3,4'-Bipyridin-2'-amine - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 37

<< First< Prev

Page of 2

Next >Last >>

Select item 95064141.

Novel 2,6,9-Trisubstituted Purines as Potent CDK Inhibitors Alleviating Trastuzumab-Resistance of HER2-Positive Breast Cancers

Ratnakar Reddy Kuchukulla, Injeoung Hwang, Sang Won Park, Sojeong Moon, Suhn Hyung Kim, Sumin Kim, Hwan Won Chung, Mi-Jung Ji, Hyun-Mee Park, Gu Kong, Wooyoung Hur

Pharmaceuticals (Basel) 2022 Sep; 15(9): 1041. Published online 2022 Aug 23. doi: 10.3390/ph15091041

PMCID:: PMC9506414

Abstract Article PDF–15M

Select item 41584772.

4-{Phenyl[4-(6-phenyl-2,2′-bipyridin-4-yl)phenyl]amino}benzaldehyde

Yu-yang Zhang, Jian-Ting Pan, Jian-Yan Huang

Acta Crystallogr Sect E Struct Rep Online. 2014 Aug 1; 70(Pt 8): o840. Published online 2014 Jul 2. doi: 10.1107/S1600536814013361

PMCID:: PMC4158477

Abstract Article PDF–196K

Select item 102144563.

Molecular Catalysis of Energy Relevance in Metal–Organic Frameworks: From Higher Coordination Sphere to System Effects

Nina F. Suremann, Brian D. McCarthy, Wanja Gschwind, Amol Kumar, Ben A. Johnson, Leif Hammarström, Sascha Ott

Chem Rev. 2023 May 24; 123(10): 6545–6611. Published online 2023 May 15. doi: 10.1021/acs.chemrev.2c00587

PMCID:: PMC10214456

Abstract Article PDF–31M

Select item 59474984.

Crystal structures of a manganese(I) and a rhenium(I) complex of a bipyridine ligand with a non-coordinating benzoic acid moiety

Sheri Lense, Ilia A. Guzei, Jessica Andersen, Kong Choua Thao

Acta Crystallogr E Crystallogr Commun. 2018 May 1; 74(Pt 5): 731–736. Published online 2018 Apr 27. doi: 10.1107/S2056989018006047

PMCID:: PMC5947498

Abstract Article PDF–932K

Select item 113782985.

Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation

Izabella Góral, Tomasz Wichur, Emilia Sługocka, Przemysław Grygier, Monika Głuch-Lutwin, Barbara Mordyl, Ewelina Honkisz-Orzechowska, Natalia Szałaj, Justyna Godyń, Dawid Panek, Paula Zaręba, Anna Sarka, Paweł Żmudzki, Gniewomir Latacz, Katarzyna Pustelny, Adam Bucki, Anna Czarna, Filipe Menezes, Anna Więckowska

ACS Chem Neurosci. 2024 Sep 4; 15(17): 3181–3201. Published online 2024 Aug 19. doi: 10.1021/acschemneuro.4c00365

PMCID:: PMC11378298

Abstract Article PDF–7.6M

Select item 110895036.

Exploring Subsite Selectivity within Plasmodium vivaxN-Myristoyltransferase Using Pyrazole-Derived Inhibitors

Diego Rodríguez-Hernández, Michael K. Fenwick, Rachael Zigweid, Banumathi Sankaran, Peter J. Myler, Per Sunnerhagen, Alexis Kaushansky, Bart L. Staker, Morten Grøtli

J Med Chem. 2024 May 9; 67(9): 7312–7329. Published online 2024 Apr 29. doi: 10.1021/acs.jmedchem.4c00168

PMCID:: PMC11089503

Abstract Article PDF–10M

Select item 112733607.

Noncanonical Amino Acids in Biocatalysis

Zachary Birch-Price, Florence J. Hardy, Thomas M. Lister, Anna R. Kohn, Anthony P. Green

Chem Rev. 2024 Jul 24; 124(14): 8740–8786. Published online 2024 Jul 3. doi: 10.1021/acs.chemrev.4c00120

PMCID:: PMC11273360

Abstract Article PDF–13M

Select item 45851758.

Artificial Molecular Machines

Sundus Erbas-Cakmak, David A. Leigh, Charlie T. McTernan, Alina L. Nussbaumer

Chem Rev. 2015 Sep 23; 115(18): 10081–10206. Published online 2015 Sep 8. doi: 10.1021/acs.chemrev.5b00146

PMCID:: PMC4585175

Article PDF–62M

Select item 98416029.

Heterogeneous Electrochemical Ammonia Oxidation with a Ru-bda Oligomer Anchored on Graphitic Electrodes via CH−π Interactions

Anna M. Beiler, Alisa Denisiuk, Jan Holub, Francisco-Javier Sánchez-Baygual, Marcos Gil-Sepulcre, Mehmed Z. Ertem, Dooshaye Moonshiram, Alberto Piccioni, Antoni Llobet

ACS Energy Lett. 2023 Jan 13; 8(1): 172–178. Published online 2022 Nov 22. doi: 10.1021/acsenergylett.2c02483

PMCID:: PMC9841602

Abstract Article PDF–2.8M

Select item 346975710.

