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Select item 79490971.

Human Gb3/CD77 synthase produces P1 glycotope-capped N-glycans, which mediate Shiga toxin 1 but not Shiga toxin 2 cell entry

Katarzyna Szymczak-Kulus, Sascha Weidler, Anna Bereznicka, Krzysztof Mikolajczyk, Radoslaw Kaczmarek, Bartosz Bednarz, Tao Zhang, Anna Urbaniak, Mariusz Olczak, Enoch Y. Park, Edyta Majorczyk, Katarzyna Kapczynska, Jolanta Lukasiewicz, Manfred Wuhrer, Carlo Unverzagt, Marcin Czerwinski

J Biol Chem. 2021 Jan-Jun; 296: 100299. Published online 2021 Jan 15. doi: 10.1016/j.jbc.2021.100299

PMCID:: PMC7949097

Abstract Article PDF–3.2M

Select item 51493932.

Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase

Radoslaw Kaczmarek, Katarzyna Mikolajewicz, Katarzyna Szymczak, Maria Duk, Edyta Majorczyk, Anna Krop-Watorek, Anna Buczkowska, Marcin Czerwinski

Glycoconj J. 2016; 33(6): 963–973. Published online 2016 Aug 18. doi: 10.1007/s10719-016-9716-9

PMCID:: PMC5149393

Abstract Article PDF–2.0M

Select item 34880913.

A Single Point Mutation in the Gene Encoding Gb3/CD77 Synthase Causes a Rare Inherited Polyagglutination Syndrome

Anna Suchanowska, Radoslaw Kaczmarek, Maria Duk, Jolanta Lukasiewicz, Dorota Smolarek, Edyta Majorczyk, Ewa Jaskiewicz, Anna Laskowska, Kazimiera Wasniowska, Magdalena Grodecka, Elwira Lisowska, Marcin Czerwinski

J Biol Chem. 2012 Nov 2; 287(45): 38220–38230. Published online 2012 Sep 10. doi: 10.1074/jbc.M112.408286

Correction in:: J Biol Chem. 2013 Jan 4; 288(1): 294.

PMCID:: PMC3488091

Abstract Article PDF–1.8M

Select item 84662134.

Two Paralogous Gb3/CD77 Synthases in Birds Show Different Preferences for Their Glycoprotein and Glycosphingolipid Substrates

Anna Bereznicka, Krzysztof Mikolajczyk, Katarzyna Szymczak-Kulus, Katarzyna Kapczynska, Edyta Majorczyk, Anna Modlinska, Tomasz Piasecki, Radoslaw Kaczmarek, Marcin Czerwinski

Int J Mol Sci. 2021 Sep; 22(18): 9761. Published online 2021 Sep 9. doi: 10.3390/ijms22189761

PMCID:: PMC8466213

Abstract Article PDF–3.8M

Select item 59274445.

Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system

Radoslaw Kaczmarek, Katarzyna Szymczak-Kulus, Anna Bereźnicka, Krzysztof Mikołajczyk, Maria Duk, Edyta Majorczyk, Anna Krop-Watorek, Elżbieta Klausa, Joanna Skowrońska, Bogumiła Michalewska, Ewa Brojer, Marcin Czerwinski

PLoS One. 2018; 13(4): e0196627. Published online 2018 Apr 30. doi: 10.1371/journal.pone.0196627

PMCID:: PMC5927444

Abstract Article PDF–7.7M

Select item 73631456.

Blood group P1 antigen–bearing glycoproteins are functional but less efficient receptors of Shiga toxin than conventional glycolipid-based receptors

Kanta Morimoto, Noriko Suzuki, Isei Tanida, Soichiro Kakuta, Yoko Furuta, Yasuo Uchiyama, Kentaro Hanada, Yusuke Suzuki, Toshiyuki Yamaji

J Biol Chem. 2020 Jul 10; 295(28): 9490–9501. Published online 2020 May 14. doi: 10.1074/jbc.RA120.013926

PMCID:: PMC7363145

Abstract Article PDF–2.7M

Select item 67091207.

