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Psychomotor retardation

MedGen UID:
1788358
•Concept ID:
C5441816
•
Finding
Synonyms: Impairment, Psychomotor; Impairments, Psychomotor; Psychomotor Impairment; Psychomotor Impairments
SNOMED CT: Psychomotor retardation (1144814003)

Definition

Abnormally slow physical movement. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Psychomotor retardation

Professional guidelines

PubMed

Treatment of maple syrup urine disease: Benefits, risks, and challenges of liver transplantation.
Deon M, Guerreiro G, Girardi J, Ribas G, Vargas CR
Int J Dev Neurosci 2023 Oct;83(6):489-504. Epub 2023 Jun 20 doi: 10.1002/jdn.10283. PMID: 37340513
Psychomotor retardation in depression: biological underpinnings, measurement, and treatment.
Buyukdura JS, McClintock SM, Croarkin PE
Prog Neuropsychopharmacol Biol Psychiatry 2011 Mar 30;35(2):395-409. Epub 2010 Oct 31 doi: 10.1016/j.pnpbp.2010.10.019. PMID: 21044654Free PMC Article
Management of Toxoplasma gondii infection during pregnancy.
Montoya JG, Remington JS
Clin Infect Dis 2008 Aug 15;47(4):554-66. doi: 10.1086/590149. PMID: 18624630

Recent clinical studies

Etiology

Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M
J Affect Disord 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. PMID: 29407540
Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article
Psychomotor retardation in depression: a systematic review of diagnostic, pathophysiologic, and therapeutic implications.
Bennabi D, Vandel P, Papaxanthis C, Pozzo T, Haffen E
Biomed Res Int 2013;2013:158746. Epub 2013 Oct 30 doi: 10.1155/2013/158746. PMID: 24286073Free PMC Article
Allergic rhinitis.
Greiner AN, Hellings PW, Rotiroti G, Scadding GK
Lancet 2011 Dec 17;378(9809):2112-22. Epub 2011 Jul 23 doi: 10.1016/S0140-6736(11)60130-X. PMID: 21783242
Sphingolipidoses.
Yatsu FM
Calif Med 1971 Apr;114(4):1-6. PMID: 5551302Free PMC Article

Diagnosis

Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.
Wüthrich F, Nabb CB, Mittal VA, Shankman SA, Walther S
Psychol Med 2022 May;52(7):1208-1221. Epub 2022 May 13 doi: 10.1017/S0033291722000903. PMID: 35550677Free PMC Article
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M
J Affect Disord 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. PMID: 29407540
Catatonia Update.
Brar K, Kaushik SS, Lippmann S
Prim Care Companion CNS Disord 2017 Oct 26;19(5) doi: 10.4088/PCC.16br02023. PMID: 29099544
Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article
Sphingolipidoses.
Yatsu FM
Calif Med 1971 Apr;114(4):1-6. PMID: 5551302Free PMC Article

Therapy

Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.
Wüthrich F, Nabb CB, Mittal VA, Shankman SA, Walther S
Psychol Med 2022 May;52(7):1208-1221. Epub 2022 May 13 doi: 10.1017/S0033291722000903. PMID: 35550677Free PMC Article
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M
J Affect Disord 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. PMID: 29407540
Psychomotor retardation in depression: biological underpinnings, measurement, and treatment.
Buyukdura JS, McClintock SM, Croarkin PE
Prog Neuropsychopharmacol Biol Psychiatry 2011 Mar 30;35(2):395-409. Epub 2010 Oct 31 doi: 10.1016/j.pnpbp.2010.10.019. PMID: 21044654Free PMC Article
Management of Toxoplasma gondii infection during pregnancy.
Montoya JG, Remington JS
Clin Infect Dis 2008 Aug 15;47(4):554-66. doi: 10.1086/590149. PMID: 18624630
Dopamine and depression.
Brown AS, Gershon S
J Neural Transm Gen Sect 1993;91(2-3):75-109. doi: 10.1007/BF01245227. PMID: 8099801

Prognosis

Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in mood disorders.
Slavich GM, Sacher J
Psychopharmacology (Berl) 2019 Oct;236(10):3063-3079. Epub 2019 Jul 29 doi: 10.1007/s00213-019-05326-9. PMID: 31359117Free PMC Article
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M
J Affect Disord 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. PMID: 29407540
Isolated sulfite oxidase deficiency.
Claerhout H, Witters P, Régal L, Jansen K, Van Hoestenberghe MR, Breckpot J, Vermeersch P
J Inherit Metab Dis 2018 Jan;41(1):101-108. Epub 2017 Oct 4 doi: 10.1007/s10545-017-0089-4. PMID: 28980090
Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
Slavich GM, Irwin MR
Psychol Bull 2014 May;140(3):774-815. Epub 2014 Jan 13 doi: 10.1037/a0035302. PMID: 24417575Free PMC Article

Clinical prediction guides

Psychomotor semiology in depression: a standardized clinical psychomotor approach.
Paquet A, Lacroix A, Calvet B, Girard M
BMC Psychiatry 2022 Jul 15;22(1):474. doi: 10.1186/s12888-022-04086-9. PMID: 35841086Free PMC Article
Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in mood disorders.
Slavich GM, Sacher J
Psychopharmacology (Berl) 2019 Oct;236(10):3063-3079. Epub 2019 Jul 29 doi: 10.1007/s00213-019-05326-9. PMID: 31359117Free PMC Article
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri MB, Ekkekakis P, Menchetti M, Neviani F, Trevisani F, Tedeschi S, Latessa PM, Nerozzi E, Ermini G, Zocchi D, Squatrito S, Toni G, Cabassi A, Neri M, Zanetidou S, Amore M
J Affect Disord 2018 Apr 1;230:65-70. doi: 10.1016/j.jad.2018.01.004. PMID: 29407540
Isolated sulfite oxidase deficiency.
Claerhout H, Witters P, Régal L, Jansen K, Van Hoestenberghe MR, Breckpot J, Vermeersch P
J Inherit Metab Dis 2018 Jan;41(1):101-108. Epub 2017 Oct 4 doi: 10.1007/s10545-017-0089-4. PMID: 28980090
Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article

Recent systematic reviews

Motor alterations in depression and anxiety disorders: A systematic review and meta-analysis.
Elkjær E, Mikkelsen MB, Michalak J, Mennin DS, O'Toole MS
J Affect Disord 2022 Nov 15;317:373-387. Epub 2022 Aug 28 doi: 10.1016/j.jad.2022.08.060. PMID: 36037990
Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.
Wüthrich F, Nabb CB, Mittal VA, Shankman SA, Walther S
Psychol Med 2022 May;52(7):1208-1221. Epub 2022 May 13 doi: 10.1017/S0033291722000903. PMID: 35550677Free PMC Article
Psychomotor retardation in depression: a systematic review of diagnostic, pathophysiologic, and therapeutic implications.
Bennabi D, Vandel P, Papaxanthis C, Pozzo T, Haffen E
Biomed Res Int 2013;2013:158746. Epub 2013 Oct 30 doi: 10.1155/2013/158746. PMID: 24286073Free PMC Article
Treatment of infantile spasms.
Hancock EC, Osborne JP, Edwards SW
Cochrane Database Syst Rev 2013 Jun 5;(6):CD001770. doi: 10.1002/14651858.CD001770.pub3. PMID: 23740534
Treatment of infantile spasms.
Hancock E, Osborne JP, Milner P
Cochrane Database Syst Rev 2002;(2):CD001770. doi: 10.1002/14651858.CD001770. PMID: 12076419

Supplemental Content

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