From HPO
Feeding difficulties- MedGen UID:
- 65429
- •Concept ID:
- C0232466
- •
- Finding
Impaired ability to eat related to problems gathering food and getting ready to suck, chew, or swallow it.
Hypoplasia of the cochlea- MedGen UID:
- 436824
- •Concept ID:
- C2676974
- •
- Finding
Developmental hypoplasia of the cochlea.
Profound sensorineural hearing impairment- MedGen UID:
- 868926
- •Concept ID:
- C4023338
- •
- Disease or Syndrome
Complete loss of hearing related to a sensorineural defect.
Absent internal auditory canal- MedGen UID:
- 868970
- •Concept ID:
- C4023384
- •
- Anatomical Abnormality
Aplasia of the internal auditory canal.
Self-injurious behavior- MedGen UID:
- 88371
- •Concept ID:
- C0085271
- •
- Individual Behavior
Self-aggression.
Areflexia- MedGen UID:
- 115943
- •Concept ID:
- C0234146
- •
- Finding
Absence of neurologic reflexes such as the knee-jerk reaction.
Global developmental delay- MedGen UID:
- 107838
- •Concept ID:
- C0557874
- •
- Finding
A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age.
Gait disturbance- MedGen UID:
- 107895
- •Concept ID:
- C0575081
- •
- Finding
The term gait disturbance can refer to any disruption of the ability to walk.
Autistic behavior- MedGen UID:
- 163547
- •Concept ID:
- C0856975
- •
- Mental or Behavioral Dysfunction
Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.
Insomnia- MedGen UID:
- 214589
- •Concept ID:
- C0917801
- •
- Sign or Symptom
Persistent difficulty initiating or maintaining sleep.
Sensory axonal neuropathy- MedGen UID:
- 334116
- •Concept ID:
- C1842587
- •
- Finding
An axonal neuropathy of peripheral sensory nerves.
Hyperintensity of cerebral white matter on MRI- MedGen UID:
- 811125
- •Concept ID:
- C2938912
- •
- Pathologic Function
A brighter than expected signal on magnetic resonance imaging emanating from the cerebral white matter.
Profound global developmental delay- MedGen UID:
- 766364
- •Concept ID:
- C3553450
- •
- Disease or Syndrome
A profound delay in the achievement of motor or mental milestones in the domains of development of a child.
Hyperkinetic movements- MedGen UID:
- 854367
- •Concept ID:
- C3887506
- •
- Disease or Syndrome
Motor hyperactivity with excessive movement of muscles of the body as a whole.
Myoclonic seizure- MedGen UID:
- 1385980
- •Concept ID:
- C4317123
- •
- Sign or Symptom
A myoclonic seizure is a type of motor seizure characterized by sudden, brief (<100 ms) involuntary single or multiple contraction of muscles or muscle groups of variable topography (axial, proximal limb, distal). Myoclonus is less regularly repetitive and less sustained than is clonus.
Hypotonia- MedGen UID:
- 10133
- •Concept ID:
- C0026827
- •
- Finding
Hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle). Even when relaxed, muscles have a continuous and passive partial contraction which provides some resistance to passive stretching. Hypotonia thus manifests as diminished resistance to passive stretching. Hypotonia is not the same as muscle weakness, although the two conditions can co-exist.
Flat occiput- MedGen UID:
- 332439
- •Concept ID:
- C1837402
- •
- Finding
Reduced convexity of the occiput (posterior part of skull).
Impaired mastication- MedGen UID:
- 66779
- •Concept ID:
- C0239043
- •
- Finding
An abnormal reduction in the ability to masticate (chew), i.e., in the ability to crush and ground food in preparation for swallowing.
Mask-like facies- MedGen UID:
- 140860
- •Concept ID:
- C0424448
- •
- Finding
A lack of facial expression often with staring eyes and a slightly open mouth.
Facial asymmetry- MedGen UID:
- 266298
- •Concept ID:
- C1306710
- •
- Finding
An abnormal difference between the left and right sides of the face.
Narrow palate- MedGen UID:
- 278045
- •Concept ID:
- C1398312
- •
- Finding
Width of the palate more than 2 SD below the mean (objective) or apparently decreased palatal width (subjective).
Long palpebral fissure- MedGen UID:
- 340300
- •Concept ID:
- C1849340
- •
- Finding
Distance between medial and lateral canthi is more than two standard deviations above the mean for age (objective); or, apparently increased length of the palpebral fissures.
Highly arched eyebrow- MedGen UID:
- 358357
- •Concept ID:
- C1868571
- •
- Finding
Increased height of the central portion of the eyebrow, forming a crescent, semicircular, or inverted U shape.
Ptosis- MedGen UID:
- 2287
- •Concept ID:
- C0005745
- •
- Disease or Syndrome
The upper eyelid margin is positioned 3 mm or more lower than usual and covers the superior portion of the iris (objective); or, the upper lid margin obscures at least part of the pupil (subjective).
Corneal opacity- MedGen UID:
- 40485
- •Concept ID:
- C0010038
- •
- Finding
A reduction of corneal clarity.
Absent corneal reflex- MedGen UID:
- 78835
- •Concept ID:
- C0278211
- •
- Finding
Absence of the corneal blinking reflex, which normally induces involuntary blinking of the eyelids following contact of the cornea. The corneal blink reflex is caused by a loop between the trigeminal sensory nerves and the facial motor (VII) nerve innervation of the orbicularis oculi muscles.
- Abnormality of head or neck
- Abnormality of the digestive system
- Abnormality of the eye
- Abnormality of the musculoskeletal system
- Abnormality of the nervous system
- Ear malformation