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Bipolar I disorder

MedGen UID:
678499
Concept ID:
C0853193
Mental or Behavioral Dysfunction
Synonyms: Bipolar 1 disorder; bipolar 1 disorder; bipolar I disorder
SNOMED CT: Bipolar I disorder (371596008); Bipolar 1 disorder (371596008)
 
Monarch Initiative: MONDO:0001866

Definition

A bipolar disorder that is characterized by at least one manic or mixed episode. [from MONDO]

Professional guidelines

PubMed

Marzani G, Price Neff A
Am Fam Physician 2021 Feb 15;103(4):227-239. PMID: 33587568
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M
Bipolar Disord 2018 Mar;20(2):97-170. Epub 2018 Mar 14 doi: 10.1111/bdi.12609. PMID: 29536616Free PMC Article
Bobo WV
Mayo Clin Proc 2017 Oct;92(10):1532-1551. Epub 2017 Sep 6 doi: 10.1016/j.mayocp.2017.06.022. PMID: 28888714

Curated

UK NICE Clinical Guideline CG185, Bipolar disorder: assessment and management, 2023

Recent clinical studies

Etiology

Yatham LN, Arumugham SS, Kesavan M, Ramachandran K, Murthy NS, Saraf G, Ouyang Y, Bond DJ, Schaffer A, Ravindran A, Ravindran N, Frey BN, Daigneault A, Beaulieu S, Lam RW, Kondapuram N, Reddy MS, Bhandary RP, Ashok MV, Ha K, Ahn YM, Milev R, Wong H, Reddy YCJ; BEAM-BD Trial Group
N Engl J Med 2023 Aug 3;389(5):430-440. doi: 10.1056/NEJMoa2300184. PMID: 37530824
Paik J
Drugs 2021 Aug;81(12):1431-1436. doi: 10.1007/s40265-021-01568-0. PMID: 34304374
Mulayim E, Karababa İF, Akbaş H, Bayazıt H, Selek S
Arch Med Res 2021 Jul;52(5):523-528. Epub 2021 Feb 2 doi: 10.1016/j.arcmed.2021.01.002. PMID: 33546869
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M
Bipolar Disord 2018 Mar;20(2):97-170. Epub 2018 Mar 14 doi: 10.1111/bdi.12609. PMID: 29536616Free PMC Article
Bobo WV
Mayo Clin Proc 2017 Oct;92(10):1532-1551. Epub 2017 Sep 6 doi: 10.1016/j.mayocp.2017.06.022. PMID: 28888714

Diagnosis

Yatham LN, Arumugham SS, Kesavan M, Ramachandran K, Murthy NS, Saraf G, Ouyang Y, Bond DJ, Schaffer A, Ravindran A, Ravindran N, Frey BN, Daigneault A, Beaulieu S, Lam RW, Kondapuram N, Reddy MS, Bhandary RP, Ashok MV, Ha K, Ahn YM, Milev R, Wong H, Reddy YCJ; BEAM-BD Trial Group
N Engl J Med 2023 Aug 3;389(5):430-440. doi: 10.1056/NEJMoa2300184. PMID: 37530824
Marzani G, Price Neff A
Am Fam Physician 2021 Feb 15;103(4):227-239. PMID: 33587568
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M
Bipolar Disord 2018 Mar;20(2):97-170. Epub 2018 Mar 14 doi: 10.1111/bdi.12609. PMID: 29536616Free PMC Article
Bobo WV
Mayo Clin Proc 2017 Oct;92(10):1532-1551. Epub 2017 Sep 6 doi: 10.1016/j.mayocp.2017.06.022. PMID: 28888714
Sharma V, Sommerdyk C, Sharma S
Arch Womens Ment Health 2013 Apr;16(2):167-9. Epub 2013 Feb 5 doi: 10.1007/s00737-013-0328-0. PMID: 23381493

