1-Cyclopentyl-imidazole - PMC

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 745

<< First< Prev

Page of 38

Next >Last >>

Select item 98509591.

Neutral Sphingomyelinase 2 Inhibitors Based on the 4-(1H-Imidazol-2-yl)-2,6-dialkoxyphenol scaffold

Ondrej Stepanek, Niyada Hin, Ajit G. Thomas, Ranjeet Dash, Jesse Alt, Rana Rais, Camilo Rojas, Barbara S. Slusher, Takashi Tsukamoto

Eur J Med Chem. Author manuscript; available in PMC 2023 Jan 19.

Published in final edited form as: Eur J Med Chem. 2019 May 15; 170: 276–289. Published online 2019 Mar 9. doi: 10.1016/j.ejmech.2019.03.015

PMCID:: PMC9850959

Abstract Article PDF–896K

Select item 83076982.

Imidazoles as Potential Anticancer Agents: An Update on Recent Studies

Pankaj Sharma, Chris LaRosa, Janet Antwi, Rajgopal Govindarajan, Karl A. Werbovetz

Molecules. 2021 Jul; 26(14): 4213. Published online 2021 Jul 11. doi: 10.3390/molecules26144213

PMCID:: PMC8307698

Abstract Article PDF–3.9M

Select item 36686763.

Discovery of 4-Aryl-2-benzoyl-imidazoles As Tubulin Polymerization Inhibitor with Potent Antiproliferative Properties

Min Xiao, Sunjoo Ahn, Jin Wang, Jianjun Chen, Duane. D. Miller, James T Dalton, Wei Li

J Med Chem. Author manuscript; available in PMC 2014 Apr 25.

Published in final edited form as: J Med Chem. 2013 Apr 25; 56(8): 3318–3329. Published online 2013 Apr 9. doi: 10.1021/jm4001117

PMCID:: PMC3668676

Abstract Article PDF–2.1M

Select item 91269054.

Carbene and photocatalyst-catalyzed decarboxylative radical coupling of carboxylic acids and acyl imidazoles to form ketones

Shi-Chao Ren, Xing Yang, Bivas Mondal, Chengli Mou, Weiyi Tian, Zhichao Jin, Yonggui Robin Chi

Nat Commun. 2022; 13: 2846. Published online 2022 May 23. doi: 10.1038/s41467-022-30583-2

PMCID:: PMC9126905

Abstract Article PDF–1.0M

Select item 71874135.

Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC inhibitors using fragment-based methods and structure-based design

Selena Chacón Simon, Feng Wang, Lance R. Thomas, Jason Phan, Bin Zhao, Edward T. Olejniczak, Jonathan D. Macdonald, J. Grace Shaw, Caden Schlund, William Payne, Joy Creighton, Shaun R. Stauffer, Alex G. Waterson, William P. Tansey, Stephen W. Fesik

J Med Chem. Author manuscript; available in PMC 2020 Apr 28.

Published in final edited form as: J Med Chem. 2020 Apr 23; 63(8): 4315–4333. Published online 2020 Apr 9. doi: 10.1021/acs.jmedchem.0c00224

PMCID:: PMC7187413

Abstract Article PDF–3.0M

Select item 28102236.

A Submarine Journey: The Pyrrole-Imidazole Alkaloids

Barbara Forte, Beatrice Malgesini, Claudia Piutti, Francesca Quartieri, Alessandra Scolaro, Gianluca Papeo

Mar Drugs. 2009 Dec; 7(4): 705–753. Published online 2009 Nov 27. doi: 10.3390/md7040705

PMCID:: PMC2810223

Abstract Article PDF–426K

Select item 110822507.

Carbon nanofiber/taurine-catalyzed synthesis of coumarin and 1,2,4,5-tetra-substituted imidazole derivatives under metal-free conditions

Dina Mallah, Bi Bi Fatemeh Mirjalili, Abdolhamid Bamoniri

Sci Rep. 2024; 14: 10677. Published online 2024 May 9. doi: 10.1038/s41598-024-61249-2

PMCID:: PMC11082250

Abstract Article PDF–3.9M

Select item 70844958.