2-(3-Fluoro-4-methylsulfonylaminophenyl) Propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure Activity Relationships of 2-Amino Derivatives in the N-(6-trifluoromethyl-pyridin-3-ylmethyl) C-region

Myeong Seop Kim, HyungChul Ryu, Dong Wook Kang, Seong-Hee Cho, Sejin Seo, Young Soo Park, Mi-Yeon Kim, Eun Joo Kwak, Yong Soo Kim, Rahul S. Bhondwe, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Ian DeAndrea-Lazarus, Larry V. Pearce, Peter M. Blumberg, Robert Frank, Gregor Bahrenberg, Hannelore Stockhausen, Babette Y. Kögel, Klaus Schiene, Thomas Christoph, Jeewoo Lee

J Med Chem. Author manuscript; available in PMC 2013 Oct 11.

Published in final edited form as: J Med Chem. 2012 Oct 11; 55(19): 8392–8408. Published online 2012 Sep 20. doi: 10.1021/jm300780p

PMCID:: PMC3469757

Abstract Article PDF–3.0M

Select item 656131111.

Electronic Effects of Substituents on fac-M(bpy-R)(CO)₃ (M = Mn, Re) Complexes for Homogeneous CO₂ Electroreduction

Laura Rotundo, Emanuele Azzi, Annamaria Deagostino, Claudio Garino, Luca Nencini, Emanuele Priola, Pierluigi Quagliotto, Riccardo Rocca, Roberto Gobetto, Carlo Nervi

Front Chem. 2019; 7: 417. Published online 2019 Jun 5. doi: 10.3389/fchem.2019.00417

PMCID:: PMC6561311

Abstract Article PDF–2.1M

Select item 728513512.

Photoactivatable Surface-Functionalized Diatom Microalgae for Colorectal Cancer Targeted Delivery and Enhanced Cytotoxicity of Anticancer Complexes

Joachim Delasoie, Philippe Schiel, Sandra Vojnovic, Jasmina Nikodinovic-Runic, Fabio Zobi

Pharmaceutics. 2020 May; 12(5): 480. Published online 2020 May 25. doi: 10.3390/pharmaceutics12050480

PMCID:: PMC7285135

Abstract Article PDF–3.2M

Select item 1006165613.

Green Synthesis of Novel Pyridines via One-Pot Multicomponent Reaction and Their Anti-Inflammatory Evaluation

Hany M. Abd El-Lateef, Antar A. Abdelhamid, Mai M. Khalaf, Mohamed Gouda, Nadia. A. A. Elkanzi, Hemdan El-Shamy, Ali M. Ali

ACS Omega. 2023 Mar 28; 8(12): 11326–11334. Published online 2023 Mar 16. doi: 10.1021/acsomega.3c00066

PMCID:: PMC10061656

Abstract Article PDF–1.9M

Select item 858199914.

Reticular-Chemistry-Inspired Supramolecule Design as a Tool to Achieve Efficient Photocatalysts for CO₂ Reduction

Bilal Masood Pirzada, Arif Hassan Dar, M. Nasiruzzaman Shaikh, Ahsanulhaq Qurashi

ACS Omega. 2021 Nov 9; 6(44): 29291–29324. Published online 2021 Oct 26. doi: 10.1021/acsomega.1c04018

PMCID:: PMC8581999

Abstract Article PDF–6.1M

Select item 650478515.

An Ir(III) Complex Photosensitizer With Strong Visible Light Absorption for Photocatalytic CO₂ Reduction

Yusuke Kuramochi, Osamu Ishitani

Front Chem. 2019; 7: 259. Published online 2019 May 1. doi: 10.3389/fchem.2019.00259

PMCID:: PMC6504785

Abstract Article PDF–3.1M

Select item 1038829216.

Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6

Takaya Togo, Linh Tram, Laura G. Denton, Xochina ElHilali-Pollard, Jun Gu, Jinglei Jiang, Chenglei Liu, Yan Zhao, Yanlong Zhao, Yinzhe Zheng, Yunping Zheng, Jingjing Yang, Panpan Fan, Michelle R. Arkin, Harri Härmä, Deqian Sun, Stacie S. Canan, Steven E. Wheeler, Adam R. Renslo

J Med Chem. 2023 Jul 27; 66(14): 9784–9796. Published online 2023 Jul 5. doi: 10.1021/acs.jmedchem.3c00590

PMCID:: PMC10388292

Abstract Article PDF–4.7M

Select item 1069871817.

Polycationic Ru(II) Luminophores: Syntheses, Photophysics, and Application in Electrostatically Driven Sensitization of Lanthanide Luminescence

Richard C. Knighton, Joseph M. Beames, Simon J. A. Pope

Inorg Chem. 2023 Dec 4; 62(48): 19446–19456. Published online 2023 Nov 20. doi: 10.1021/acs.inorgchem.3c02352

PMCID:: PMC10698718

Abstract Article PDF–3.3M

Select item 788118018.

