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Choroidal vascular hyperpermeability

MedGen UID:
1635167
•Concept ID:
C4703391
•
Anatomical Abnormality
Synonym: Choroidal hyperpermeability
 
HPO: HP:0025570

Definition

Increased tendency of choiroidal blood vessels to allow fluids to leak characterized by multifocal choroidal hyperfluorescence on indocyanine green angiography (ICGA). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChoroidal vascular hyperpermeability

Professional guidelines

PubMed

Exploring and identifying the imaging biomarkers for predicting anti-VEGF treatment response in polypoidal choroidal vasculopathy: a prospective multicenter study.
Zhang W, Gu X, Li B, Liu S, Yang J, Wang Y, Cheng S, Lv L, Li Z, Lu L, Zhang J, Zeng Q, Xiao Z, Liu G, Xin C, Zhang T, Su Y, Chen M, Wang C, Cun Y, Zhao X, Chen Y
Ann Med 2024 Dec;56(1):2393273. Epub 2024 Aug 27 doi: 10.1080/07853890.2024.2393273. PMID: 39189520Free PMC Article
MULTIMODAL IMAGING FEATURES AND TREATMENT RESPONSES OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO CENTRAL SEROUS CHORIORETINOPATHY.
Jeong A, Kang W, Sagong M
Retina 2022 Dec 1;42(12):2326-2335. doi: 10.1097/IAE.0000000000003615. PMID: 36394887
THE INCIDENCE, CHARACTERISTICS, MANAGEMENT, PROGNOSIS, AND CLASSIFICATION OF BREAKTHROUGH VITREOUS HEMORRHAGE SECONDARY TO POLYPOIDAL CHOROIDAL VASCULOPATHY.
Zhao XY, Luo MY, Meng LH, Zhang WF, Li B, Wang EQ, Liu SZ, Yu WH, Chen YX
Retina 2021 Aug 1;41(8):1675-1685. doi: 10.1097/IAE.0000000000003098. PMID: 33395221

Recent clinical studies

Therapy

Central serous chorioretinopathy and the sclera: what we have learned so far.
Koizumi H, Imanaga N, Terao N
Jpn J Ophthalmol 2024 Sep;68(5):419-428. Epub 2024 Aug 16 doi: 10.1007/s10384-024-01101-2. PMID: 39150610Free PMC Article
Choroidal venous overload in Vogt‒Koyanagi‒Harada disease.
Noh H, Nam SW, Yoon JM, Ham DI
Eye (Lond) 2024 Oct;38(15):2960-2967. Epub 2024 Jun 29 doi: 10.1038/s41433-024-03198-8. PMID: 38951674Free PMC Article
ASSOCIATION BETWEEN CHOROIDAL CAVERNS AND CHOROIDAL VASCULAR HYPERPERMEABILITY IN EYES WITH PACHYCHOROID DISEASES.
Sakurada Y, Leong BCS, Parikh R, Fragiotta S, Freund KB
Retina 2018 Oct;38(10):1977-1983. doi: 10.1097/IAE.0000000000002294. PMID: 30198969
CHOROIDAL VASCULAR HYPERPERMEABILITY AS A PREDICTOR OF TREATMENT RESPONSE FOR POLYPOIDAL CHOROIDAL VASCULOPATHY.
Yanagi Y, Ting DSW, Ng WY, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung GCM
Retina 2018 Aug;38(8):1509-1517. doi: 10.1097/IAE.0000000000001758. PMID: 28704255
GENETIC FACTORS ASSOCIATED WITH CHOROIDAL VASCULAR HYPERPERMEABILITY AND SUBFOVEAL CHOROIDAL THICKNESS IN POLYPOIDAL CHOROIDAL VASCULOPATHY.
Yoneyama S, Sakurada Y, Kikushima W, Sugiyama A, Tanabe N, Mabuchi F, Kubota T, Iijima H
Retina 2016 Aug;36(8):1535-41. doi: 10.1097/IAE.0000000000000964. PMID: 26745149

