Abatacept
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Year introduced: 2016 (2002)
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Subheadings:
Tree Number(s): D12.776.124.790.651.114.580.225, D12.776.377.715.548.114.580.225
MeSH Unique ID: D000069594
Registry Number: 7D0YB67S97
Entry Terms:
- Orencia
- BMS 188667
- BMS-188667
- BMS188667
- Belatacept
- BMS224818
- BMS-224818
- BMS 224818
- CTLA-4-Ig
- CTLA4-Ig Immunoconjugate
- CTLA4 Ig Immunoconjugate
- Immunoconjugate, CTLA4-Ig
- CTLA4-Fc
- CTLA4-Ig
- Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
- Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin
- LEA29Y
- Nulojix
See Also:
Pharmacologic Action: