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Pneumonia caused by Gram positive bacteria

MedGen UID:
1379201
•Concept ID:
C4518562
•
Disease or Syndrome
Synonym: Gram positive pneumonia
SNOMED CT: Pneumonia caused by Gram positive bacteria (733051000); Gram positive pneumonia (733051000)

Professional guidelines

PubMed

Bacterial Conjunctivitis in Childhood: Etiology, Clinical Manifestations, Diagnosis, and Management.
Leung AKC, Hon KL, Wong AHC, Wong AS
Recent Pat Inflamm Allergy Drug Discov 2018;12(2):120-127. doi: 10.2174/1872213X12666180129165718. PMID: 29380707
Treatment of Staphylococcus aureus Infections.
David MZ, Daum RS
Curr Top Microbiol Immunol 2017;409:325-383. doi: 10.1007/82_2017_42. PMID: 28900682
Pathogenesis, treatment, and prevention of pneumococcal pneumonia.
van der Poll T, Opal SM
Lancet 2009 Oct 31;374(9700):1543-56. doi: 10.1016/S0140-6736(09)61114-4. PMID: 19880020

Recent clinical studies

Etiology

Bloodstream infections in adult patients with malignancy, epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance.
Amanati A, Sajedianfard S, Khajeh S, Ghasempour S, Mehrangiz S, Nematolahi S, Shahhosein Z
BMC Infect Dis 2021 Jul 2;21(1):636. doi: 10.1186/s12879-021-06243-z. PMID: 34215207Free PMC Article
Bacterial co-infections with SARS-CoV-2.
Mirzaei R, Goodarzi P, Asadi M, Soltani A, Aljanabi HAA, Jeda AS, Dashtbin S, Jalalifar S, Mohammadzadeh R, Teimoori A, Tari K, Salari M, Ghiasvand S, Kazemi S, Yousefimashouf R, Keyvani H, Karampoor S
IUBMB Life 2020 Oct;72(10):2097-2111. Epub 2020 Aug 8 doi: 10.1002/iub.2356. PMID: 32770825Free PMC Article
Pneumonia mortality, comorbidities matter?
Hespanhol V, Bárbara C
Pulmonology 2020 May-Jun;26(3):123-129. Epub 2019 Nov 29 doi: 10.1016/j.pulmoe.2019.10.003. PMID: 31787563
Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking, diabetes, and/or chronic heart disease on community-acquired pneumonia and invasive pneumococcal disease.
Torres A, Blasi F, Dartois N, Akova M
Thorax 2015 Oct;70(10):984-9. Epub 2015 Jul 28 doi: 10.1136/thoraxjnl-2015-206780. PMID: 26219979Free PMC Article
Pneumonia in the immunocompetent patient.
Reynolds JH, McDonald G, Alton H, Gordon SB
Br J Radiol 2010 Dec;83(996):998-1009. doi: 10.1259/bjr/31200593. PMID: 21088086Free PMC Article

Diagnosis

Infectious Pulmonary Diseases.
Rafeq R, Igneri LA
Infect Dis Clin North Am 2024 Mar;38(1):1-17. doi: 10.1016/j.idc.2023.12.006. PMID: 38280758
Linezolid: a review of its properties, function, and use in critical care.
Hashemian SMR, Farhadi T, Ganjparvar M
Drug Des Devel Ther 2018;12:1759-1767. Epub 2018 Jun 18 doi: 10.2147/DDDT.S164515. PMID: 29950810Free PMC Article
Community-acquired pneumonia.
José RJ, Periselneris JN, Brown JS
Curr Opin Pulm Med 2015 May;21(3):212-8. doi: 10.1097/MCP.0000000000000150. PMID: 25775050
Pneumonia in the immunocompetent patient.
Reynolds JH, McDonald G, Alton H, Gordon SB
Br J Radiol 2010 Dec;83(996):998-1009. doi: 10.1259/bjr/31200593. PMID: 21088086Free PMC Article
Pathogenesis, treatment, and prevention of pneumococcal pneumonia.
van der Poll T, Opal SM
Lancet 2009 Oct 31;374(9700):1543-56. doi: 10.1016/S0140-6736(09)61114-4. PMID: 19880020

