Liu, Yanfang Yang, Hongbin Liu, Zhoutao Xie, Qun Li, Meng Deng, Fangping Li, Jingling Peng, Hezhen Wu

Chem Cent J. 2018; 12: 6. Published online 2018 Jan 25. doi: 10.1186/s13065-018-0371-z

PMCID:: PMC5785455

Abstract Article PDF–2.1M

Select item 65902589.

A Novel Antiplatelet Aggregation Target of Justicidin B Obtained From Rostellularia Procumbens (L.) Nees

Yan-Fang Yang, Song-Tao Wu, Bo Liu, Zhou-Tao Xie, Wei-Chen Xiong, Peng-Fei Hao, Wen-Ping Xiao, Yuan Sun, Zhong-Zhu Ai, Peng-Tao You, He-Zhen Wu

Front Pharmacol. 2019; 10: 688. Published online 2019 Jun 14. doi: 10.3389/fphar.2019.00688

PMCID:: PMC6590258

Abstract Article PDF–2.7M

Select item 992042910.

Overview of the Justicia Genus: Insights into Its Chemical Diversity and Biological Potential

Marcos Rodrigo Beltrão Carneiro, Lóide Oliveira Sallum, José Luís Rodrigues Martins, Josana de Castro Peixoto, Hamilton Barbosa Napolitano, Lucimar Pinheiro Rosseto

Molecules. 2023 Feb; 28(3): 1190. Published online 2023 Jan 25. doi: 10.3390/molecules28031190

PMCID:: PMC9920429

Abstract Article PDF–4.7M

Select item 644149211.

Potential Anticancer Agents Characterized from Selected Tropical Plants

Yulin Ren, Esperanza J. Carcache de Blanco, James R. Fuchs, Djaja D. Soejarto, Joanna E. Burdette, Steven M. Swanson, A. Douglas Kinghorn

J Nat Prod. Author manuscript; available in PMC 2020 Mar 22.

Published in final edited form as: J Nat Prod. 2019 Mar 22; 82(3): 657–679. Published online 2019 Mar 4. doi: 10.1021/acs.jnatprod.9b00018

PMCID:: PMC6441492

Abstract Article PDF–1.7M

Select item 900044112.

NMR Characterization of Lignans

Roberto Consonni, Gianluca Ottolina

Molecules. 2022 Apr; 27(7): 2340. Published online 2022 Apr 5. doi: 10.3390/molecules27072340

PMCID:: PMC9000441

Abstract Article PDF–2.4M

Select item 815745913.

Exploring the anti-HIV-1 reverse transcriptase, anti-inflammatory, anti-cancer activities and cytotoxicity of two fermented commercial herbal concoctions sold in Limpopo Province of South Africa

Matimba I. Ntlhamu, Ashwell R. Ndhlala, Peter Masoko

BMC Complement Med Ther. 2021; 21: 151. Published online 2021 May 26. doi: 10.1186/s12906-021-03321-2

PMCID:: PMC8157459

Abstract Article PDF–890K

Select item 741176314.

Comparative Metabolite Profiling of Wild and Cultivated Justicia procumbens L. Based on ¹H-NMR Spectroscopy and HPLC-DAD Analysis

Hyunyong Lee, Jihyun Jeon, Joobyoung Yoon, Seung-Hwan Kim, Hyun Sik Choi, Jong Seung Kang, Yong Sup Lee, Mase Lee, Young Ho Kim, Hwan Bong Chang

Plants (Basel) 2020 Jul; 9(7): 860. Published online 2020 Jul 7. doi: 10.3390/plants9070860

PMCID:: PMC7411763

Abstract Article PDF–3.2M

Select item 1036725515.

Mechanisms of Rostellularia procumbens (L.) Nees on treating chronic glomerulonephritis explored by network pharmacology, RNA-seq, and in vitro experiments

Mengfan Wang, Yi Zhou, Qiuyuan Jian, Zhongzhu Ai, Shanshan Zhou

BMC Complement Med Ther. 2023; 23: 263. Published online 2023 Jul 24. doi: 10.1186/s12906-023-04079-5

PMCID:: PMC10367255

Abstract Article PDF–2.3M

Select item 546581316.

Flavonoids: an overview

A. N. Panche, A. D. Diwan, S. R. Chandra

J Nutr Sci. 2016; 5: e47. Published online 2016 Dec 29. doi: 10.1017/jns.2016.41

PMCID:: PMC5465813

Abstract Article PDF–596K

Select item 407366117.

Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei

Yulin Ren, Daniel D. Lantvit, Youcai Deng, Ragu Kanagasabai, Judith C. Gallucci, Tran Ngoc Ninh, Hee-Byung Chai, Djaja D. Soejarto, James R. Fuchs, Jack C. Yalowich, Jianhua Yu, Steven M. Swanson, A. Douglas Kinghorn

J Nat Prod. 2014 Jun 27; 77(6): 1494–1504. Published online 2014 Jun 12. doi: 10.1021/np5002785

PMCID:: PMC4073661

Abstract Article PDF–2.8M

Select item 632126118.

Advances in the Synthesis of Lignan Natural Products

Xianhe Fang, Xiangdong Hu

Molecules. 2018 Dec; 23(12): 3385. Published online 2018 Dec 19. doi: 10.3390/molecules23123385

PMCID:: PMC6321261

Abstract Article PDF–5.9M

Select item 600856519.

6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca²⁺ Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells

Jiaoyang Luo, Jiaan Qin, Yanwei Fu, Shanshan Zhang, Xingguo Zhang, Meihua Yang

Front Pharmacol. 2018; 9: 601. Published online 2018 Jun 6. doi: 10.3389/fphar.2018.00601

PMCID:: PMC6008565

Abstract Article PDF–1.0M

Select item 907864220.

Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

Chuang Zhao, K. P. Rakesh, Saira Mumtaz, Balakrishna Moku, Abdullah M. Asiri, Hadi M. Marwani, H. M. Manukumar, Hua-Li Qin

RSC Adv. 2018 Feb 28; 8(17): 9487–9502. Published online 2018 Mar 6. doi: 10.1039/c7ra13754k

PMCID:: PMC9078642

Abstract Article PDF–1.8M

<< First< Prev

Page of 2

Next >Last >>

Supplemental Content

Filter your results:

All (23)
NIH grants (2)
Embargoed (0)

Manage Filters

PMC Images search for Chinensinaphthol

Figure 5.

Molecular interaction of integrin α_IIbβ₃ using NT.LabelFree analysis. (A) MST time traces of 16 different neojusticin B concentrations (ranging from 0.0173 to 71 mM). (B) MST time traces of 16 different chinensinaphthol methyl ether concentrations (ranging from 0.00845 to 69.3 mM). (C) Dependence of the MST signal on the neojusticin B concentration (measured 30 s after turning on heating; data from A). The solid line is a fit with Michaelis–Menten kinetics, yielding an apparent dissociation constant of K_d = 113.47 ± 76.536 nm. (D) Dependence of the MST signal on the chinensinaphthol methyl ether concentration (measured 30 s after turning on heating; data from B). The solid line is a fit with Michaelis–Menten kinetics, yielding an apparent dissociation constant of K_d = 25.22 ± 34.934 nm.

A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees

J Enzyme Inhib Med Chem. 2019;34(1):999-1009.
Figure 6.

Molecular interaction of integrin α_IIbβ₃ using NT.115 analysis. (A) MST time traces of 16 different neojusticin B concentrations (ranging from 0.000173 to 2.84 mM). (B) MST time traces of 16 different chinensinaphthol methyl ether concentrations (ranging from 0.000677 to 5.55 mM). (C) Dependence of the MST signal on the neojusticin B concentration (measured 30 s after turning on heating; data from A). The solid line is a fit with Michaelis–Menten kinetics, yielding an apparent dissociation constant of K_d = 1.1592 ± 2.5447 μm. (D) Dependence of the MST signal on the chinensinaphthol methyl ether concentration (measured 30 s after turning on heating; data from B). The solid line is a fit with Michaelis–Menten kinetics, yielding an apparent dissociation constant of K_d = 9.8229 ± 0.21873 μm.

A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees

J Enzyme Inhib Med Chem. 2019;34(1):999-1009.
Figure 1Chemical structures of 6′-hydroxy justicidin B (HJB), 6′-hydroxy justicidin A (HJA), justicidin B (JB), chinensinaphthol methyl ether (CME), Taiwanin E methyl ether (TEME), etoposide (ETO), paclitaxel (TAX) and podophyllotoxin (POD).

Evaluation and Structure-Activity Relationship Analysis of a New Series of Arylnaphthalene lignans as Potential Anti-Tumor Agents

PLoS One. 2014;9(3):e93516.
Figure 1

Main active ingredients in RPE. (A) HPLC of RPE(1:6′-hydroxy justicidin B, 2: JDB, 3:CME, 4: neojusticidin B, and 5: neojusticidin A). (B) Chemical structures of them. (a: 6′-Hydroxy justicidin B, b: justiscidin B, c: chinensinaphthol methyl ether, d: neojusticidin B, and e: neojusticidin A).

Extract from Rostellularia procumbens (L.) Nees Inhibits Thrombosis and Platelet Aggregation by Regulating Integrin β3 and MAPK Pathways

ACS Omega. 2020 Dec 15;5(49):32123-32130.