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Mirror movements 3(MRMV3)

MedGen UID:
863561
Concept ID:
C4015124
Disease or Syndrome
Synonym: MRMV3
 
Gene (location): DNAL4 (22q13.1)
 
Monarch Initiative: MONDO:0014478
OMIM®: 616059

Definition

Any familial congenital mirror movements in which the cause of the disease is a mutation in the DNAL4 gene. [from MONDO]

Clinical features

From HPO
Situs inversus
MedGen UID:
1642262
Concept ID:
C4551493
Congenital Abnormality
A left-right reversal (or mirror reflection) of the anatomical location of the major thoracic and abdominal organs.
Bimanual synkinesia
MedGen UID:
473166
Concept ID:
C0454455
Disease or Syndrome
Involuntary movements of one hand that accompany and mirror intentional movements of the opposite hand.

Professional guidelines

PubMed

Chong DST, Pople M, Hardy TJ, Cowan A, Birchley D, Guy A, McCarthy R, Welchman SA
Ann Vasc Surg 2023 Sep;95:184-187. Epub 2023 Apr 17 doi: 10.1016/j.avsg.2023.03.033. PMID: 37075833
Guémann M, Olié E, Raquin L, Courtet P, Risch N
Eur J Pain 2023 Jan;27(1):3-13. Epub 2022 Sep 19 doi: 10.1002/ejp.2035. PMID: 36094758Free PMC Article
Tavaszi I, Nagy AS, Szabo G, Fazekas G
Int J Rehabil Res 2021 Mar 1;44(1):3-14. doi: 10.1097/MRR.0000000000000438. PMID: 32991354

Recent clinical studies

Etiology

Wen X, Li L, Li X, Zha H, Liu Z, Peng Y, Liu X, Liu H, Yang Q, Wang J
Neural Plast 2022;2022:8966920. Epub 2022 Dec 31 doi: 10.1155/2022/8966920. PMID: 36624743Free PMC Article
Rajendram C, Ken-Dror G, Han T, Sharma P
BMJ Mil Health 2022 Apr;168(2):173-177. Epub 2022 Jan 18 doi: 10.1136/bmjmilitary-2021-002018. PMID: 35042760
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Zaheer A, Malik AN, Masood T, Fatima S
BMC Neurol 2021 Oct 27;21(1):416. doi: 10.1186/s12883-021-02441-z. PMID: 34706654Free PMC Article
Thieme H, Mehrholz J, Pohl M, Behrens J, Dohle C
Cochrane Database Syst Rev 2012 Mar 14;2012(3):CD008449. doi: 10.1002/14651858.CD008449.pub2. PMID: 22419334Free PMC Article

Diagnosis

Tarolli CG, Lizarraga KJ
Semin Neurol 2021 Dec;41(6):717-730. Epub 2021 Nov 26 doi: 10.1055/s-0041-1726355. PMID: 34826874
Giusti I, Di Francesco M, Dolo V
Curr Cancer Drug Targets 2017;17(3):221-235. doi: 10.2174/1568009616666160813182959. PMID: 27528364
Dunkel L, Quinton R
Eur J Endocrinol 2014 Jun;170(6):R229-39. Epub 2014 May 17 doi: 10.1530/EJE-13-0894. PMID: 24836550
Chabrier S, Husson B, Dinomais M, Landrieu P, Nguyen The Tich S
Thromb Res 2011 Jan;127(1):13-22. Epub 2010 Nov 4 doi: 10.1016/j.thromres.2010.10.003. PMID: 21055794
Szirmai I
Ideggyogy Sz 2010 Jan 30;63(1-2):13-23. PMID: 20420120

