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Breast implant-associated anaplastic large cell lymphoma

MedGen UID:
1611347
•Concept ID:
C4528210
•
Neoplastic Process
Synonyms: BIA-ALCL - breast implant-associated anaplastic large-cell lymphoma; Breast Implant-Associated Anaplastic Large Cell Lymphoma; breast implant-associated anaplastic large cell lymphoma; Breast implant-associated anaplastic large-cell lymphoma
SNOMED CT: BIA-ALCL - breast implant-associated anaplastic large-cell lymphoma (783541009); Breast implant-associated anaplastic large-cell lymphoma (783541009); Breast implant-associated anaplastic large cell lymphoma (1172730009)
 
Monarch Initiative: MONDO:0850112

Definition

A rare anaplastic large cell lymphoma that develops in individuals with breast implants. It usually presents as an accumulation of seroma fluid between the implant and the surrounding fibrous capsule. The median interval from the time of the implant to the development of lymphoma is approximately 10 years. [from NCI]

Professional guidelines

PubMed

Clinical Implications and Management of Non-BIA-ALCL Breast Implant Capsular Pathology.
Vorstenbosch J, Chu JJ, Ariyan CE, McCarthy CM, Disa JJ, Nelson JA
Plast Reconstr Surg 2023 Jan 1;151(1):20e-30e. Epub 2022 Oct 4 doi: 10.1097/PRS.0000000000009780. PMID: 36194076Free PMC Article
Clinical recommendations for diagnosis and treatment according to current updated knowledge on BIA-ALCL.
Longo B, Di Napoli A, Curigliano G, Veronesi P, Pileri S, Martelli M, De Vita R, Felici N, Cirillo P, Bernardi C, D'orsi G, Giacalone M, Storti G, Cervelli V
Breast 2022 Dec;66:332-341. Epub 2022 Dec 3 doi: 10.1016/j.breast.2022.11.009. PMID: 36502569Free PMC Article
ACR Appropriateness Criteria(®) Breast Implant Evaluation.
Expert Panel on Breast Imaging:, Lourenco AP, Moy L, Baron P, Didwania AD, diFlorio RM, Heller SL, Holbrook AI, Lewin AA, Mehta TS, Niell BL, Slanetz PJ, Stuckey AR, Tuscano DS, Vincoff NS, Weinstein SP, Newell MS
J Am Coll Radiol 2018 May;15(5S):S13-S25. doi: 10.1016/j.jacr.2018.03.009. PMID: 29724416

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), T-Cell Lymphomas, 2024

Recent clinical studies

Etiology

Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
Breast Implant-associated Anaplastic Large Cell Lymphoma.
Alotaibi S, Hamadani M, Al-Mansour M, Aljurf M
Clin Lymphoma Myeloma Leuk 2021 Mar;21(3):e272-e276. Epub 2020 Dec 13 doi: 10.1016/j.clml.2020.12.005. PMID: 33384263
Breast implant-associated anaplastic large cell lymphoma: A comprehensive review.
Marra A, Viale G, Pileri SA, Pravettoni G, Viale G, De Lorenzi F, Nolè F, Veronesi P, Curigliano G
Cancer Treat Rev 2020 Mar;84:101963. Epub 2020 Jan 13 doi: 10.1016/j.ctrv.2020.101963. PMID: 31958739
Breast Implant-Associated Anaplastic Large Cell Lymphoma.
Ashar BS, Yoon SW, Nagel S
Am Fam Physician 2020 Jan 1;101(1):8-9. PMID: 31894932
Breast Implant-Associated Anaplastic Large Cell Lymphoma and Textured Breast Implants.
Lineaweaver WC
Ann Plast Surg 2019 Jun;82(6):595-596. doi: 10.1097/SAP.0000000000001964. PMID: 31082846

Diagnosis

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Updates in Diagnosis and Specimen Handling.
Marques-Piubelli ML, Medeiros LJ, Stewart J, Miranda RN
Surg Pathol Clin 2023 Jun;16(2):347-360. Epub 2023 Mar 10 doi: 10.1016/j.path.2023.01.003. PMID: 37149362
Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
Breast-implant-associated anaplastic large-cell lymphoma.
Ozalla Samaniego S, Meijide Santos G, Soto Dopazo M, Baldó Sierra C
Radiologia (Engl Ed) 2022 Mar;64 Suppl 1:44-48. doi: 10.1016/j.rxeng.2020.10.010. PMID: 35428467
Breast implant-associated anaplastic large cell lymphoma: A comprehensive review.
Marra A, Viale G, Pileri SA, Pravettoni G, Viale G, De Lorenzi F, Nolè F, Veronesi P, Curigliano G
Cancer Treat Rev 2020 Mar;84:101963. Epub 2020 Jan 13 doi: 10.1016/j.ctrv.2020.101963. PMID: 31958739
Breast Implant-Associated Anaplastic Large Cell Lymphoma.
Ashar BS, Yoon SW, Nagel S
Am Fam Physician 2020 Jan 1;101(1):8-9. PMID: 31894932

Therapy

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Updates in Diagnosis and Specimen Handling.
Marques-Piubelli ML, Medeiros LJ, Stewart J, Miranda RN
Surg Pathol Clin 2023 Jun;16(2):347-360. Epub 2023 Mar 10 doi: 10.1016/j.path.2023.01.003. PMID: 37149362
Breast-implant-associated anaplastic large-cell lymphoma.
Ozalla Samaniego S, Meijide Santos G, Soto Dopazo M, Baldó Sierra C
Radiologia (Engl Ed) 2022 Mar;64 Suppl 1:44-48. doi: 10.1016/j.rxeng.2020.10.010. PMID: 35428467
Breast Implant-associated Anaplastic Large Cell Lymphoma.
Alotaibi S, Hamadani M, Al-Mansour M, Aljurf M
Clin Lymphoma Myeloma Leuk 2021 Mar;21(3):e272-e276. Epub 2020 Dec 13 doi: 10.1016/j.clml.2020.12.005. PMID: 33384263
Breast Implant-associated Anaplastic Large Cell Lymphoma: Review and Multiparametric Imaging Paradigms.
Sharma B, Jurgensen-Rauch A, Pace E, Attygalle AD, Sharma R, Bommier C, Wotherspoon AC, Sharma S, Iyengar S, El-Sharkawi D
Radiographics 2020 May-Jun;40(3):609-628. Epub 2020 Apr 17 doi: 10.1148/rg.2020190198. PMID: 32302264
Breast Implant-Associated Anaplastic Large Cell Lymphoma.
Ashar BS, Yoon SW, Nagel S
Am Fam Physician 2020 Jan 1;101(1):8-9. PMID: 31894932

Prognosis

Breast-implant-associated anaplastic large-cell lymphoma.
Ozalla Samaniego S, Meijide Santos G, Soto Dopazo M, Baldó Sierra C
Radiologia (Engl Ed) 2022 Mar;64 Suppl 1:44-48. doi: 10.1016/j.rxeng.2020.10.010. PMID: 35428467
Breast Implant-associated Anaplastic Large Cell Lymphoma.
Alotaibi S, Hamadani M, Al-Mansour M, Aljurf M
Clin Lymphoma Myeloma Leuk 2021 Mar;21(3):e272-e276. Epub 2020 Dec 13 doi: 10.1016/j.clml.2020.12.005. PMID: 33384263
Breast Implant-associated Anaplastic Large Cell Lymphoma: Review and Multiparametric Imaging Paradigms.
Sharma B, Jurgensen-Rauch A, Pace E, Attygalle AD, Sharma R, Bommier C, Wotherspoon AC, Sharma S, Iyengar S, El-Sharkawi D
Radiographics 2020 May-Jun;40(3):609-628. Epub 2020 Apr 17 doi: 10.1148/rg.2020190198. PMID: 32302264
Breast implant-associated anaplastic large cell lymphoma: A comprehensive review.
Marra A, Viale G, Pileri SA, Pravettoni G, Viale G, De Lorenzi F, Nolè F, Veronesi P, Curigliano G
Cancer Treat Rev 2020 Mar;84:101963. Epub 2020 Jan 13 doi: 10.1016/j.ctrv.2020.101963. PMID: 31958739
Breast Implant-Associated Anaplastic Large Cell Lymphoma and Textured Breast Implants.
Lineaweaver WC
Ann Plast Surg 2019 Jun;82(6):595-596. doi: 10.1097/SAP.0000000000001964. PMID: 31082846

