Syk Kinase

An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

Year introduced: 2017 (1992)

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Tree Number(s): D08.811.913.696.620.682.725.650, D12.776.476.568.650

MeSH Unique ID: D000072377

Registry Number: EC 2.7.10.2

Entry Terms:

• Kinase, Syk
• SYK Tyrosine Kinase
• Kinase, SYK Tyrosine
• Tyrosine Kinase, SYK
• Spleen Tyrosine Kinase
• Kinase, Spleen Tyrosine
• Tyrosine Kinase, Spleen

See Also:

• src Homology Domains

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein-Tyrosine Kinases
Syk Kinase

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Syk Kinase