The synonymous 903C>G mutation in the alpha 1,4-galactosyltransferase gene in a Chinese woman with habitual abortion: A case report

Xiaoying Lv, Yongquan Chen, Yuanyuan Luo, Lingbo Li, Houzhao Wang

Medicine (Baltimore) 2019 Aug; 98(31): e16361. Published online 2019 Aug 2. doi: 10.1097/MD.0000000000016361

Correction in:: Medicine (Baltimore). 2019 Aug; 98(33): e16971.

PMCID:: PMC6709120

Abstract Article PDF–270K

Select item 62490788.

B CELL PHENOTYPES IN BABOONS WITH PIG ARTERY PATCH GRAFTS RECEIVING CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY

Takayuki Yamamoto, Qi Li, Hidetaka Hara, Liaoran Wang, Hongmin Zhou, Juan Li, Devin E. Eckhoff, A. Joseph Tector, Edwin C. Klein, Ray Lovingood, Mohamed Ezzelarab, David Ayares, Yi Wang, David K.C. Cooper, Hayato Iwase

Transpl Immunol. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Transpl Immunol. 2018 Dec; 51: 12–20. Published online 2018 Aug 6. doi: 10.1016/j.trim.2018.08.005

PMCID:: PMC6249078

Abstract Article PDF–1.7M

Select item 56732339.

An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major

Eva Iniguez, Nathaniel S. Schocker, Krishanthi Subramaniam, Susana Portillo, Alba L. Montoya, Waleed S. Al-Salem, Caresse L. Torres, Felipe Rodriguez, Otacilio C. Moreira, Alvaro Acosta-Serrano, Katja Michael, Igor C. Almeida, Rosa A. Maldonado

PLoS Negl Trop Dis. 2017 Oct; 11(10): e0006039. Published online 2017 Oct 25. doi: 10.1371/journal.pntd.0006039

PMCID:: PMC5673233

Abstract Article PDF–3.8M

Select item 361794410.

Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells

Ivan U. Kouzel, Gottfried Pohlentz, Wiebke Storck, Lena Radamm, Petra Hoffmann, Martina Bielaszewska, Andreas Bauwens, Christoph Cichon, M. Alexander Schmidt, Michael Mormann, Helge Karch, Johannes Müthing

J Lipid Res. 2013 Mar; 54(3): 692–710. doi: 10.1194/jlr.M031781

PMCID:: PMC3617944

Abstract Article PDF–1.4M

Select item 297636411.

Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide

Steven D. Zumbrun, Leanne Hanson, James F. Sinclair, James Freedy, Angela R. Melton-Celsa, Jaime Rodriguez-Canales, Jeffrey C. Hanson, Alison D. O'Brien

Infect Immun. 2010 Nov; 78(11): 4488–4499. Published online 2010 Aug 23. doi: 10.1128/IAI.00620-10

PMCID:: PMC2976364

Abstract Article PDF–3.0M

Select item 289744212.

Verotoxin 2 Enhances Adherence of Enterohemorrhagic Escherichia coli O157:H7 to Intestinal Epithelial Cells and Expression of β1-Integrin by IPEC-J2 Cells

Bianfang Liu, Xianhua Yin, Yanni Feng, James R. Chambers, Aiguang Guo, Joshua Gong, Jing Zhu, Carlton L. Gyles

Appl Environ Microbiol. 2010 Jul; 76(13): 4461–4468. Published online 2010 May 7. doi: 10.1128/AEM.00182-10

PMCID:: PMC2897442

Abstract Article PDF–1.2M

Select item 676980413.

Deletion of Gb3 Synthase in Mice Resulted in the Attenuation of Bone Formation via Decrease in Osteoblasts

Kazunori Hamamura, Kosuke Hamajima, Shoyoku Yo, Yoshitaka Mishima, Koichi Furukawa, Makoto Uchikawa, Yuji Kondo, Hironori Mori, Hisataka Kondo, Kenjiro Tanaka, Ken Miyazawa, Shigemi Goto, Akifumi Togari

Int J Mol Sci. 2019 Sep; 20(18): 4619. Published online 2019 Sep 18. doi: 10.3390/ijms20184619

PMCID:: PMC6769804

Abstract Article PDF–3.1M

Select item 666034014.

