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Select item 102491251.

5-Nitro-1,2-benzothiazol-3-amine and N-Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation

Eduardo Ramirez, Susantha K. Ganegamage, Ahmed A. Elbatrawy, Heba Alnakhala, Kazuma Shimanaka, Arati Tripathi, Sehong Min, Jean-Christophe Rochet, Ulf Dettmer, Jessica S. Fortin

ACS Omega. 2023 Jun 6; 8(22): 20102–20115. Published online 2023 May 23. doi: 10.1021/acsomega.3c02668

PMCID:: PMC10249125

Abstract Article PDF–9.7M

Select item 90582552.

1-Phenyl-N-(benzothiazol-2-yl)methanimine derivatives as Middle East respiratory syndrome coronavirus inhibitors

Min-Qi Hu, Heng Li, Ying Lin, Ying Zhang, Jie Tang, Jian-Ping Zuo, Li-Fang Yu, Xian-Kun Tong, Wei Tang, Fan Yang

RSC Adv. 2020 Nov 27; 10(71): 43299–43311. Published online 2020 Dec 7. doi: 10.1039/d0ra08442e

PMCID:: PMC9058255

Abstract Article PDF–722K

Select item 67264583.

CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax

Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth, Amarnath Natarajan

Mol Pharmacol. 2019 Oct; 96(4): 419–429. Published online 2019 Oct. doi: 10.1124/mol.119.116855

PMCID:: PMC6726458

Abstract Article PDF–1.3M

Select item 83991964.

Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents

Md. Kamrul Islam, Ah-Rum Baek, Bokyung Sung, Byeong-Woo Yang, Garam Choi, Hyun-Jin Park, Yeoun-Hee Kim, Minsup Kim, Seongmin Ha, Gang-Ho Lee, Hee-Kyung Kim, Yongmin Chang

Pharmaceuticals (Basel) 2021 Aug; 14(8): 832. Published online 2021 Aug 23. doi: 10.3390/ph14080832

PMCID:: PMC8399196

Abstract Article PDF–1.7M

Select item 76646375.

In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors

Belgin Sever, Mehlika Dilek Altıntop, Ahmet Özdemir, Gülşen Akalın Çiftçi, Doha E. Ellakwa, Hiroshi Tateishi, Mohamed O. Radwan, Mahmoud A. A. Ibrahim, Masami Otsuka, Mikako Fujita, Halil I. Ciftci, Taha F. S. Ali

Molecules. 2020 Nov; 25(21): 5190. Published online 2020 Nov 7. doi: 10.3390/molecules25215190

PMCID:: PMC7664637

Abstract Article PDF–3.6M

Select item 62371736.

Synthesis of novel 6,7-dimethoxy-4-anilinoquinolines as potent c-Met inhibitors

Qing-Wen Zhang, Zi-Dan Ye, Chang Shen, Hong-Xia Tie, Lei Wang, Lei Shi

J Enzyme Inhib Med Chem. 2019; 34(1): 124–133. Published online 2018 Nov 13. doi: 10.1080/14756366.2018.1533822

PMCID:: PMC6237173

Abstract Article PDF–1.4M

Select item 88037837.

Preclinical and clinical study on [¹⁸F]DRKXH1: a novel β-amyloid PET tracer for Alzheimer’s disease

MiaoMiao Xu, Jun Guo, JiaCheng Gu, LinLin Zhang, ZiHao Liu, Lin Ding, HongLiang Fu, YuFei Ma, Sheng Liang, Hui Wang

Eur J Nucl Med Mol Imaging. 2022; 49(2): 652–663. Published online 2021 Jul 22. doi: 10.1007/s00259-021-05421-0

PMCID:: PMC8803783

Abstract Article PDF–1.8M

Select item 42272418.

Synthesis, X-ray Structure, Spectroscopic Properties and DFT Studies of a Novel Schiff Base

Kew-Yu Chen, Hsing-Yang Tsai

Int J Mol Sci. 2014 Oct; 15(10): 18706–18724. Published online 2014 Oct 17. doi: 10.3390/ijms151018706

PMCID:: PMC4227241

Abstract Article PDF–2.2M

Select item 92289789.

The Synthesis, Characterization, Molecular Docking and In Vitro Antitumor Activity of Benzothiazole Aniline (BTA) Conjugated Metal-Salen Complexes as Non-Platinum Chemotherapeutic Agents

Md. Kamrul Islam, Seongmin Ha, Ah-Rum Baek, Byeong-Woo Yang, Yeoun-Hee Kim, Hyun-Jin Park, Minsup Kim, Sung-Wook Nam, Gang-Ho Lee, Yongmin Chang

Pharmaceuticals (Basel) 2022 Jun; 15(6): 751. Published online 2022 Jun 15. doi: 10.3390/ph15060751

PMCID:: PMC9228978

Abstract Article PDF–2.3M

Select item 380984510.

Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

Masahiro Maruyama, Hitoshi Shimada, Tetsuya Suhara, Hitoshi Shinotoh, Bin Ji, Jun Maeda, Ming-Rong Zhang, John Q. Trojanowski, Virginia M.-Y. Lee, Maiko Ono, Kazuto Masamoto, Harumasa Takano, Naruhiko Sahara, Nobuhisa Iwata, Nobuyuki Okamura, Shozo Furumoto, Yukitsuka Kudo, Qiang Chang, Takaomi C. Saido, Akihiko Takashima, Jada Lewis, Ming-Kuei Jang, Ichio Aoki, Hiroshi Ito, Makoto Higuchi

Neuron. Author manuscript; available in PMC 2014 Sep 18.

