MeSH

An encapsulated lymphatic organ through which venous blood filters.

A species in the group RETICULOENDOTHELIOSIS VIRUSES, AVIAN of the genus GAMMARETROVIRUS originally isolated from ducks.

Year introduced: 2007

A congenital or acquired condition in which the SPLEEN is not in its normal anatomical position but moves about in the ABDOMEN. This is due to laxity or absence of suspensory ligaments which normally provide peritoneal attachments to keep the SPLEEN in a fixed position. Clinical symptoms include ABDOMINAL PAIN, splenic torsion and ISCHEMIA.

Year introduced: 2006

Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.

Year introduced: 1991(1986)

Tumors or cancer of the SPLEEN.

spleen-derived; depresses humoral response in mice

Date introduced: June 5, 1981

An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

Year introduced: 2017 (1992)

Enlargement of the spleen.

SFFV gp65 is the membrane form of SFFV gp55; has been sequenced

Date introduced: January 21, 1993

a transport-defective leukemogenic envelope glycoprotein; has been sequenced

Date introduced: December 3, 1992

differs from aprotinin by seven amino acids; has been sequenced

Date introduced: March 1, 1990

218 amino acid residues given in first source; involved in transcriptional regulation of interleukin-1beta (IL-1beta); do not confuse with proto-oncogene protein c-Spi-1 (PU.1)

Date introduced: January 18, 1990

Date introduced: January 1, 1969

A genus of ADENOVIRIDAE comprising species including viruses of frogs (FROGS AND TOADS) and TURKEYS. The type species is Frog adenovirus.

Year introduced: 2005

Insufficiency of arterial or venous blood supply to the spleen due to emboli, thrombi, vascular torsion, or pressure that produces a macroscopic area of necrosis. (From Stedman, 25th ed)

Splenic vascular neoplasms that originate in the lining of the red pulp sinuses. Most cases are benign and asymptomatic; however, they may be associated with malignant neoplasms and hematologic disorders.

Date introduced: August 25, 2010

RefSeq NM_138379

Date introduced: August 11, 2006

RefSeq NM_002263

Date introduced: August 6, 2004

RefSeq NM_004944

Date introduced: August 6, 2004

a ubiquitous monocyte protein involved in murine virus-induced acute erythroleukemias; member of ets transcription family; RefSeq NM_011355 (mouse); NM_003120 (human)

Date introduced: July 3, 1990