A multiple sequence alignment of AsKC11 and homologous Kunitz-type peptides. AsKC11: snakelocks anemone Anemonia sulcata, a synonym of Anemonia viridis, Uniprot accession number: P0DN15. HCRG1: leathery sea anemone Heteractis crispa, Uniprot accession number: C0HJU6. ShPI-I: sun anemone Stichodactyla helianthus, Uniprot accession number: P31713. APHC1: leathery sea anemone Heteractis crispa, Uniprot accession number: B2G331. APHC3: leathery sea anemone Heteractis crispa, Uniprot accession number: C0HJF3. HCRG21: leathery sea anemone Heteractis crispa, Uniprot accession number: P0DL86. APHC2: leathery sea anemone Heteractis crispa, Uniprot accession number: C0HJF4. InhVJ: leathery sea anemone Heteractis crispa, Uniprot accession number: P0DMJ5. APEKTx1: green aggregating anemone Anthopleura elegantissima, Uniprot accession number: P86862. BPTI: bovine Bos taurus, Uniprot accession number: P00974. Delta-DTX: eastern green mamba Dendroaspis angusticeps, Uniprot accession number: P00982. DTX-K: black mamba Dendroaspis polylepis, Uniprot accession number: P00981. Alpha-DTX: eastern green mamba Dendroaspis angusticeps, Uniprot accession number: P00980. DTX-I: black mamba Dendroaspis polylepis, Uniprot accession number: P00979. Cysteine residues are indicated in red, key residues for KV channel inhibition are boxed in yellow, key residues for trypsin inhibition are boxed in green.