U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination
You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 46

1.
Novel 3-Nitro-1H-1,2,4-triazole-based Aliphatic and Aromatic Amines as anti-Chagasic Agents
Maria V. Papadopoulou, Bernadette Bourdin Trunz, William D. Bloomer, Caroline McKenzie, Shane R. Wilkinson, Chaiya Prasittichai, Reto Brun, Marcel Kaiser, Els Torreele
J Med Chem. Author manuscript; available in PMC 2012 Dec 8.
Published in final edited form as: J Med Chem. 2011 Dec 8; 54(23): 8214–8223. Published online 2011 Nov 4. doi: 10.1021/jm201215n
PMCID:
PMC3258117
AbstractArticlePDF–586K
2.
Palladium-Catalysed Synthesis and Transformation of Quinolones
Vera L. M. Silva, Artur M. S. Silva
Molecules. 2019 Jan; 24(2): 228. Published online 2019 Jan 9. doi: 10.3390/molecules24020228
PMCID:
PMC6359680
AbstractArticlePDF–24M
3.
Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing Escherichia coli and MRSA, Docking Studies, and Structural Features Determination through Computational Approach
Mahwish Arshad, Nasir Rasool, Muhammad Usman Qamar, Syed Adnan Ali Shah, Zainul Amiruddin Zakaria
Molecules. 2022 Jun; 27(12): 3732. Published online 2022 Jun 10. doi: 10.3390/molecules27123732
PMCID:
PMC9230019
AbstractArticlePDF–3.7M
4.
Anti-Mycobacterial N-(2-Arylethyl)quinolin-3-amines Inspired by Marine Sponge-Derived Alkaloid
Junya Mukomura, Hiroki Nonaka, Hiromasa Sato, Maho Kishimoto, Masayoshi Arai, Naoyuki Kotoku
Molecules. 2022 Dec; 27(24): 8701. Published online 2022 Dec 8. doi: 10.3390/molecules27248701
PMCID:
PMC9781020
AbstractArticlePDF–1.0M
5.
Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors
Tiantian Fan, Yinchun Ji, Danqi Chen, Xia Peng, Jing Ai, Bing Xiong
J Enzyme Inhib Med Chem. 2023; 38(1): 282–293. Published online 2022 Nov 21. doi: 10.1080/14756366.2022.2148317
PMCID:
PMC9683047
AbstractArticlePDF–2.2M
6.
Improvement of Aqueous Solubility of Lapatinib-derived Analogs: Identification of a Quinolinimine as a Lead for Human African Trypanosomiasis Drug Development
Kelly A. Bachovchin, Amrita Sharma, Seema Bag, Dana M. Klug, Katherine M. Schneider, Baljinder Singh, Hitesh B. Jalani, Melissa J. Buskes, Naimee Mehta, Scott Tanghe, Jeremiah D. Momper, Richard J. Sciotti, Ana Rodriguez, Kojo Mensa-Wilmot, Michael P. Pollastri, Lori Ferrins
J Med Chem. Author manuscript; available in PMC 2020 Jan 24.
Published in final edited form as: J Med Chem. 2019 Jan 24; 62(2): 665–687. Published online 2019 Jan 10. doi: 10.1021/acs.jmedchem.8b01365
PMCID:
PMC6556231
AbstractArticlePDF–999K
7.
Recent Advances in the Synthesis and Biological Activity of 8-Hydroxyquinolines
Haythem A. Saadeh, Kamal A. Sweidan, Mohammad S. Mubarak
Molecules. 2020 Sep; 25(18): 4321. Published online 2020 Sep 21. doi: 10.3390/molecules25184321
Correction in:
Molecules. 2022 Jul; 27(13): 4306.
PMCID:
PMC7571046
AbstractArticlePDF–5.9M
8.
Optimization of 4-Anilinoquinolines as Dengue Virus Inhibitors
Pei-Tzu Huang, Sirle Saul, Shirit Einav, Christopher R. M. Asquith
Molecules. 2021 Dec; 26(23): 7338. Published online 2021 Dec 3. doi: 10.3390/molecules26237338
PMCID:
PMC8659069
AbstractArticlePDF–6.6M
9.
Nitrile In The Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors
Maris A. Cinelli, Huiying Li, Georges Chreifi, Thomas L. Poulos, Richard B. Silverman
J Med Chem. Author manuscript; available in PMC 2018 May 11.
Published in final edited form as: J Med Chem. 2017 May 11; 60(9): 3958–3978. Published online 2017 Apr 19. doi: 10.1021/acs.jmedchem.7b00259
Correction in:
J Med Chem. 2019 Jan 24; 62(2): 1075.
PMCID:
PMC5567828
AbstractArticlePDF–3.2M
10.
Synthesis and evaluation of 7-substituted 4-aminoquinoline analogs for antimalarial activity
Jong Yeon Hwang, Takashi Kawasuji, David J. Lowes, Julie A. Clark, Michele C. Connelly, Fangyi Zhu, W. Armand Guiguemde, Martina S. Sigal, Emily B. Wilson, Joseph L. DeRisi, R. Kiplin Guy
J Med Chem. Author manuscript; available in PMC 2013 Jul 1.
Published in final edited form as: J Med Chem. 2011 Oct 27; 54(20): 7084–7093. Published online 2011 Sep 26. doi: 10.1021/jm200636z
PMCID:
PMC3697074
AbstractArticlePDF–732K
11.
Design, Synthesis, and Structure–Activity Relationships of Highly Potent 5-HT3 Receptor Ligands
Mark H. P. Verheij, Andrew J. Thompson, Jacqueline E. van Muijlwijk-Koezen, Sarah C. R. Lummis, Rob Leurs, Iwan J. P. de Esch
