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Reduced pancreatic beta cells
Reduced number of beta cells in the pancreatic islets of Langerhans. [from HPO]
Wolcott-Rallison dysplasia
Wolcott-Rallison syndrome is a rare autosomal recessive disorder characterized by permanent neonatal or early infancy insulin-dependent diabetes. Epiphyseal dysplasia, osteoporosis, and growth retardation develop at a later age. Other frequent multisystem manifestations include hepatic and renal dysfunction, mental retardation, and cardiovascular abnormalities (summary by Delepine et al., 2000). [from OMIM]
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