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Spleen
An encapsulated lymphatic organ through which venous blood filters.
Trager duck spleen necrosis virus
A species in the group RETICULOENDOTHELIOSIS VIRUSES, AVIAN of the genus GAMMARETROVIRUS originally isolated from ducks.
Year introduced: 2007
Wandering Spleen
A congenital or acquired condition in which the SPLEEN is not in its normal anatomical position but moves about in the ABDOMEN. This is due to laxity or absence of suspensory ligaments which normally provide peritoneal attachments to keep the SPLEEN in a fixed position. Clinical symptoms include ABDOMINAL PAIN, splenic torsion and ISCHEMIA.
Year introduced: 2006
Spleen Focus-Forming Viruses
Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.
Year introduced: 1991(1986)
Splenic Neoplasms
Tumors or cancer of the SPLEEN.
spleen derived immunosuppressive peptide [Supplementary Concept]
spleen-derived; depresses humoral response in mice
Date introduced: June 5, 1981
Syk Kinase
An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
Year introduced: 2017 (1992)
Splenomegaly
Enlargement of the spleen.
glycoprotein gp55, Friend spleen focus-forming virus [Supplementary Concept]
SFFV gp65 is the membrane form of SFFV gp55; has been sequenced
Date introduced: January 21, 1993
gp52 protein, spleen focus-forming virus [Supplementary Concept]
a transport-defective leukemogenic envelope glycoprotein; has been sequenced
Date introduced: December 3, 1992
spleen protease inhibitor II [Supplementary Concept]
differs from aprotinin by seven amino acids; has been sequenced
Date introduced: March 1, 1990
v-Spi-1 protein, Friend spleen focus-forming virus [Supplementary Concept]
218 amino acid residues given in first source; involved in transcriptional regulation of interleukin-1beta (IL-1beta); do not confuse with proto-oncogene protein c-Spi-1 (PU.1)
Date introduced: January 18, 1990
spleen exonuclease [Supplementary Concept]
Date introduced: January 1, 1969
Siadenovirus
A genus of ADENOVIRIDAE comprising species including viruses of frogs (FROGS AND TOADS) and TURKEYS. The type species is Frog adenovirus.
Year introduced: 2005
Splenic Infarction
Insufficiency of arterial or venous blood supply to the spleen due to emboli, thrombi, vascular torsion, or pressure that produces a macroscopic area of necrosis. (From Stedman, 25th ed)
Littoral cell angioma of the spleen [Supplementary Concept]
Splenic vascular neoplasms that originate in the lining of the red pulp sinuses. Most cases are benign and asymptomatic; however, they may be associated with malignant neoplasms and hematologic disorders.
Date introduced: August 25, 2010
TIMD4 protein, human [Supplementary Concept]
RefSeq NM_138379
Date introduced: August 11, 2006
KIFC1 protein, human [Supplementary Concept]
RefSeq NM_002263
Date introduced: August 6, 2004
DNASE1L3 protein, human [Supplementary Concept]
RefSeq NM_004944
proto-oncogene protein Spi-1 [Supplementary Concept]
a ubiquitous monocyte protein involved in murine virus-induced acute erythroleukemias; member of ets transcription family; RefSeq NM_011355 (mouse); NM_003120 (human)
Date introduced: July 3, 1990