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3-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene [Supplementary Concept]
has antineoplastic activity; structure in first source
Date introduced: May 22, 2005
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Year introduced: 1975(1964)
Steroids
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Year introduced: 1963
Polycyclic Compounds
Compounds which contain two or more rings in their structure.
Year introduced: 2005(1974)
Heterocyclic Compounds, 2-Ring
A class of heterocyclic compounds that include a two-ring fused structure. Both aromatic and non-aromatic ring structures are included in this category.
Year introduced: 1998
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Benzimidazoles
Compounds with a BENZENE fused to IMIDAZOLES.
Androstenes
Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
Year introduced: 1973
Androstanes
The family of steroids from which the androgens are derived.
Year introduced: 1968
Androstadienes
Derivatives of the steroid androstane having two double bonds at any site in any of the rings.
Year introduced: 1975
Fused-Ring Compounds
Polycyclic compounds with adjacent rings that share the same two adjacent atoms.
Year introduced: 2017
Heterocyclic Compounds, Fused-Ring
Multiple ring heterocyclic compounds containing two or more rings that share two atoms and one bond in common.
Molecular Mechanisms of Pharmacological Action
Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.
Year introduced: 2008(2004)
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999