Clinical prediction guides

Breast implant associated EBV-positive Diffuse Large B-cell lymphoma: an underrecognized entity?
Vets J, Marcelis L, Schepers C, Dorreman Y, Verbeek S, Vanwalleghem L, Gieraerts K, Meylaerts L, Lesaffer J, Devos H, Put N, Snauwaert S, De Paepe P, Tousseyn T
Diagn Pathol 2023 Apr 25;18(1):52. doi: 10.1186/s13000-023-01337-5. PMID: 37098615Free PMC Article
Breast Implant-Associated Anaplastic Large-Cell Lymphoma in Brazil: What Are We Missing?
Groth AK, Clemens MW, Graf R, Sebastião AP, Azambuja AP, Louveira MH, Urban LABD, Batista BN
Plast Reconstr Surg 2022 Nov 1;150(5):970e-978e. Epub 2022 Aug 22 doi: 10.1097/PRS.0000000000009652. PMID: 35994334
Is Breast Implant Associated-Anaplastic Large Cell Lymphoma linked to textured implants?
Nava MB, Chiodini P, Catanuto G, Rocco N
Aesthetic Plast Surg 2021 Dec;45(6):2593-2601. Epub 2021 Apr 9 doi: 10.1007/s00266-021-02260-0. PMID: 33837459
Breast Implant-associated Anaplastic Large Cell Lymphoma: Review and Multiparametric Imaging Paradigms.
Sharma B, Jurgensen-Rauch A, Pace E, Attygalle AD, Sharma R, Bommier C, Wotherspoon AC, Sharma S, Iyengar S, El-Sharkawi D
Radiographics 2020 May-Jun;40(3):609-628. Epub 2020 Apr 17 doi: 10.1148/rg.2020190198. PMID: 32302264
CD30+ T-cell lymphoproliferative disorders.
Martin JM, Wu H, Barta SK
Chin Clin Oncol 2019 Feb;8(1):4. Epub 2018 Oct 11 doi: 10.21037/cco.2018.09.06. PMID: 30525751

Recent systematic reviews

Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma in the United States: A Systematic Review.
Santanelli di Pompeo F, Clemens MW, Paolini G, Firmani G, Panagiotakos D, Sorotos M
Aesthet Surg J 2023 Dec 14;44(1):NP32-NP40. doi: 10.1093/asj/sjad279. PMID: 37616552
Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Updated Systematic Review and Analysis of Treatment Strategies.
Naga HI, Mellia JA, Basta MN, Morris MP, Christopher AN, Campbell FM, Sommers K, Levinson H, Nelson JA, Fischer JP
Plast Reconstr Surg 2022 Oct 1;150(4):762-769. Epub 2022 Jul 22 doi: 10.1097/PRS.0000000000009538. PMID: 35862104Free PMC Article
Breast Implant-associated Anaplastic Large Cell Lymphoma: An Evidence-based Systematic Review.
DeCoster RC, Lynch EB, Bonaroti AR, Webster JM, Butterfield TA, Evers BM, Vasconez HC, Clemens MW
Ann Surg 2021 Mar 1;273(3):449-458. doi: 10.1097/SLA.0000000000004365. PMID: 33234792
Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Systematic Review.
Leberfinger AN, Behar BJ, Williams NC, Rakszawski KL, Potochny JD, Mackay DR, Ravnic DJ
JAMA Surg 2017 Dec 1;152(12):1161-1168. doi: 10.1001/jamasurg.2017.4026. PMID: 29049466
Breast implant-associated anaplastic large cell lymphoma: a systematic review.
Gidengil CA, Predmore Z, Mattke S, van Busum K, Kim B
Plast Reconstr Surg 2015 Mar;135(3):713-720. doi: 10.1097/PRS.0000000000001037. PMID: 25490539

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    Clinical resources

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), T-Cell Lymphomas, 2024

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    Reviews

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