Therapy

Ceftaroline.
Soriano A
Rev Esp Quimioter 2021 Sep;34 Suppl 1(Suppl1):29-31. Epub 2021 Sep 30 doi: 10.37201/req/s01.08.2021. PMID: 34598420Free PMC Article
Bloodstream infections in adult patients with malignancy, epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance.
Amanati A, Sajedianfard S, Khajeh S, Ghasempour S, Mehrangiz S, Nematolahi S, Shahhosein Z
BMC Infect Dis 2021 Jul 2;21(1):636. doi: 10.1186/s12879-021-06243-z. PMID: 34215207Free PMC Article
Bacterial co-infections with SARS-CoV-2.
Mirzaei R, Goodarzi P, Asadi M, Soltani A, Aljanabi HAA, Jeda AS, Dashtbin S, Jalalifar S, Mohammadzadeh R, Teimoori A, Tari K, Salari M, Ghiasvand S, Kazemi S, Yousefimashouf R, Keyvani H, Karampoor S
IUBMB Life 2020 Oct;72(10):2097-2111. Epub 2020 Aug 8 doi: 10.1002/iub.2356. PMID: 32770825Free PMC Article
Evolving Understanding of the Causes of Pneumonia in Adults, With Special Attention to the Role of Pneumococcus.
Musher DM, Abers MS, Bartlett JG
Clin Infect Dis 2017 Oct 30;65(10):1736-1744. doi: 10.1093/cid/cix549. PMID: 29028977Free PMC Article
Pathogenesis, treatment, and prevention of pneumococcal pneumonia.
van der Poll T, Opal SM
Lancet 2009 Oct 31;374(9700):1543-56. doi: 10.1016/S0140-6736(09)61114-4. PMID: 19880020

Prognosis

Pneumonia mortality, comorbidities matter?
Hespanhol V, Bárbara C
Pulmonology 2020 May-Jun;26(3):123-129. Epub 2019 Nov 29 doi: 10.1016/j.pulmoe.2019.10.003. PMID: 31787563
Bacterial Infections in Acute-on-Chronic Liver Failure.
Yang L, Wu T, Li J, Li J
Semin Liver Dis 2018 May;38(2):121-133. Epub 2018 Jun 5 doi: 10.1055/s-0038-1657751. PMID: 29871019
Pneumonia and Streptococcus pneumoniae vaccine.
Kim GL, Seon SH, Rhee DK
Arch Pharm Res 2017 Aug;40(8):885-893. Epub 2017 Jul 22 doi: 10.1007/s12272-017-0933-y. PMID: 28735461Free PMC Article
Pneumococcal infection in adults: burden of disease.
Drijkoningen JJ, Rohde GG
Clin Microbiol Infect 2014 May;20 Suppl 5:45-51. Epub 2014 Jan 24 doi: 10.1111/1469-0691.12461. PMID: 24313448
Pathogenesis, treatment, and prevention of pneumococcal pneumonia.
van der Poll T, Opal SM
Lancet 2009 Oct 31;374(9700):1543-56. doi: 10.1016/S0140-6736(09)61114-4. PMID: 19880020

Clinical prediction guides

Ceftaroline.
Soriano A
Rev Esp Quimioter 2021 Sep;34 Suppl 1(Suppl1):29-31. Epub 2021 Sep 30 doi: 10.37201/req/s01.08.2021. PMID: 34598420Free PMC Article
Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of Gram-negative nosocomial pneumonia (APEKS-NP): a randomised, double-blind, phase 3, non-inferiority trial.
Wunderink RG, Matsunaga Y, Ariyasu M, Clevenbergh P, Echols R, Kaye KS, Kollef M, Menon A, Pogue JM, Shorr AF, Timsit JF, Zeitlinger M, Nagata TD
Lancet Infect Dis 2021 Feb;21(2):213-225. Epub 2020 Oct 12 doi: 10.1016/S1473-3099(20)30731-3. PMID: 33058798
Global etiology of bacterial meningitis: A systematic review and meta-analysis.
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
Iclaprim.
Kohlhoff SA, Sharma R
Expert Opin Investig Drugs 2007 Sep;16(9):1441-8. doi: 10.1517/13543784.16.9.1441. PMID: 17714029

Recent systematic reviews

Risk Factors for Nontuberculous Mycobacterial Pulmonary Disease: A Systematic Literature Review and Meta-Analysis.
Loebinger MR, Quint JK, van der Laan R, Obradovic M, Chawla R, Kishore A, van Ingen J
Chest 2023 Nov;164(5):1115-1124. Epub 2023 Jun 17 doi: 10.1016/j.chest.2023.06.014. PMID: 37429481
Ceftaroline: Systematic Review of Clinical Uses and Emerging Drug Resistance.
Abate G, Wang G, Frisby J
Ann Pharmacother 2022 Dec;56(12):1339-1348. Epub 2022 Mar 18 doi: 10.1177/10600280221082326. PMID: 35300514
Global etiology of bacterial meningitis: A systematic review and meta-analysis.
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.
Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, Dugas A
Influenza Other Respir Viruses 2016 Sep;10(5):394-403. Epub 2016 Jun 24 doi: 10.1111/irv.12398. PMID: 27232677Free PMC Article
Community-acquired pneumonia.
Loeb M
BMJ Clin Evid 2010 Aug 18;2010 PMID: 21418681Free PMC Article

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