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Items: 2

1.

Chromosome 2p16.3 deletion syndrome

Deletions at 2p16.3 involving exons of NRXN1 are associated with susceptibility to autism, schizophrenia (SCZD17), developmental delay, intellectual disability, and dysmorphic features. The phenotype is highly variable and shows incomplete penetrance (summary by Dabell et al., 2013). For a phenotypic description and a discussion of genetic heterogeneity of schizophrenia, see 181500. [from OMIM]

MedGen UID:
814824
Concept ID:
C3808494
Disease or Syndrome
2.

Pitt-Hopkins-like syndrome 2

Any Pitt-Hopkins-like syndrome in which the cause of the disease is a mutation in the NRXN1 gene. [from MONDO]

MedGen UID:
482109
Concept ID:
C3280479
Disease or Syndrome

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