2,8-Dimercaptohypoxanthine - PMC

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The following term was not found in PMC: Dimercaptohypoxanthine.

Select item 94156461.

Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-a]pyridine Antileishmanial Pharmacophore

Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet, Clotilde Boudot, Emilie Brenot, Caroline Castera-Ducros, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Bertrand Courtioux, Alexis Valentin, Pierre Verhaeghe, Nadine Azas, Pascal Rathelot, Patrice Vanelle

Pharmaceuticals (Basel) 2022 Aug; 15(8): 998. Published online 2022 Aug 13. doi: 10.3390/ph15080998

PMCID:: PMC9415646

Abstract Article PDF–3.4M

Select item 92276772.

Multilevel Factors Associated With Time to Biopsy After Abnormal Screening Mammography Results by Race and Ethnicity

Marissa B. Lawson, Michael C. S. Bissell, Diana L. Miglioretti, Joanna Eavey, Christina H. Chapman, Jeanne S. Mandelblatt, Tracy Onega, Louise M. Henderson, Garth H. Rauscher, Karla Kerlikowske, Brian L. Sprague, Erin J. A. Bowles, Charlotte C. Gard, Sana Parsian, Christoph I. Lee

JAMA Oncol. 2022 Aug; 8(8): 1115–1126. Published online 2022 Jun 23. doi: 10.1001/jamaoncol.2022.1990

PMCID:: PMC9227677

Abstract Article

Select item 91695713.

Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression

Zoila A. Lopez-Bujanda, Michael C. Haffner, Matthew G. Chaimowitz, Nivedita Chowdhury, Nicholas J. Venturini, Radhika A. Patel, Aleksandar Obradovic, Corey S. Hansen, Joanna Jacków, Janielle P. Maynard, Karen S. Sfanos, Cory Abate-Shen, Charles J. Bieberich, Paula J. Hurley, Mark J. Selby, Alan J. Korman, Angela M. Christiano, Angelo M. De Marzo, Charles G. Drake

Nat Cancer. Author manuscript; available in PMC 2022 Jun 6.

Published in final edited form as: Nat Cancer. 2021 Aug; 2(8): 803–818. Published online 2021 Jul 19. doi: 10.1038/s43018-021-00227-3

PMCID:: PMC9169571

Abstract Article PDF–5.0M

Select item 113597024.

Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

James P. McKeown, Andrew J. Byrne, Sandra A. Bright, Clara E. Charleton, Shubhangi Kandwal, Ivan Čmelo, Brendan Twamley, Anthony M. McElligott, Darren Fayne, Niamh M. O’Boyle, D. Clive Williams, Mary J. Meegan

Pharmaceuticals (Basel) 2024 Aug; 17(8): 1034. Published online 2024 Aug 5. doi: 10.3390/ph17081034

PMCID:: PMC11359702

Abstract Article PDF–15M

Select item 74645595.

Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Nicolas Lebouvier, Fabrice Pagniez, Young Min Na, Da Shi, Patricia Pinson, Mathieu Marchivie, Jean Guillon, Tarek Hakki, Rita Bernhardt, Sook Wah Yee, Claire Simons, Marie-Pierre Lézé, Rolf W. Hartmann, Angélique Mularoni, Guillaume Le Baut, Isabelle Krimm, Ruben Abagyan, Patrice Le Pape, Marc Le Borgne

Pharmaceuticals (Basel) 2020 Aug; 13(8): 186. Published online 2020 Aug 8. doi: 10.3390/ph13080186

PMCID:: PMC7464559

Abstract Article PDF–5.1M

Select item 111654176.

Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis

Xinyue Zhang, Jiaye Liu, Yinyun Ni, Cheng Yi, Yiqiao Fang, Qingyang Ning, Bingbing Shen, Kaixiang Zhang, Yang Liu, Lin Yang, Kewei Li, Yong Liu, Rui Huang, Zhihui Li

JAMA Pediatr. 2024 Aug; 178(8): 800–813. Published online 2024 Jun 10. doi: 10.1001/jamapediatrics.2024.1576

PMCID:: PMC11165417

Abstract Article

Select item 99793697.

Synthesis of Difluoroarymethyl-Substituted Benzimidazo[2,1-a]isoquinolin-6(5H)-ones under Mild Conditions

Kaixia Sui, Yuting Leng, Yangjie Wu

ACS Omega. 2023 Feb 28; 8(8): 7517–7528. Published online 2023 Feb 14. doi: 10.1021/acsomega.2c06689

PMCID:: PMC9979369

Abstract Article PDF–2.1M

Select item 85733918.

