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Glaucoma 1, open angle, O(GLC1O)

MedGen UID:
416515
Concept ID:
C2751294
Disease or Syndrome
Synonym: GLC1O
 
Gene (location): NTF4 (19q13.33)
 
Monarch Initiative: MONDO:0013134
OMIM®: 613100

Definition

Any open-angle glaucoma in which the cause of the disease is a mutation in the NTF4 gene. [from MONDO]

Clinical features

From HPO
Open-angle glaucoma
MedGen UID:
6611
Concept ID:
C0017612
Disease or Syndrome
A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,

Professional guidelines

PubMed

Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A, Ray K
Sci Rep 2014 May 30;4:5115. doi: 10.1038/srep05115. PMID: 24875940Free PMC Article

Curated

UK NICE Guideline NG81, Glaucoma: diagnosis and management

Recent clinical studies

Etiology

Mousa A, Kondkar AA, Al-Obeidan SA, Azad TA, Sultan T, Osman EA, Abu-Amero KK
Genet Test Mol Biomarkers 2016 Sep;20(9):556-9. Epub 2016 Aug 15 doi: 10.1089/gtmb.2016.0095. PMID: 27526043
Jakobsson C, Kheir V, Munier FL, Schorderet DF
Klin Monbl Augenheilkd 2015 Apr;232(4):427-31. Epub 2015 Apr 22 doi: 10.1055/s-0035-1545781. PMID: 25902091
Neamatzadeh H, Soleimanizad R, Atefi A, Zare-Shehneh M, Gharibi S, Shekari A, Rahimzadeh AB
Iran Biomed J 2015;19(1):51-6. doi: 10.6091/ibj.1379.2014. PMID: 25605490Free PMC Article
Costa NB, Silva CT, Frare AB, Silva RE, Moura KK
Genet Mol Res 2014 Dec 4;13(4):10382-9. doi: 10.4238/2014.December.4.33. PMID: 25501250
Lu Y, Vitart V, Burdon KP, Khor CC, Bykhovskaya Y, Mirshahi A, Hewitt AW, Koehn D, Hysi PG, Ramdas WD, Zeller T, Vithana EN, Cornes BK, Tay WT, Tai ES, Cheng CY, Liu J, Foo JN, Saw SM, Thorleifsson G, Stefansson K, Dimasi DP, Mills RA, Mountain J, Ang W, Hoehn R, Verhoeven VJ, Grus F, Wolfs R, Castagne R, Lackner KJ, Springelkamp H, Yang J, Jonasson F, Leung DY, Chen LJ, Tham CC, Rudan I, Vatavuk Z, Hayward C, Gibson J, Cree AJ, MacLeod A, Ennis S, Polasek O, Campbell H, Wilson JF, Viswanathan AC, Fleck B, Li X, Siscovick D, Taylor KD, Rotter JI, Yazar S, Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Haines JL, Kang JH, Pasquale LR, Allingham RR, Ashley-Koch A; NEIGHBOR Consortium, Mitchell P, Wang JJ, Wright AF, Pennell C, Spector TD, Young TL, Klaver CC, Martin NG, Montgomery GW, Anderson MG, Aung T, Willoughby CE, Wiggs JL, Pang CP, Thorsteinsdottir U, Lotery AJ, Hammond CJ, van Duijn CM, Hauser MA, Rabinowitz YS, Pfeiffer N, Mackey DA, Craig JE, Macgregor S, Wong TY
Nat Genet 2013 Feb;45(2):155-63. Epub 2013 Jan 6 doi: 10.1038/ng.2506. PMID: 23291589Free PMC Article

Diagnosis

Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A, Ray K
Sci Rep 2014 May 30;4:5115. doi: 10.1038/srep05115. PMID: 24875940Free PMC Article
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Therapy

Kim YW, Jeoung JW, Kim DW, Girard MJ, Mari JM, Park KH, Kim DM
PLoS One 2016;11(3):e0150260. Epub 2016 Mar 10 doi: 10.1371/journal.pone.0150260. PMID: 26963816Free PMC Article
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Prognosis

Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Clinical prediction guides

Mousa A, Kondkar AA, Al-Obeidan SA, Azad TA, Sultan T, Osman EA, Abu-Amero KK
Genet Test Mol Biomarkers 2016 Sep;20(9):556-9. Epub 2016 Aug 15 doi: 10.1089/gtmb.2016.0095. PMID: 27526043
Jakobsson C, Kheir V, Munier FL, Schorderet DF
Klin Monbl Augenheilkd 2015 Apr;232(4):427-31. Epub 2015 Apr 22 doi: 10.1055/s-0035-1545781. PMID: 25902091
Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A, Ray K
Sci Rep 2014 May 30;4:5115. doi: 10.1038/srep05115. PMID: 24875940Free PMC Article
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2022
      UK NICE Guideline NG81, Glaucoma: diagnosis and management

    Consumer resources

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