Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Year introduced: 1975(1964)

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Tree Number(s): D27.505.519.389

MeSH Unique ID: D004791

Entry Terms:

• Inhibitors, Enzyme
• Enzyme Inhibitor
• Inhibitor, Enzyme

Previous Indexing:

• Enzymes (1966-1967)
• Enzymes/antagonists and inhibitors (1968-1974)

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Molecular Mechanisms of Pharmacological Action
Enzyme Inhibitors
5-Lipoxygenase-Activating Protein Inhibitors
Acetaldehyde Dehydrogenase Inhibitors
Adenosine Deaminase Inhibitors
Adenylyl Cyclase Inhibitors
Aromatic Amino Acid Decarboxylase Inhibitors
beta-Lactamase Inhibitors
Calcineurin Inhibitors
Carbonic Anhydrase Inhibitors
Catechol O-Methyltransferase Inhibitors
Cholinesterase Inhibitors
Cyclooxygenase Inhibitors
Cyclooxygenase 2 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Cytochrome P-450 CYP2B6 Inhibitors
Cytochrome P-450 CYP2C19 Inhibitors
Cytochrome P-450 CYP2C8 Inhibitors
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2D6 Inhibitors
Cytochrome P-450 CYP2E1 Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Folic Acid Antagonists
Gamma Secretase Inhibitors and Modulators
Glycoside Hydrolase Inhibitors
Histone Deacetylase Inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Integrase Inhibitors
HIV Integrase Inhibitors
Lipoxygenase Inhibitors
Monoamine Oxidase Inhibitors
Nucleic Acid Synthesis Inhibitors
Reverse Transcriptase Inhibitors
Ornithine Decarboxylase Inhibitors
Phosphodiesterase Inhibitors
Phosphodiesterase 3 Inhibitors
Phosphodiesterase 4 Inhibitors
Phosphodiesterase 5 Inhibitors
Phosphoinositide-3 Kinase Inhibitors
Phospholipase A2 Inhibitors
Poly(ADP-ribose) Polymerase Inhibitors
Prolyl-Hydroxylase Inhibitors
Protease Inhibitors
Angiotensin-Converting Enzyme Inhibitors +
Cysteine Proteinase Inhibitors +
Dipeptidyl-Peptidase IV Inhibitors
Matrix Metalloproteinase Inhibitors
Proteasome Inhibitors
Renin Inhibitors
Serine Proteinase Inhibitors +
Viral Protease Inhibitors +
Protein Kinase Inhibitors
Janus Kinase Inhibitors
MTOR Inhibitors
Tyrosine Kinase Inhibitors
Protein Synthesis Inhibitors
Proton Pump Inhibitors
Steroid Synthesis Inhibitors
14-alpha Demethylase Inhibitors
5-alpha Reductase Inhibitors
Aromatase Inhibitors
Topoisomerase Inhibitors
Topoisomerase I Inhibitors
Topoisomerase II Inhibitors
Uncoupling Agents
Proton Ionophores