Fc Binding by FcγRIIa Is Essential for Cellular Activation by the Anti-FcγRIIa mAbs 8.26 and 8.2

Bruce D. Wines, Halina M. Trist, Sandra Esparon, Rachael E. Impey, Graham A. Mackay, Robert K. Andrews, Tatiana P. Soares da Costa, Geoffrey A. Pietersz, Ross I. Baker, P. Mark Hogarth

Front Immunol. 2021; 12: 666813. Published online 2021 Oct 25. doi: 10.3389/fimmu.2021.666813

PMCID:: PMC8573391

Abstract Article PDF–10M

Select item 83898499.

Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis

Lukas E. Brümmer, Stephan Katzenschlager, Mary Gaeddert, Christian Erdmann, Stephani Schmitz, Marc Bota, Maurizio Grilli, Jan Larmann, Markus A. Weigand, Nira R. Pollock, Aurélien Macé, Sergio Carmona, Stefano Ongarello, Jilian A. Sacks, Claudia M. Denkinger

PLoS Med. 2021 Aug; 18(8): e1003735. Published online 2021 Aug 12. doi: 10.1371/journal.pmed.1003735

Correction in:: PLoS Med. 2021 Oct; 18(10): e1003825.

PMCID:: PMC8389849

Abstract Article PDF–2.1M

Select item 1057480810.

Chemistry of Carbon-Substituted Derivatives of Cobalt Bis(dicarbollide)(1⁻) Ion and Recent Progress in Boron Substitution

Lucia Pazderová, Ece Zeynep Tüzün, Dmytro Bavol, Miroslava Litecká, Lukáš Fojt, Bohumír Grűner

Molecules. 2023 Oct; 28(19): 6971. Published online 2023 Oct 7. doi: 10.3390/molecules28196971

PMCID:: PMC10574808

Abstract Article PDF–33M

Select item 886577911.

Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2⁺ macrophage differentiation

Wen-Jie Zhou, Hui-Li Yang, Jie Mei, Kai-Kai Chang, Han Lu, Zhen-Zhen Lai, Jia-Wei Shi, Xiao-Hui Wang, Ke Wu, Tao Zhang, Jian Wang, Jian-Song Sun, Jiang-Feng Ye, Da-Jin Li, Jian-Yuan Zhao, Li-Ping Jin, Ming-Qing Li

Sci Adv. 2022 Feb; 8(8): eabj2488. Published online 2022 Feb 23. doi: 10.1126/sciadv.abj2488

PMCID:: PMC8865779

Abstract Article PDF–13M

Select item 1046805612.

COVID-19 preventive social-behavioural practices and exposure to SARS-CoV-2 among residents in the city of Yaounde: Lessons from the early phase of the pandemic in Cameroon

Joseph Fokam, Alex Durand Nka, Jeremiah Efakika Gabisa, Kene Nwosu, Franck Wanda, Lucien Mama, Aude Christelle Ka’e, Yagai Bouba, Ezechiel Ngoufack Jagni Semengue, Michel Carlos Tommo Tchouaket, Désiré Takou, Aurelie minelle Kengni Ngueko, Willy Pabo, Samuel Martin Sosso, Olivia Keiser, Carlo-Federico Perno, Vittorio Colizzi, Edie-Gregory Halle Ekane, John Otshudiema Otokoye, Alexis Ndjolo, Laura Ciaffi

PLOS Glob Public Health. 2023; 3(8): e0002331. Published online 2023 Aug 30. doi: 10.1371/journal.pgph.0002331

PMCID:: PMC10468056

Abstract Article PDF–879K

Select item 1105043113.

Stereoselective Synthesis and Catalytical Application of Perillaldehyde-Based 3-Amino-1,2-diol Regioisomers

Márton Benedek Háznagy, Antal Csámpai, Imre Ugrai, Barnabás Molnár, Matti Haukka, Zsolt Szakonyi

Int J Mol Sci. 2024 Apr; 25(8): 4325. Published online 2024 Apr 13. doi: 10.3390/ijms25084325

PMCID:: PMC11050431

Abstract Article PDF–4.7M

Select item 941560814.

