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Iris pigment dispersion
Shedding of the pigment granules that normally adhere to the back of the iris into the aqueous humor. [from HPO]
Pigment dispersion syndrome
Ocular pigment dispersion syndrome is characterized by abnormal release of iris pigment, which then accumulates within the eye, including in the trabecular meshwork, through which fluid from the eye drains. Pigment deposition is believed to increase intraocular pressure by damaging trabecular meshwork cells and decreasing aqueous humor outflow (summary by van der Heide et al., 2021). [from OMIM]
Pseudoexfoliation
Deposition of fibrillar material that can be found on all anterior segment structures bathed by aqueous humor. [from HPO]
Abnormal trabecular meshwork morphology
An anomaly of the trabecular meshwork, which is the porelike structure surrounding the entire circumference of the anterior chamber at the base of the cornea and near the ciliary body. The trabecular mesh work is responsible for draining the aqueous humor into the canal of Schlemm. [from HPO]
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