Discovery of 1-Pyrimidinyl-2-Aryl-4,6-Dihydropyrrolo [3,4-d]Imidazole-5(1H)-Carboxamide as a Novel JNK Inhibitor

Miyoung Jang, Youri Oh, Hyunwook Cho, Songyi Yang, Hyungwoo Moon, Daseul Im, Jung-Mi Hah

Int J Mol Sci. 2020 Mar; 21(5): 1698. Published online 2020 Mar 2. doi: 10.3390/ijms21051698

PMCID:: PMC7084495

Abstract Article PDF–2.5M

Select item 108234689.

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Fadi Soukarieh, Alaa Mashabi, William Richardson, Eduard Vico Oton, Manuel Romero, Jean-Frédéric Dubern, Shaun N. Robertson, Simone Lucanto, Zoe Markham-Lee, Tomás Sou, Irena Kukavica-Ibrulj, Roger C. Levesque, Christel A. S. Bergstrom, Nigel Halliday, Barrie Kellam, Jonas Emsley, Stephan Heeb, Paul Williams, Michael J. Stocks, Miguel Cámara

J Med Chem. 2024 Jan 25; 67(2): 1008–1023. Published online 2024 Jan 3. doi: 10.1021/acs.jmedchem.3c00973

PMCID:: PMC10823468

Abstract Article PDF–8.5M

Select item 483629410.

Asymmetric Synthesis of Axinellamines A and B

Dr. Zhiqiang Ma, Dr. Xiao Wang, Dr. Yuyong Ma, Prof. Dr. Chuo Chen

Angew Chem Int Ed Engl. Author manuscript; available in PMC 2017 Apr 4.

Published in final edited form as: Angew Chem Int Ed Engl. 2016 Apr 4; 55(15): 4763–4766. Published online 2016 Mar 8. doi: 10.1002/anie.201600007

PMCID:: PMC4836294

Abstract Article PDF–726K

Select item 1021002411.

Synthesis, In Silico Studies, and In Vitro Anti-Inflammatory Activity of Novel Imidazole Derivatives Targeting p38 MAP Kinase

Archana Awasthi, Md Azizur Rahman, Mantripragada Bhagavan Raju

ACS Omega. 2023 May 23; 8(20): 17788–17799. Published online 2023 May 12. doi: 10.1021/acsomega.3c00605

PMCID:: PMC10210024

Abstract Article PDF–4.3M

Select item 356330112.

Toward Highly Potent Cancer Agents by Modulating the C-2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors

Giuseppe La Regina, Ruoli Bai, Whilelmina Maria Rensen, Erica Di Cesare, Antonio Coluccia, Francesco Piscitelli, Valeria Famiglini, Alessia Reggio, Marianna Nalli, Sveva Pelliccia, Eleonora Da Pozzo, Barbara Costa, Ilaria Granata, Amalia Porta, Bruno Maresca, Alessandra Soriani, Maria Luisa Iannitto, Angela Santoni, Junjie Li, Marlein Miranda Cona, Feng Chen, Yicheng Ni, Andrea Brancale, Giulio Dondio, Stefania Vultaggio, Mario Varasi, Ciro Mercurio, Claudia Martini, Ernest Hamel, Patrizia Lavia, Ettore Novellino, Romano Silvestri

J Med Chem. Author manuscript; available in PMC 2014 Jan 10.

Published in final edited form as: J Med Chem. 2013 Jan 10; 56(1): 123–149. Published online 2012 Dec 27. doi: 10.1021/jm3013097

PMCID:: PMC3563301

Abstract Article PDF–4.1M

Select item 395361713.

Selective Allosteric Enhancement of Agonist Binding and Function at Human A₃ Adenosine Receptors by a Series of Imidazoquinoline Derivatives

Zhan-Guo Gao, Seong Gon Kim, Kelly A. Soltysiak, Neli Melman, Adriaan P. Ijzerman, Kenneth A. Jacobson

Mol Pharmacol. Author manuscript; available in PMC 2014 Mar 14.

Published in final edited form as: Mol Pharmacol. 2002 Jul; 62(1): 81–89. doi: 10.1124/mol.62.1.81

PMCID:: PMC3953617

Abstract Article PDF–1.7M

Select item 607224314.

Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3

Francesco Ansideri, Joana T. Macedo, Michael Eitel, Ahmed El-Gokha, Dhafer S. Zinad, Camilla Scarpellini, Mark Kudolo, Dieter Schollmeyer, Frank M. Boeckler, Bärbel S. Blaum, Stefan A. Laufer, Pierre Koch

ACS Omega. 2018 Jul 31; 3(7): 7809–7831. Published online 2018 Jul 12. doi: 10.1021/acsomega.8b00668

PMCID:: PMC6072243

Abstract Article PDF–1.9M

Select item 827451615.

Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma

Lishun Zhang, Zichao Yang, Huiting Sang, Ying Jiang, Mingfeng Zhou, Chuan Huang, Chunhui Huang, Xiaoyun Wu, Tingting Zhang, Xingmei Zhang, Shanhe Wan, Jiajie Zhang

J Enzyme Inhib Med Chem. 2021; 36(1): 1541–1552. Published online 2021 Jul 8. doi: 10.1080/14756366.2021.1948542

PMCID:: PMC8274516

Abstract Article PDF–3.1M

Select item 422781116.

Axinellamines as Broad-Spectrum Antibacterial Agents: Scalable Synthesis and Biology

Rodrigo A. Rodriguez, Danielle Barrios Steed, Yu Kawamata, Shun Su, Peter A. Smith, Tyler C. Steed, Floyd E. Romesberg, Phil S. Baran

J Am Chem Soc. 2014 Oct 29; 136(43): 15403–15413. Published online 2014 Oct 20. doi: 10.1021/ja508632y

PMCID:: PMC4227811

Abstract Article PDF–3.2M

Select item 982626217.

Discovery of Benzo[d]imidazole‐6‐sulfonamides as Bromodomain and Extra‐Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain

Dr. Alessandra Cipriano, Prof. Ciro Milite, Dr. Alessandra Feoli, Dr. Monica Viviano, Prof. Giacomo Pepe, Prof. Pietro Campiglia, Giuliana Sarno, Dr. Sarah Picaud, Dr. Satomi Imaide, Dr. Nikolai Makukhin, Dr. Panagis Filippakopoulos, Prof. Alessio Ciulli, Prof. Sabrina Castellano, Prof. Gianluca Sbardella

ChemMedChem. 2022 Oct 19; 17(20): e202200343. Published online 2022 Sep 15. doi: 10.1002/cmdc.202200343

PMCID:: PMC9826262

Abstract Article PDF–6.9M

Select item 775619518.

Identification of 2,4-disubstituted imidazopyridines as hemozoin formation inhibitors with fast killing kinetics and in vivo efficacy in the Plasmodium falciparum NSG mouse model

André Horatscheck, Ana Andrijevic, Aloysius T. Nchinda, Claire Le Manach, Tanya Paquet, Lutete Peguy Khonde, Jean Dam, Kailash Pawar, Dale Taylor, Nina Lawrence, Christel Brunschwig, Liezl Gibhard, Mathew Njoroge, Janette Reader, Mariëtte van der Watt, Kathryn Wicht, Ana Carolina C. de Sousa, John Okombo, Keletso Maepa, Timothy J. Egan, Lyn-Marie Birkholtz, Gregory S. Basarab, Sergio Wittlin, Paul V. Fish, Leslie J. Street, James Duffy, Kelly Chibale

J Med Chem. Author manuscript; available in PMC 2021 Nov 12.

Published in final edited form as: J Med Chem. 2020 Nov 12; 63(21): 13013–13030. Published online 2020 Oct 25. doi: 10.1021/acs.jmedchem.0c01411

Correction in:: J Med Chem. 2021 Jan 28

PMCID:: PMC7756195

Abstract Article PDF–1.7M

Select item 257928419.

A role of p38 mitogen-activated protein kinase in adenosine A₁receptor-mediated synaptic depotentiation in area CA1 of the rat hippocampus

Ying-Ching Liang, Chiung-Chun Huang, Kuei-Sen Hsu

Mol Brain. 2008; 1: 13. Published online 2008 Oct 23. doi: 10.1186/1756-6606-1-13

PMCID:: PMC2579284

Abstract Article PDF–464K

Select item 366600520.

The Effect of N-Alkyl Substituents on the Usability of Imidazolium Cation-Based Ionic Liquids in Microemulsion Systems: A Technical Note

Neeraj Kumar, Shishu Goindi, Sandeep Kumar, Asim Kumar Jana

AAPS PharmSciTech. 2013 Jun; 14(2): 551–557. Published online 2013 Mar 6. doi: 10.1208/s12249-013-9939-z

PMCID:: PMC3666005

Article PDF–576K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

PMC Full-Text Search Results

Items: 1 to 20 of 745

Display Settings:

Send to:

Supplemental Content

Find related data

Search details

Recent activity