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Select item 107083601.

Resistomycin Suppresses Prostate Cancer Cell Growth by Instigating Oxidative Stress, Mitochondrial Apoptosis, and Cell Cycle Arrest

Abeer S. Aloufi, Ola A. Habotta, Mohamed S. Abdelfattah, Marina N. Habib, Mohamed M. Omran, Sally A. Ali, Ahmed E. Abdel Moneim, Shereen M. Korany, Aisha M. Alrajhi

Molecules. 2023 Dec; 28(23): 7871. Published online 2023 Nov 30. doi: 10.3390/molecules28237871

PMCID:: PMC10708360

Abstract Article PDF–3.7M

Select item 89547132.

Peptide Human Neutrophil Elastase Inhibitors from Natural Sources: An Overview

Lorenza Marinaccio, Azzurra Stefanucci, Giuseppe Scioli, Alice Della Valle, Gokhan Zengin, Angelo Cichelli, Adriano Mollica

Int J Mol Sci. 2022 Mar; 23(6): 2924. Published online 2022 Mar 8. doi: 10.3390/ijms23062924

PMCID:: PMC8954713

Abstract Article PDF–2.5M

Select item 87246043.

Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments

Meng Zhang, Liyuan Kong, Rong Gong, Marianna Iorio, Stefano Donadio, Zixin Deng, Margherita Sosio, Wenqing Chen

Microb Cell Fact. 2022; 21: 2. Published online 2022 Jan 4. doi: 10.1186/s12934-021-01722-z

PMCID:: PMC8724604

Abstract Article PDF–2.3M

Select item 69522374.

Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds

Meng Zhang, Peichao Zhang, Gudan Xu, Wenting Zhou, Yaojie Gao, Rong Gong, You-Sheng Cai, Hengjiang Cong, Zixin Deng, Neil P. J. Price, Xiangzhao Mao, Wenqing Chen

Appl Environ Microbiol. 2020 Jan; 86(2): e01971-19. Prepublished online 2019 Nov 1. Published online 2020 Jan 7. doi: 10.1128/AEM.01971-19

PMCID:: PMC6952237

Abstract Article PDF–3.1M

Select item 65604555.

Biosynthesis of Polyketides in Streptomyces

Chandra Risdian, Tjandrawati Mozef, Joachim Wink

Microorganisms. 2019 May; 7(5): 124. Published online 2019 May 6. doi: 10.3390/microorganisms7050124

PMCID:: PMC6560455

Abstract Article PDF–4.7M

Select item 53212706.

Marine Actinobacteria as a source of compounds for phytopathogen control: An integrative metabolic-profiling / bioactivity and taxonomical approach

Luz A. Betancur, Sandra J. Naranjo-Gaybor, Diana M. Vinchira-Villarraga, Nubia C. Moreno-Sarmiento, Luis A. Maldonado, Zulma R. Suarez-Moreno, Alejandro Acosta-González, Gillermo F. Padilla-Gonzalez, Mónica Puyana, Leonardo Castellanos, Freddy A. Ramos

PLoS One. 2017; 12(2): e0170148. Published online 2017 Feb 22. doi: 10.1371/journal.pone.0170148

PMCID:: PMC5321270

Abstract Article PDF–2.7M

Select item 50313347.

Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570

Houyuan Zhao, Liang Wang, Dan Wan, Jianzhao Qi, Rong Gong, Zixin Deng, Wenqing Chen

Microb Cell Fact. 2016; 15: 160. Published online 2016 Sep 21. doi: 10.1186/s12934-016-0559-7

PMCID:: PMC5031334

Abstract Article PDF–2.2M

Select item 50381368.

The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility

Toshiki G. Nakashige, Jules R. Stephan, Lisa S. Cunden, Megan Brunjes Brophy, Andrew J. Wommack, Brenna C. Keegan, Jason M. Shearer, Elizabeth M. Nolan

J Am Chem Soc. Author manuscript; available in PMC 2016 Sep 27.

Published in final edited form as: J Am Chem Soc. 2016 Sep 21; 138(37): 12243–12251. Published online 2016 Sep 7. doi: 10.1021/jacs.6b06845

PMCID:: PMC5038136

Abstract Article PDF–1.1M

Select item 49889009.

Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase

Shu-Shan Gao, Abing Duan, Wei Xu, Peiyuan Yu, Leibniz Hang, K. N. Houk, Yi Tang

J Am Chem Soc. Author manuscript; available in PMC 2017 Mar 30.

Published in final edited form as: J Am Chem Soc. 2016 Mar 30; 138(12): 4249–4259. Published online 2016 Mar 22. doi: 10.1021/jacs.6b01528

PMCID:: PMC4988900

Abstract Article PDF–2.5M

Select item 452893610.