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

Romeo Romagnoli, Paola Oliva, Filippo Prencipe, Stefano Manfredini, Federica Budassi, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Lorenzo Manfreda, Elena Mariotto, Roberta Bortolozzi, Giampietro Viola

Pharmaceuticals (Basel) 2022 Aug; 15(8): 1031. Published online 2022 Aug 21. doi: 10.3390/ph15081031

PMCID:: PMC9415608

Abstract Article PDF–4.0M

Select item 1028703715.

Identification of pyrrolo[3’,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

Marilia Barreca, Virginia Spanò, Roberta Rocca, Roberta Bivacqua, Gianmarco Gualtieri, Maria Valeria Raimondi, Eugenio Gaudio, Roberta Bortolozzi, Lorenzo Manfreda, Ruoli Bai, Alessandra Montalbano, Stefano Alcaro, Ernest Hamel, Francesco Bertoni, Giampietro Viola, Paola Barraja

Eur J Med Chem. Author manuscript; available in PMC 2024 Jun 5.

Published in final edited form as: Eur J Med Chem. 2023 Jun 5; 254: 115372. Published online 2023 Apr 12. doi: 10.1016/j.ejmech.2023.115372

PMCID:: PMC10287037

Abstract Article PDF–1.9M

Select item 938022016.

Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells

Julian Laux, Michael Forster, Laura Riexinger, Anna Schwamborn, Jamil Guezguez, Christina Pokoj, Mark Kudolo, Lena M. Berger, Stefan Knapp, Dieter Schollmeyer, Jan Guse, Michael Burnet, Stefan A. Laufer

ACS Pharmacol Transl Sci. 2022 Aug 12; 5(8): 573–602. Published online 2022 Jul 14. doi: 10.1021/acsptsci.2c00054

PMCID:: PMC9380220

Abstract Article PDF–3.8M

Select item 941441517.

Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades

Ihab Shawish, Assem Barakat, Ali Aldalbahi, Walhan Alshaer, Fadwa Daoud, Dana A. Alqudah, Mazhar Al Zoubi, Ma’mon M. Hatmal, Mohamed S. Nafie, Matti Haukka, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham

Pharmaceutics. 2022 Aug; 14(8): 1558. Published online 2022 Jul 27. doi: 10.3390/pharmaceutics14081558

PMCID:: PMC9414415

Abstract Article PDF–13M

Select item 1144522318.

Multicenter, phase 1 study of etavopivat (FT-4202) treatment for up to 12 weeks in patients with sickle cell disease

Santosh L. Saraf, Robert Hagar, Modupe Idowu, Ifeyinwa Osunkwo, Kimberly Cruz, Frans A. Kuypers, R. Clark Brown, James Geib, Maria Ribadeneira, Patricia Schroeder, Eric Wu, Sanjeev Forsyth, Patrick F. Kelly, Theodosia A. Kalfa, Marilyn J. Telen

Blood Adv. 2024 Aug 27; 8(16): 4459–4475. Published online 2024 Apr 27. doi: 10.1182/bloodadvances.2023012467

PMCID:: PMC11445223

Abstract Article PDF–1.8M

Select item 1062101619.

Investigation of Weak Noncovalent Interactions Directed by the Amino Substituent of Pyrido- and Pyrimido-[1,2-a]benzimidazole-8,9-diones

Anastasija Gaile, Sergey Belyakov, Vit

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lijs Rjabovs, Igors Mihailovs, Baiba Turovska, Nelli Batenko

ACS Omega. 2023 Oct 31; 8(43): 40960–40971. Published online 2023 Oct 19. doi: 10.1021/acsomega.3c07005

PMCID:: PMC10621016

Abstract Article PDF–5.3M

Select item 1026784820.

Modifiability of Composite Cardiovascular Risk Associated With Chronic Kidney Disease in Type 2 Diabetes With Finerenone

Rajiv Agarwal, Bertram Pitt, Peter Rossing, Stefan D. Anker, Gerasimos Filippatos, Luis M. Ruilope, Csaba P. Kovesdy, Katherine Tuttle, Muthiah Vaduganathan, Christoph Wanner, Sameer Bansilal, Martin Gebel, Amer Joseph, Robert Lawatscheck, George L. Bakris

JAMA Cardiol. 2023 Aug; 8(8): 732–741. Published online 2023 Jun 14. doi: 10.1001/jamacardio.2023.1505

PMCID:: PMC10267848

Abstract Article

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