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Select item 99806551.

Discovery of orally bioavailable and brain penetrable prodrugs of the potent nSMase2 inhibitor DPTIP

Arindom Pal, Sadakatali Gori, Seung-wan Yoo, Ajit G. Thomas, Ying Wu, Jacob Friedman, Lukáš Tenora, Harshit Bhasin, Jesse Alt, Norman Haughey, Barbara S. Slusher, Rana Rais

J Med Chem. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: J Med Chem. 2022 Aug 25; 65(16): 11111–11125. Published online 2022 Aug 5. doi: 10.1021/acs.jmedchem.2c00562

PMCID:: PMC9980655

Abstract Article PDF–1.2M

Select item 31545972.

Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities

Paul Ha-Yeon Cheong, Claude Y. Legault, Joann M. Um, Nihan Çelebi-Ölçüm, K. N. Houk

Chem Rev. Author manuscript; available in PMC 2012 Aug 10.

Published in final edited form as: Chem Rev. 2011 Aug 10; 111(8): 5042–5137. Published online 2011 Jun 28. doi: 10.1021/cr100212h

PMCID:: PMC3154597

Article PDF–39M

Select item 38927693.

Potent Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors: Classical and Nonclassical 2-Amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine Antifolates

Aleem Gangjee, Yibin Qiu, Wei Li, Roy L. Kisliuk

J Med Chem. Author manuscript; available in PMC 2014 Jan 15.

Published in final edited form as: J Med Chem. 2008 Sep 25; 51(18): 5789–5797. doi: 10.1021/jm8006933

PMCID:: PMC3892769

Abstract Article PDF–927K

Select item 89232134.

Dissection and Reconstitution Provide Insights into Electron Transport in the Membrane-Bound Aldehyde Dehydrogenase Complex of Gluconacetobacter diazotrophicus

Roni Miah, Shun Nina, Takeru Murate, Naoya Kataoka, Minenosuke Matsutani, Yoshitaka Ano, Kazunobu Matsushita, Toshiharu Yakushi

J Bacteriol. 2022 Mar; 204(3): e00558-21. Prepublished online 2022 Jan 24. Published online 2022 Mar 15. doi: 10.1128/jb.00558-21

PMCID:: PMC8923213

Abstract Article PDF–1.1M

Select item 47334965.

MCR synthesis of a tetracyclic tetrazole scaffold

Pravin Patil, Kareem Khoury, Eberhardt Herdtweck, Alexander Dömling

Bioorg Med Chem. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Bioorg Med Chem. 2015 Jun 1; 23(11): 2699–2715. Published online 2014 Dec 20. doi: 10.1016/j.bmc.2014.12.021

PMCID:: PMC4733496

Abstract Article PDF–3.2M

Select item 38852476.

N9-Substituted 2,4-Diaminoquinazolines: Synthesis and Biological Evaluation of Lipophilic Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Aleem Gangjee, Ona O. Adair, Michelle Pagley, Sherry F. Queener

J Med Chem. Author manuscript; available in PMC 2014 Jan 8.

Published in final edited form as: J Med Chem. 2008 Oct 9; 51(19): 10.1021/jm800694g. Published online 2008 Sep 5. doi: 10.1021/jm800694g

Correction in:: volume 52 on page 4979

PMCID:: PMC3885247

Abstract Article PDF–884K

Select item 92729267.

Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics – synthesis and properties

Joanna Stefaniak, Michał G. Nowak, Marek Wojciechowski, Sławomir Milewski, Andrzej S. Skwarecki

J Enzyme Inhib Med Chem. 2022; 37(1): 1928–1956. Published online 2022 Jul 8. doi: 10.1080/14756366.2022.2096018

PMCID:: PMC9272926

Abstract Article PDF–4.7M

Select item 62592438.

Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst

Huwaida M. E. Hassaneen

Molecules. 2011 Jan; 16(1): 609–623. Published online 2011 Jan 17. doi: 10.3390/molecules16010609

PMCID:: PMC6259243

Abstract Article PDF–158K

Select item 58963139.

Spin-Center Shift-Enabled Direct Enantioselective α-Benzylation of Aldehydes with Alcohols

Eric D. Nacsa, David W. C. MacMillan

J Am Chem Soc. Author manuscript; available in PMC 2018 Apr 12.

Published in final edited form as: J Am Chem Soc. 2018 Mar 7; 140(9): 3322–3330. Published online 2018 Feb 22. doi: 10.1021/jacs.7b12768

PMCID:: PMC5896313

Abstract Article PDF–921K

Select item 1070593410.

The Fundamental Role of Oxime and Oxime Ether Moieties in Improving the Physicochemical and Anticancer Properties of Structurally Diverse Scaffolds

Jean Fotie, Caitlyn M. Matherne, Jasmine B. Mather, Jordan E. Wroblewski, Khaitlynn Johnson, Lara G. Boudreaux, Alba A. Perez

Int J Mol Sci. 2023 Dec; 24(23): 16854. Published online 2023 Nov 28. doi: 10.3390/ijms242316854

PMCID:: PMC10705934

Abstract Article PDF–4.4M

Select item 1100984211.

Recent advances in the transformation reactions of the Betti base derivatives

Abolfazl Olyaei, Mahdieh Sadeghpour

RSC Adv. 2024 Apr 10; 14(17): 11811–11848. Published online 2024 Apr 12. doi: 10.1039/d4ra01256a

PMCID:: PMC11009842

Abstract Article PDF–9.5M

Select item 982217312.

Recent Progress in Electrochemical Upgrading of Bio-Oil Model Compounds and Bio-Oils to Renewable Fuels and Platform Chemicals

Jeffrey R. Page, Zachary Manfredi, Stoyan Bliznakov, Julia A. Valla

Materials (Basel) 2023 Jan; 16(1): 394. Published online 2023 Jan 1. doi: 10.3390/ma16010394

PMCID:: PMC9822173

Abstract Article PDF–6.8M

Select item 681354513.

Reactivity and Synthetic Applications of Multicomponent Petasis Reactions

Peng Wu, Michael Givskov, Thomas E. Nielsen

Chem Rev. 2019 Oct 23; 119(20): 11245–11290. Published online 2019 Aug 27. doi: 10.1021/acs.chemrev.9b00214

PMCID:: PMC6813545

Abstract Article PDF–14M

Select item 705501114.

Identification of Potent Pyrazole Based APELIN Receptor (APJ) Agonists

Sanju Narayanan, Vineetha Vasukuttan, Sudarshan Rajagopal, Rangan Maitra, Scott P. Runyon

Bioorg Med Chem. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Bioorg Med Chem. 2020 Feb 15; 28(4): 115237. Published online 2019 Nov 30. doi: 10.1016/j.bmc.2019.115237

PMCID:: PMC7055011

Abstract Article PDF–1.5M

Select item 702454415.

The Pictet-Spengler Reaction Updates Its Habits

Andrea Calcaterra, Laura Mangiardi, Giuliano Delle Monache, Deborah Quaglio, Silvia Balducci, Simone Berardozzi, Antonia Iazzetti, Roberta Franzini, Bruno Botta, Francesca Ghirga

Molecules. 2020 Jan; 25(2): 414. Published online 2020 Jan 19. doi: 10.3390/molecules25020414