Published in final edited form as: Neuron. 2013 Sep 18; 79(6): 10.1016/j.neuron.2013.07.037. doi: 10.1016/j.neuron.2013.07.037

PMCID:: PMC3809845

Abstract Article PDF–4.9M

Select item 905359111.

Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's disease

Chandra Bhushan Mishra, Shruti Shalini, Siddharth Gusain, Amresh Prakash, Jyoti Kumari, Shikha Kumari, Anita Kumari Yadav, Andrew M. Lynn, Manisha Tiwari

RSC Adv. 2020 May 5; 10(30): 17602–17619. Published online 2020 May 5. doi: 10.1039/d0ra00663g

PMCID:: PMC9053591

Abstract Article PDF–2.9M

Select item 408989812.

Positron emission tomography radioligands for in vivo imaging of Aβ plaques

N. Scott Mason, Chester A. Mathis, William E. Klunk

J Labelled Comp Radiopharm. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: J Labelled Comp Radiopharm. 2013 Mar-Apr; 56(0): 89–95. doi: 10.1002/jlcr.2989

PMCID:: PMC4089898

Abstract Article PDF–1.7M

Select item 301827613.

Properties of New, Long Wavelength, Voltage-Sensitive Dyes in the Heart

Guy Salama, Bum-Rak Choi, Ghassan Azour, Mitra Lavasani, Vasil Tumbev, Brian M. Salzberg, Michael J. Patrick, Lauren A. Ernst, Alan S. Waggoner

J Membr Biol. Author manuscript; available in PMC 2011 Jan 10.

Published in final edited form as: J Membr Biol. 2005 Nov; 208(2): 125–140. doi: 10.1007/s00232-005-0826-8

PMCID:: PMC3018276

Abstract Article PDF–1.6M

Select item 292191714.

Characterization of the 4-(Benzothiazol-2-yl)phenylnitrenium Ion from a Putative Metabolite of a Model Anti-Tumor Drug

Mrinal Chakraborty, Kyoung Joo Jin, Stephen A Glover, Michael Novak

J Org Chem. Author manuscript; available in PMC 2011 Aug 6.

Published in final edited form as: J Org Chem. 2010 Aug 6; 75(15): 5296–5304. doi: 10.1021/jo101275y

PMCID:: PMC2921917

Abstract Article PDF–992K

Select item 878836215.

Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants

Daseul Im, Joonhong Jun, Jihyun Baek, Haejin Kim, Dahyun Kang, Hyunah Bae, Hyunwook Cho, Jung-Mi Hah

J Enzyme Inhib Med Chem. 2022; 37(1): 472–486. Published online 2022 Jan 23. doi: 10.1080/14756366.2021.2020772

PMCID:: PMC8788362

Abstract Article PDF–3.3M

Select item 633744716.

Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

Qingqiang Tian, Wen Luo, Zongjie Gan, Dan Li, Zeshu Dai, Huajun Wang, Xuetong Wang, Jianyong Yuan

Molecules. 2019 Jan; 24(1): 174. Published online 2019 Jan 4. doi: 10.3390/molecules24010174

PMCID:: PMC6337447

Abstract Article PDF–14M

Select item 1075369917.

Synthesis of Some New 1,3,4-Oxadiazole Derivatives and Evaluation of Their Anticancer Activity

Leyla Yurttaş, Asaf Evrim Evren, Aslıhan Kubilay, Mehmet Onur Aksoy, Halide Edip Temel, Gülşen Akalın Çiftçi

ACS Omega. 2023 Dec 26; 8(51): 49311–49326. Published online 2023 Dec 13. doi: 10.1021/acsomega.3c07776

PMCID:: PMC10753699

Abstract Article PDF–10M

Select item 305325418.

Synthesis and Biological Evaluation of Analogues of AKT (Protein Kinase B) Inhibitor-IV

Qi Sun, Runzhi Wu, Sutang Cai, Yuan Lin, Llewlyn Sellers, Kaori Sakamoto, Biao He, Blake R. Peterson

J Med Chem. Author manuscript; available in PMC 2012 Mar 10.

Published in final edited form as: J Med Chem. 2011 Mar 10; 54(5): 1126–1139. Published online 2011 Feb 14. doi: 10.1021/jm100912b

PMCID:: PMC3053254

Abstract Article PDF–1.3M

Select item 1035985119.

Recent advances in the synthesis of new benzothiazole based anti-tubercular compounds

Rakhi Yadav, Dilkhush Meena, Kavita Singh, Rajdeep Tyagi, Yogesh Yadav, Ram Sagar

RSC Adv. 2023 Jul 19; 13(32): 21890–21925. Published online 2023 Jul 21. doi: 10.1039/d3ra03862a

PMCID:: PMC10359851

Abstract Article PDF–7.4M

Select item 1097559320.

Novel 2-Aminobenzothiazole Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents

Omar M. Salih, Mahmoud A. Al-Sha’er, Haneen A. Basheer

ACS Omega. 2024 Mar 26; 9(12): 13928–13950. Published online 2024 Mar 14. doi: 10.1021/acsomega.3c09212

PMCID:: PMC10975593

Abstract Article PDF–7.4M

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