CTLA-4 Antigen

An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE.

Year introduced: 2012(1991)

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Tree Number(s): D12.776.465.782, D12.776.543.750.705.222.750, D23.050.301.264.894.158, D23.101.100.894.158

MeSH Unique ID: D060908

Entry Terms:

• Antigen, CTLA-4
• CTLA 4 Antigen
• CTLA-4 Protein
• CTLA 4 Protein
• Cytotoxic T-Lymphocyte Antigen 4
• Cytotoxic T Lymphocyte Antigen 4
• Antigens, CD152
• CD152 Antigens
• CD152 Antigen
• Antigen, CD152
• Cytotoxic T-Lymphocyte-Associated Antigen 4
• Cytotoxic T Lymphocyte Associated Antigen 4

See Also:

• Abatacept
• Ipilimumab

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Immune Checkpoint Proteins
CTLA-4 Antigen

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Receptors, Cell Surface
Receptors, Immunologic
Costimulatory and Inhibitory T-Cell Receptors
CTLA-4 Antigen

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Antigens
Antigens, Surface
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CTLA-4 Antigen

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Biomarkers
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CTLA-4 Antigen