Therapy

Wen X, Li L, Li X, Zha H, Liu Z, Peng Y, Liu X, Liu H, Yang Q, Wang J
Neural Plast 2022;2022:8966920. Epub 2022 Dec 31 doi: 10.1155/2022/8966920. PMID: 36624743Free PMC Article
Zhang Y, Xing Y, Li C, Hua Y, Hu J, Wang Y, Ya R, Meng Q, Bai Y
Eur J Neurol 2022 Jan;29(1):358-371. Epub 2021 Oct 5 doi: 10.1111/ene.15122. PMID: 34558762
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Barbin J, Seetha V, Casillas JM, Paysant J, Pérennou D
Ann Phys Rehabil Med 2016 Sep;59(4):270-5. Epub 2016 May 30 doi: 10.1016/j.rehab.2016.04.001. PMID: 27256539
Thieme H, Mehrholz J, Pohl M, Behrens J, Dohle C
Cochrane Database Syst Rev 2012 Mar 14;2012(3):CD008449. doi: 10.1002/14651858.CD008449.pub2. PMID: 22419334Free PMC Article

Prognosis

Kuo HC, Ferre CL, Chin KY, Friel KM, Gordon AM
Dev Med Child Neurol 2023 Feb;65(2):264-273. Epub 2022 Jun 24 doi: 10.1111/dmcn.15322. PMID: 35751166
Murray L, Schaffner CM, Aureli F, Amici F
J Comp Psychol 2020 Aug;134(3):323-329. Epub 2020 Jun 18 doi: 10.1037/com0000243. PMID: 32551722
Spencer-Smith M, Knight JL, Lacaze E; Irc5 Consortium, Depienne C, Lockhart PJ, Richards LJ, Heron D, Leventer RJ, Robinson GA
Dev Med Child Neurol 2020 Jun;62(6):758-762. Epub 2020 Feb 14 doi: 10.1111/dmcn.14486. PMID: 32060908
Tisseyre J, Amarantini D, Chalard A, Marque P, Gasq D, Tallet J
Neuroscience 2018 May 21;379:246-256. Epub 2018 Mar 26 doi: 10.1016/j.neuroscience.2018.03.027. PMID: 29592842
Rochat P
Exp Brain Res 1998 Nov;123(1-2):102-9. doi: 10.1007/s002210050550. PMID: 9835398

Clinical prediction guides

Wen X, Li L, Li X, Zha H, Liu Z, Peng Y, Liu X, Liu H, Yang Q, Wang J
Neural Plast 2022;2022:8966920. Epub 2022 Dec 31 doi: 10.1155/2022/8966920. PMID: 36624743Free PMC Article
Rajendram C, Ken-Dror G, Han T, Sharma P
BMJ Mil Health 2022 Apr;168(2):173-177. Epub 2022 Jan 18 doi: 10.1136/bmjmilitary-2021-002018. PMID: 35042760
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Zaheer A, Malik AN, Masood T, Fatima S
BMC Neurol 2021 Oct 27;21(1):416. doi: 10.1186/s12883-021-02441-z. PMID: 34706654Free PMC Article
Thieme H, Mehrholz J, Pohl M, Behrens J, Dohle C
Cochrane Database Syst Rev 2012 Mar 14;2012(3):CD008449. doi: 10.1002/14651858.CD008449.pub2. PMID: 22419334Free PMC Article

Recent systematic reviews

Guémann M, Olié E, Raquin L, Courtet P, Risch N
Eur J Pain 2023 Jan;27(1):3-13. Epub 2022 Sep 19 doi: 10.1002/ejp.2035. PMID: 36094758Free PMC Article
Rajendram C, Ken-Dror G, Han T, Sharma P
BMJ Mil Health 2022 Apr;168(2):173-177. Epub 2022 Jan 18 doi: 10.1136/bmjmilitary-2021-002018. PMID: 35042760
Zhang Y, Xing Y, Li C, Hua Y, Hu J, Wang Y, Ya R, Meng Q, Bai Y
Eur J Neurol 2022 Jan;29(1):358-371. Epub 2021 Oct 5 doi: 10.1111/ene.15122. PMID: 34558762
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Barbin J, Seetha V, Casillas JM, Paysant J, Pérennou D
Ann Phys Rehabil Med 2016 Sep;59(4):270-5. Epub 2016 May 30 doi: 10.1016/j.rehab.2016.04.001. PMID: 27256539

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