Prognosis

Recurrence and visual prognostic factors of polypoidal choroidal vasculopathy: 5-year results.
Kim JY, Son WY, Kim RY, Kim M, Park YG, Park YH
Sci Rep 2021 Nov 3;11(1):21572. doi: 10.1038/s41598-021-00904-4. PMID: 34732787Free PMC Article
Choroidal Vascular Abnormalities by Ultra-widefield Indocyanine Green Angiography in Polypoidal Choroidal Vasculopathy.
Jeong A, Lim J, Sagong M
Invest Ophthalmol Vis Sci 2021 Feb 1;62(2):29. doi: 10.1167/iovs.62.2.29. PMID: 33605985Free PMC Article
RELATIONSHIP BETWEEN CHOROIDAL VASCULAR HYPERPERMEABILITY, CHORIOCAPILLARIS FLOW DENSITY, AND CHOROIDAL THICKNESS IN EYES WITH PACHYCHOROID PIGMENT EPITHELIOPATHY.
Sakurada Y, Fragiotta S, Leong BCS, Parikh R, Hussnain SA, Freund KB
Retina 2020 Apr;40(4):657-662. doi: 10.1097/IAE.0000000000002635. PMID: 31415450
CHOROIDAL VASCULAR HYPERPERMEABILITY AS A PREDICTOR OF TREATMENT RESPONSE FOR POLYPOIDAL CHOROIDAL VASCULOPATHY.
Yanagi Y, Ting DSW, Ng WY, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung GCM
Retina 2018 Aug;38(8):1509-1517. doi: 10.1097/IAE.0000000000001758. PMID: 28704255
Choroidal neovascularization in eyes with choroidal vascular hyperpermeability.
Miyake M, Tsujikawa A, Yamashiro K, Ooto S, Oishi A, Tamura H, Nakata I, Matsuda F, Yoshimura N
Invest Ophthalmol Vis Sci 2014 Apr 29;55(5):3223-30. doi: 10.1167/iovs.14-14059. PMID: 24781946

Clinical prediction guides

Multimodal imaging in pachychoroid spectrum.
Safi H, Ahmadieh H, Hassanpour K, Safi S
Surv Ophthalmol 2022 Mar-Apr;67(2):579-590. Epub 2021 Jul 29 doi: 10.1016/j.survophthal.2021.07.004. PMID: 34331955
Pachydrusen, choroidal vascular hyperpermeability, and punctate hyperfluorescent spots.
Kang HG, Han JY, Kim M, Byeon SH, Kim SS, Koh HJ, Lee CS
Graefes Arch Clin Exp Ophthalmol 2021 Aug;259(8):2391-2400. Epub 2021 Apr 27 doi: 10.1007/s00417-021-05180-6. PMID: 33907882
Choroidal Vascular Abnormalities by Ultra-widefield Indocyanine Green Angiography in Polypoidal Choroidal Vasculopathy.
Jeong A, Lim J, Sagong M
Invest Ophthalmol Vis Sci 2021 Feb 1;62(2):29. doi: 10.1167/iovs.62.2.29. PMID: 33605985Free PMC Article
Choroidal vascular hyperpermeability and punctate hyperfluorescent spot in choroidal neovascularization.
Kim JH, Chang YS, Lee TG, Kim CG
Invest Ophthalmol Vis Sci 2015 Feb 26;56(3):1909-15. doi: 10.1167/iovs.14-16000. PMID: 25722216
Choroidal neovascularization in eyes with choroidal vascular hyperpermeability.
Miyake M, Tsujikawa A, Yamashiro K, Ooto S, Oishi A, Tamura H, Nakata I, Matsuda F, Yoshimura N
Invest Ophthalmol Vis Sci 2014 Apr 29;55(5):3223-30. doi: 10.1167/iovs.14-14059. PMID: 24781946

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