Therapy

Yatham LN, Arumugham SS, Kesavan M, Ramachandran K, Murthy NS, Saraf G, Ouyang Y, Bond DJ, Schaffer A, Ravindran A, Ravindran N, Frey BN, Daigneault A, Beaulieu S, Lam RW, Kondapuram N, Reddy MS, Bhandary RP, Ashok MV, Ha K, Ahn YM, Milev R, Wong H, Reddy YCJ; BEAM-BD Trial Group
N Engl J Med 2023 Aug 3;389(5):430-440. doi: 10.1056/NEJMoa2300184. PMID: 37530824
Harlin M, Yildirim M, Such P, Madera-McDonough J, Jan M, Jin N, Watkin S, Larsen F
CNS Drugs 2023 Apr;37(4):337-350. Epub 2023 Mar 24 doi: 10.1007/s40263-023-00996-8. PMID: 36961650Free PMC Article
Patino LR, Klein CC, Strawn JR, Blom TJ, Tallman MJ, Adler CM, Welge JA, DelBello MP
J Child Adolesc Psychopharmacol 2021 Sep;31(7):485-493. Epub 2021 Sep 14 doi: 10.1089/cap.2021.0039. PMID: 34520250Free PMC Article
Med Lett Drugs Ther 2016 Apr 25;58(1493):51-3. PMID: 27101209
Weber J, McCormack PL
CNS Drugs 2009 Sep;23(9):781-92. doi: 10.2165/11200860-000000000-00000. PMID: 19689168

Prognosis

Marzani G, Price Neff A
Am Fam Physician 2021 Feb 15;103(4):227-239. PMID: 33587568
Lamberti JS, Katsetos V, Jacobowitz DB, Weisman RL
Harv Rev Psychiatry 2020 May/Jun;28(3):179-202. doi: 10.1097/HRP.0000000000000251. PMID: 32251070
Morsel AM, Morrens M, Sabbe B
Expert Opin Pharmacother 2018 Feb;19(3):203-222. Epub 2018 Jan 23 doi: 10.1080/14656566.2018.1426746. PMID: 29361880
Iyer A, Palaniappan P
Asian J Psychiatr 2017 Dec;30:218-224. Epub 2017 May 17 doi: 10.1016/j.ajp.2017.05.012. PMID: 28559123
Johnson SL, Tharp JA, Peckham AD, McMaster KJ
J Abnorm Psychol 2016 Jan;125(1):40-52. Epub 2015 Oct 19 doi: 10.1037/abn0000116. PMID: 26480234Free PMC Article

Clinical prediction guides

Patino LR, Klein CC, Strawn JR, Blom TJ, Tallman MJ, Adler CM, Welge JA, DelBello MP
J Child Adolesc Psychopharmacol 2021 Sep;31(7):485-493. Epub 2021 Sep 14 doi: 10.1089/cap.2021.0039. PMID: 34520250Free PMC Article
Mulayim E, Karababa İF, Akbaş H, Bayazıt H, Selek S
Arch Med Res 2021 Jul;52(5):523-528. Epub 2021 Feb 2 doi: 10.1016/j.arcmed.2021.01.002. PMID: 33546869
Parker G
Australas Psychiatry 2015 Apr;23(2):112-5. Epub 2015 Feb 4 doi: 10.1177/1039856214568218. PMID: 25653300
Weber J, McCormack PL
CNS Drugs 2009 Sep;23(9):781-92. doi: 10.2165/11200860-000000000-00000. PMID: 19689168
Látalová K
Int J Clin Pract 2009 Jun;63(6):889-99. doi: 10.1111/j.1742-1241.2009.02001.x. PMID: 19490199

Recent systematic reviews

Dev DA, Le GH, Kwan ATH, Wong S, Arulmozhi A, Ceban F, Teopiz KM, Meshkat S, Rosenblat JD, Guillen-Burgos HF, Rhee TG, Ho RC, Cao B, d'Andrea G, Sundberg I, McIntyre RS
J Affect Disord 2024 Sep 15;361:480-488. Epub 2024 Jun 18 doi: 10.1016/j.jad.2024.06.045. PMID: 38901691
Mao JH, Han L, Liu XQ, Jiao Z
Expert Rev Clin Pharmacol 2023 Jan-Jun;16(6):575-588. Epub 2023 Jun 7 doi: 10.1080/17512433.2023.2219055. PMID: 37231707
Cahn AJ, Keramatian K, Frysch C, Yatham LN, Chakrabarty T
J Affect Disord 2021 Aug 1;291:198-208. Epub 2021 May 7 doi: 10.1016/j.jad.2021.04.051. PMID: 34049189
Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G
J Affect Disord 2020 May 15;269:154-184. Epub 2020 Mar 20 doi: 10.1016/j.jad.2020.03.030. PMID: 32339131
Leo RJ, Singh J
Scand J Pain 2016 Apr;11:136-145. Epub 2016 Feb 23 doi: 10.1016/j.sjpain.2015.12.002. PMID: 28850455

Supplemental Content

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    Clinical resources

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Clinical Guideline CG185, Bipolar disorder: assessment and management, 2023

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