Overproduction, crystallization and X-ray diffraction data analysis of ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis

Stefanie Kobus, Nils Widderich, Astrid Hoeppner, Erhard Bremer, Sander H. J. Smits

Acta Crystallogr F Struct Biol Commun. 2015 Aug 1; 71(Pt 8): 1027–1032. Published online 2015 Jul 28. doi: 10.1107/S2053230X15011115

PMCID:: PMC4528936

Abstract Article PDF–684K

Select item 405929111.

A primary assessment of the endophytic bacterial community in a xerophilous moss (Grimmia montana) using molecular method and cultivated isolates

Xiao Lei Liu, Su Lin Liu, Min Liu, Bi He Kong, Lei Liu, Yan Hong Li

Braz J Microbiol. 2014; 45(1): 163–173. Published online 2014 May 19. doi: 10.1590/s1517-83822014000100022

PMCID:: PMC4059291

Abstract Article PDF–937K

Select item 395816512.

Biotechnology of polyketides: New breath of life for the novel antibiotic genetic pathways discovery through metagenomics

Elisângela Soares Gomes, Viviane Schuch, Eliana Gertrudes de Macedo Lemos

Braz J Microbiol. 2013 Dec; 44(4): 1007–1034. Published online 2014 Mar 10. doi: 10.1590/s1517-83822013000400002

PMCID:: PMC3958165

Abstract Article PDF–9.0M

Select item 357977113.

Calcium Ion Gradients Modulate the Zinc Affinity and Antibacterial Activity of Human Calprotectin

Megan Brunjes Brophy, Joshua A. Hayden, Elizabeth M. Nolan

J Am Chem Soc. Author manuscript; available in PMC 2013 Oct 31.

Published in final edited form as: J Am Chem Soc. 2012 Oct 31; 134(43): 18089–18100. Published online 2012 Oct 19. doi: 10.1021/ja307974e

PMCID:: PMC3579771

Abstract Article PDF–2.0M

Select item 252915414.

Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne Biosynthesis

Steven G. Van Lanen, Tae-jin Oh, Wen Liu, Evelyn Wendt-Pienkowski, Ben Shen

J Am Chem Soc. Author manuscript; available in PMC 2008 Oct 31.

Published in final edited form as: J Am Chem Soc. 2007 Oct 31; 129(43): 13082–13094. Published online 2007 Oct 6. doi: 10.1021/ja073275o

PMCID:: PMC2529154

Abstract Article PDF–1.4M

Select item 148289415.

Utilization of the Methoxymalonyl-Acyl Carrier Protein Biosynthesis Locus for Cloning the Oxazolomycin Biosynthetic Gene Cluster from Streptomyces albus JA3453

Chunhua Zhao, Jianhua Ju, Steven D. Christenson, Wyatt C. Smith, Danfeng Song, Xiufen Zhou, Ben Shen, Zixin Deng

J Bacteriol. 2006 Jun; 188(11): 4142–4147. doi: 10.1128/JB.00173-06

PMCID:: PMC1482894

Abstract Article PDF–269K

Select item 1099049416.

Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells

Atikul Islam, Yu-Chun Chang, Xiao-Chi Chen, Chia-Wei Weng, Chien-Yu Chen, Che-Wei Wang, Mu-Kuan Chen, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh

eLife. 2024; 12: RP87873. Published online 2024 Apr 3. doi: 10.7554/eLife.87873

PMCID:: PMC10990494

Abstract Article PDF–15M

Select item 1091348317.

Identification of environmental Actinobacteria in buildings by means of chemotaxonomy, 16S rRNA sequencing, and MALDI-TOF MS

Anna Chudzik, Kaisa Jalkanen, Martin Täubel, Bogumiła Szponar, Mariola Paściak

Microbiol Spectr. 2024 Mar; 12(3): e03596-23. Published online 2024 Feb 1. doi: 10.1128/spectrum.03596-23

PMCID:: PMC10913483

Abstract Article PDF–1.1M

Select item 1039065918.

Identification and characterization of inulinases by bioinformatics analysis of bacterial glycoside hydrolases family 32 (GH32)

Fatemeh Khosravi, Ehsan Mohseni Fard, Marzieh Hosseininezhad, Hadi Shoorideh

Eng Life Sci. 2023 Aug; 23(8): e2300003. Published online 2023 Jul 9. doi: 10.1002/elsc.202300003

PMCID:: PMC10390659

Abstract Article PDF–570K

Select item 1000418219.

The Role of Natural and Semi-Synthetic Compounds in Ovarian Cancer: Updates on Mechanisms of Action, Current Trends and Perspectives

Md. Rezaul Islam, Md. Mominur Rahman, Puja Sutro Dhar, Feana Tasmim Nowrin, Nasrin Sultana, Muniya Akter, Abdur Rauf, Anees Ahmed Khalil, Alessandra Gianoncelli, Giovanni Ribaudo

Molecules. 2023 Mar; 28(5): 2070. Published online 2023 Feb 22. doi: 10.3390/molecules28052070