J Med Chem. 2012 Oct 25; 55(20): 8603–8614. Published online 2012 Sep 24. doi: 10.1021/jm300801u
PMCID:
PMC3504484
AbstractArticlePDF–2.4M
12.
Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer
Yuting Kuang, Na Ye, Armita Kyani, Mats Ljungman, Michelle Paulsen, Haijun Chen, Mingxiang Zhou, Christopher Wild, Haiying Chen, Jia Zhou, Nouri Neamati
J Med Chem. Author manuscript; available in PMC 2022 Jun 14.
Published in final edited form as: J Med Chem. 2022 Apr 28; 65(8): 6133–6156. Published online 2022 Apr 19. doi: 10.1021/acs.jmedchem.1c02207
PMCID:
PMC9195374
AbstractArticlePDF–4.4M
13.
Novel 4-Acrylamido-Quinoline Derivatives as Potent PI3K/mTOR Dual Inhibitors: The Design, Synthesis, and in vitro and in vivo Biological Evaluation
Xiaodong Ma, Li Shen, Jiankang Zhang, Guoqiang Liu, Shuyu Zhan, Baoyue Ding, Xiaoqing Lv
Front Chem. 2019; 7: 236. Published online 2019 Apr 24. doi: 10.3389/fchem.2019.00236
PMCID:
PMC6491818
AbstractArticlePDF–3.6M
14.
Triazole-Based Inhibitors of the Wnt/β-Catenin Signaling Pathway Improve Glucose and Lipid Metabolism in Diet-Induced Obese Mice
Obinna N. Obianom, Yong Ai, Yingjun Li, Wei Yang, Dong Guo, Hong Yang, Srilatha Sakamuru, Menghang Xia, Fengtian Xue, Yan Shu
J Med Chem. Author manuscript; available in PMC 2020 Apr 28.
Published in final edited form as: J Med Chem. 2019 Jan 24; 62(2): 727–741. Published online 2019 Jan 10. doi: 10.1021/acs.jmedchem.8b01408
PMCID:
PMC7187680
AbstractArticlePDF–1.8M
15.
Determinants of Activity at Human Toll-like Receptors 7 and 8: Quantitative Structure–Activity Relationship (QSAR) of Diverse Heterocyclic Scaffolds
Euna Yoo, Deepak B. Salunke, Diptesh Sil, Xiaoqiang Guo, Alex C. D. Salyer, Alec R. Hermanson, Manoj Kumar, Subbalakshmi S. Malladi, Rajalakshmi Balakrishna, Ward H. Thompson, Hiromi Tanji, Umeharu Ohto, Toshiyuki Shimizu, Sunil A. David
J Med Chem. 2014 Oct 9; 57(19): 7955–7970. Published online 2014 Sep 5. doi: 10.1021/jm500744f
PMCID:
PMC4191598
AbstractArticlePDF–6.5M
16.
Light Activated Serotonin for Exploring Its Action in Biological Systems
Adam C. Rea, Laura N. Vandenberg, Rebecca E. Ball, Ashley A. Snouffer, Alicia G. Hudson, Yue Zhu, Duncan E. McLain, Lindsey L. Johnston, James D. Lauderdale, Michael Levin, Timothy M. Dore
Chem Biol. Author manuscript; available in PMC 2014 Dec 19.
Published in final edited form as: Chem Biol. 2013 Dec 19; 20(12): 1536–1546. Published online 2013 Dec 12. doi: 10.1016/j.chembiol.2013.11.005
PMCID:
PMC3909739
AbstractArticlePDF–1.6M
17.
Discovery of Inhibitory Fragments That Selectively Target Spire2–FMN2 Interaction
Radoslaw Kitel, Ewa Surmiak, Jan Borggräfe, Justyna Kalinowska-Tluscik, Przemyslaw Golik, Miroslawa Czub, Wiktor Uzar, Bogdan Musielak, Mariusz Madej, Grzegorz M. Popowicz, Grzegorz Dubin, Tad A. Holak
J Med Chem. 2023 Dec 14; 66(23): 15715–15727. Published online 2023 Dec 1. doi: 10.1021/acs.jmedchem.3c00877
PMCID:
PMC10726347
AbstractArticlePDF–4.4M
18.
Discovery and Optimization of Quinoline Analogues as Novel Potent Antivirals against Enterovirus D68
Xiaoyuan Li, Yuexiang Li, Shiyong Fan, Ruiyuan Cao, Xiaojia Li, Xiaomeng He, Wei Li, Longfa Xu, Tong Cheng, Honglin Li, Wu Zhong
J Med Chem. 2022 Nov 10; 65(21): 14792–14808. Published online 2022 Oct 18. doi: 10.1021/acs.jmedchem.2c01311
PMCID:
PMC9661475
AbstractArticlePDF–7.4M
19.
Optimization of Physicochemical Properties for 4-Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation
Naimee Mehta, Lori Ferrins, Susan E. Leed, Richard J. Sciotti, Michael P. Pollastri
ACS Infect Dis. Author manuscript; available in PMC 2019 Jun 20.
Published in final edited form as: ACS Infect Dis. 2018 Apr 13; 4(4): 577–591. Published online 2018 Jan 17. doi: 10.1021/acsinfecdis.7b00212
PMCID:
PMC6585443
AbstractArticlePDF–843K
20.
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)
Christopher R. M. Asquith, James M. Bennett, Lianyong Su, Tuomo Laitinen, Jonathan M. Elkins, Julie E. Pickett, Carrow I. Wells, Zengbiao Li, Timothy M. Willson, William J. Zuercher
Molecules. 2019 Nov; 24(22): 4016. Published online 2019 Nov 6. doi: 10.3390/molecules24224016
PMCID:
PMC6891286
AbstractArticlePDF–9.7M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Search details

See more...

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center