First Case in Korea of a Patient With Anti-PP1Pk Antibodies: Successful Blood Management via Acute Normovolemic Hemodilution

Changhee Ha, Sooin Choi, HongBi Yu, Sejong Chun, Kyeong-Hee Kim, Jong-Hwan Lee, In Woong Han, Duck Cho

Ann Lab Med. 2019 Nov; 39(6): 602–605. Published online 2019 Jun 25. doi: 10.3343/alm.2019.39.6.602

PMCID:: PMC6660340

Article PDF–339K

Select item 640298615.

A Whole Genome Approach for Discovering the Genetic Basis of Blood Group Antigens: Independent Confirmation for P1 and Xg^a

William J. Lane, Maria Aguad, Robin Smeland-Wagman, Sunitha Vege, Helen H. Mah, Abigail Joseph, Carrie L. Blout, Tiffany T. Nguyen, Matthew S. Lebo, Manpreet Sidhu, Christine Lomas-Francis, Richard M. Kaufman, Robert C. Green, Connie M. Westhoff, MedSeq Project

Transfusion. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Transfusion. 2019 Mar; 59(3): 908–915. Published online 2018 Dec 28. doi: 10.1111/trf.15089

PMCID:: PMC6402986

Abstract Article PDF–2.0M

Select item 471548816.

A conserved structural motif mediates retrograde trafficking of Shiga toxin types 1 and 2

Andrey S. Selyunin, Somshuvra Mukhopadhyay

Traffic. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Traffic. 2015 Dec; 16(12): 1270–1287. Published online 2015 Nov 2. doi: 10.1111/tra.12338

PMCID:: PMC4715488

Abstract Article PDF–1.8M

Select item 416005317.

A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis

Atsumi Taguchi, Hiroki Maruyama, Masaaki Nameta, Tadashi Yamamoto, Junichiro Matsuda, Ashok B. Kulkarni, Hidekatsu Yoshioka, Satoshi Ishii

Biochem J. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: Biochem J. 2013 Dec 15; 456(3): 373–383. doi: 10.1042/BJ20130825

PMCID:: PMC4160053

Abstract Article PDF–4.6M

Select item 387089018.

HUMAN T CELLS UPREGULATE CD69 AFTER COCULTURE WITH XENOGENEIC GENETICALLY-MODIFIED PIG MESENCHYMAL STROMAL CELLS

Jiang Li, Oleg Andreyev, Man Chen, Michael Marco, Hayato Iwase, Cassandra Long, David Ayares, Zhongyang Shen, David K.C. Cooper, Mohamed B. Ezzelarab

Cell Immunol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Cell Immunol. 2013 Sep-Oct; 285(0): 10.1016/j.cellimm.2013.08.004. Published online 2013 Aug 29. doi: 10.1016/j.cellimm.2013.08.004

PMCID:: PMC3870890

Abstract Article PDF–3.4M

Select item 306943919.

Lipooligosaccharide of Campylobacter jejuni: SIMILARITY WITH MULTIPLE TYPES OF MAMMALIAN GLYCANS BEYOND GANGLIOSIDES

R. Scott Houliston, Evgeny Vinogradov, Monika Dzieciatkowska, Jianjun Li, Frank St. Michael, Marie-France Karwaski, Denis Brochu, Harold C. Jarrell, Craig T. Parker, Nobuhiro Yuki, Robert E. Mandrell, Michel Gilbert

J Biol Chem. 2011 Apr 8; 286(14): 12361–12370. Published online 2011 Jan 21. doi: 10.1074/jbc.M110.181750

PMCID:: PMC3069439

Abstract Article PDF–3.0M

Select item 303130820.

Increased globotriaosylceramide levels in a transgenic mouse expressing human α1,4-galactosyltransferase and a mouse model for treating Fabry disease

Chikara Shiozuka, Atsumi Taguchi, Junichiro Matsuda, Yoko Noguchi, Takanori Kunieda, Kozue Uchio-Yamada, Hidekatsu Yoshioka, Ryoji Hamanaka, Shinji Yano, Shigeo Yokoyama, Kazuaki Mannen, Ashok B. Kulkarni, Koichi Furukawa, Satoshi Ishii

J Biochem. 2011 Feb; 149(2): 161–170. Published online 2010 Oct 19. doi: 10.1093/jb/mvq125