Automatic light-adjusting electrochromic device powered by perovskite solar cell

Huan Ling, Jianchang Wu, Fengyu Su, Yanqing Tian, Yan Jun Liu

Nat Commun. 2021; 12: 1010. Published online 2021 Feb 12. doi: 10.1038/s41467-021-21086-7

PMCID:: PMC7881180

Abstract Article PDF–2.5M

Select item 39142419.

Milrinone and thyroid hormone stimulate myocardial membrane Ca2+-ATPase activity and share structural homologies.

K M Mylotte, V Cody, P J Davis, F B Davis, S D Blas, M Schoenl

Proc Natl Acad Sci U S A. 1985 Dec; 82(23): 7974–7978. doi: 10.1073/pnas.82.23.7974

PMCID:: PMC391424

Summary Page Browse PDF–885K

Select item 1084996220.

Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning

David F. Nippa, Kenneth Atz, Remo Hohler, Alex T. Müller, Andreas Marx, Christian Bartelmus, Georg Wuitschik, Irene Marzuoli, Vera Jost, Jens Wolfard, Martin Binder, Antonia F. Stepan, David B. Konrad, Uwe Grether, Rainer E. Martin, Gisbert Schneider

Nat Chem. 2024; 16(2): 239–248. Published online 2023 Nov 23. doi: 10.1038/s41557-023-01360-5

PMCID:: PMC10849962

Abstract Article PDF–1.7M

<< First< Prev

Page of 2

Next >Last >>

Supplemental Content

Filter your results:

All (37)
NIH grants (7)
Embargoed (0)

Manage Filters

PMC Images search for 3,4'-Bipyridin-2'-amine

Figure 3

Amine Landscaping to Increase Streptavidin-Conjugate Brightness
(A) Amine composition of the streptavidin mutation series, one amine: K80R, K121R, K132R, K134R; two amines: K121R, K132R, K134R; three amines: K80R, K121R; four amines: K121R; five amines: WT; six amines: N82K, R103K, K121R.
(B) Tetramer integrity of amine series, analyzed by SDS-PAGE with or without boiling and then Coomassie blue staining.
(C) Absorption spectra of amine series after labeling with 635P-NHS, normalized by the 637 nm peak.
(D) Fluorescent brightness of amine series conjugated with 635P-NHS (mean of triplicate ± 1 SD).
(E) Absorption spectra of amine series after labeling with sulfoCy3-NHS, normalized by the 553 nm peak.
(F) Fluorescent brightness of amine series conjugated with sulfoCy3-NHS (mean of triplicate ± 1 SD). See also .

Amine Landscaping to Maximize Protein-Dye Fluorescence and Ultrastable Protein-Ligand Interaction

Cell Chem Biol. 2017 Aug 17;24(8):1040-1047.e4.
FIGURE 3

Time‐dependent statistics of AREX_3pt of APT at 3.5 ppm (A), AREX_mfit of amine CEST at 2 ppm (B), AREX_poly of amine CEST at 2 ppm (C), AREX_mfit of amine CEST at 3 ppm (D), AREX_mfit of amine CEST at −2 ppm (E), and AREX_mfit of amine CEST at −3 ppm (F) in stroke lesion (red) and contralateral normal tissue (blue) (*p < .05)

Comparative evaluation of polynomial and Lorentzian lineshape‐fitted amine CEST imaging in acute ischemic stroke

Magn Reson Med. 2022 Feb;87(2):837-849.
Scheme 3Modification at Site 3, Amine Isosteres

Modifications of the amine functionality were conducted by imine formation, amide insertion and hydantoin isostere.

Discovery of Diphenyl Amine Based Sodium Channel Blockers, Effective Against hNav1.2

Bioorg Med Chem. ;14(24):8366-8378.
Fig. 5

(a) Simulated fast exchanging amine AREX (magenta) and calculated R^cest_ex (dashed black) spectra with the resonance frequency offsets of the fast exchanging amine pool at 3, 6, 12, and 21 ppm (magenta). (b) Simulated fast exchanging amine AREX spectrum with resonance frequency offset of the fast exchanging amine pool at 3 ppm (magenta) as well as AREX_mfit spectra (blue) for the fast exchanging amine and AREX_LD spectra (green). The simulated fast exchanging amine AREX spectra were created by inverse subtraction of two-pool model (fast exchanging amine and water) simulated Z-spectra and one-pool model (water) simulated Z-spectra according to , which can accurately isolate the fast exchanging amine signal from water signal. The AREX_mfit and the AREX_LD spectrum were obtained by processing the two-pool model simulated Z-spectra. Note in (a) that although the simulated fast exchanging amine AREX spectra match the R^cest_ex spectra well when their solute resonance frequency offsets are far from water resonance, they deviate significantly from the R^cest_ex spectra when their offsets are close to water resonance (arrows), indicating that the fast exchanging amine CEST signal is not a Lorentzian lineshape. Note in (b) that both the AREX_mfit and the AREX_LD cannot successfully fit the fast exchanging amine CEST signals.

Accuracy in the Quantification of Chemical Exchange Saturation Transfer (CEST) and relayed Nuclear Overhauser Enhancement (rNOE) saturation transfer effects

NMR Biomed. ;30(7):10.1002/nbm.3716.