MedGen

A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [from NCI]

A type of multiple sclerosis characterized by intermittent flare-ups with a return to few or no symptoms. [from NCI]

Conditions characterized by loss or dysfunction of myelin (see myelin sheath) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or oligodendroglia associated autoantigens. [from MONDO]

A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis. [from NCI]

A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. [from NCI]

A hypersensitivity reaction type II disease that involves the central nervous system. [from MONDO]

A hypersensitivity reaction type II disease that involves the peripheral nervous system. [from MONDO]

Any condition in which there is degeneration of the myelin sheath that covers the nerves of the central nervous system. [from NCI]