Folic Acid Antagonists
Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
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Subheadings:
Tree Number(s): D27.505.519.389.350
MeSH Unique ID: D005493
Entry Terms:
- Acid Antagonists, Folic
- Antagonists, Folic Acid
- Folic Acid Antagonist
- Acid Antagonist, Folic
- Antagonist, Folic Acid
- Antifolate
- Dihydrofolate Reductase Inhibitor
- Inhibitor, Dihydrofolate Reductase
- Reductase Inhibitor, Dihydrofolate
- Antifolates
- Dihydrofolate Reductase Inhibitors
- Inhibitors, Dihydrofolate Reductase
- Reductase Inhibitors, Dihydrofolate
- Folic Acid Metabolism Inhibitors