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Epileptic seizure

MedGen UID:
1382425
•Concept ID:
C4317109
•
Disease or Syndrome
Synonyms: Epileptic Seizure; Epileptic Seizures; Seizure, Epileptic; Seizures, Epileptic
SNOMED CT: Epileptic convulsion (313307000); Epileptic seizure (313307000)

Definition

A transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain, regardless of whether focal, generalized, or unknown onset, whether aware or impaired awareness, and whether motor or nonmotor. [from SNOMEDCT_US]

Professional guidelines

PubMed

Emergency management of epileptic seizures: a consensus statement.
García Morales I, Fernández Alonso C, Behzadi Koochani N, Serratosa Fernández JM, Gil-Nagel Rein A, Toledo M, González FJ, Santamarina Pérez E
Emergencias 2020 Oct;32(5):353-362. PMID: 33006837
Management of psychogenic non-epileptic seizures: a multidisciplinary approach.
Gasparini S, Beghi E, Ferlazzo E, Beghi M, Belcastro V, Biermann KP, Bottini G, Capovilla G, Cervellione RA, Cianci V, Coppola G, Cornaggia CM, De Fazio P, De Masi S, De Sarro G, Elia M, Erba G, Fusco L, Gambardella A, Gentile V, Giallonardo AT, Guerrini R, Ingravallo F, Iudice A, Labate A, Lucenteforte E, Magaudda A, Mumoli L, Papagno C, Pesce GB, Pucci E, Ricci P, Romeo A, Quintas R, Sueri C, Vitaliti G, Zoia R, Aguglia U
Eur J Neurol 2019 Feb;26(2):205-e15. Epub 2018 Nov 29 doi: 10.1111/ene.13818. PMID: 30300463
Anesthesia-induced epilepsy: causes and treatment.
Zhao X, Wang X
Expert Rev Neurother 2014 Sep;14(9):1099-113. Epub 2014 Aug 13 doi: 10.1586/14737175.2014.948851. PMID: 25115173

Recent clinical studies

Therapy

Schizophrenia and epileptic comorbidity.
Drapier D
Rev Neurol (Paris) 2024 Apr;180(4):308-313. Epub 2024 Mar 19 doi: 10.1016/j.neurol.2024.03.002. PMID: 38503587
Prognosis of adults and children following a first unprovoked seizure.
Neligan A, Adan G, Nevitt SJ, Pullen A, Sander JW, Bonnett L, Marson AG
Cochrane Database Syst Rev 2023 Jan 23;1(1):CD013847. doi: 10.1002/14651858.CD013847.pub2. PMID: 36688481Free PMC Article
Cannabidiol in canine epilepsy.
Potschka H, Bhatti SFM, Tipold A, McGrath S
Vet J 2022 Dec;290:105913. Epub 2022 Oct 6 doi: 10.1016/j.tvjl.2022.105913. PMID: 36209995
Antiseizure Medications for Adults With Epilepsy: A Review.
Kanner AM, Bicchi MM
JAMA 2022 Apr 5;327(13):1269-1281. doi: 10.1001/jama.2022.3880. PMID: 35380580
Autoantibody-Mediated Encephalitis.
Wandinger KP, Leypoldt F, Junker R
Dtsch Arztebl Int 2018 Nov 5;115(40):666-673. doi: 10.3238/arztebl.2018.0666. PMID: 30381132Free PMC Article

Prognosis

Prognosis of adults and children following a first unprovoked seizure.
Neligan A, Adan G, Nevitt SJ, Pullen A, Sander JW, Bonnett L, Marson AG
Cochrane Database Syst Rev 2023 Jan 23;1(1):CD013847. doi: 10.1002/14651858.CD013847.pub2. PMID: 36688481Free PMC Article
Diffuse Low-Grade Glioma-Related Epilepsy.
Pallud J, McKhann GM
Neurosurg Clin N Am 2019 Jan;30(1):43-54. Epub 2018 Nov 1 doi: 10.1016/j.nec.2018.09.001. PMID: 30470404
Patterns of epileptic seizure occurrence.
Amengual-Gual M, Sánchez Fernández I, Loddenkemper T
Brain Res 2019 Jan 15;1703:3-12. Epub 2018 Feb 23 doi: 10.1016/j.brainres.2018.02.032. PMID: 29481793
Autoantibody-Mediated Encephalitis.
Wandinger KP, Leypoldt F, Junker R
Dtsch Arztebl Int 2018 Nov 5;115(40):666-673. doi: 10.3238/arztebl.2018.0666. PMID: 30381132Free PMC Article
Anesthesia-induced epilepsy: causes and treatment.
Zhao X, Wang X
Expert Rev Neurother 2014 Sep;14(9):1099-113. Epub 2014 Aug 13 doi: 10.1586/14737175.2014.948851. PMID: 25115173

Clinical prediction guides

Prognosis of adults and children following a first unprovoked seizure.
Neligan A, Adan G, Nevitt SJ, Pullen A, Sander JW, Bonnett L, Marson AG
Cochrane Database Syst Rev 2023 Jan 23;1(1):CD013847. doi: 10.1002/14651858.CD013847.pub2. PMID: 36688481Free PMC Article
Cannabidiol in canine epilepsy.
Potschka H, Bhatti SFM, Tipold A, McGrath S
Vet J 2022 Dec;290:105913. Epub 2022 Oct 6 doi: 10.1016/j.tvjl.2022.105913. PMID: 36209995
Diffuse Low-Grade Glioma-Related Epilepsy.
Pallud J, McKhann GM
Neurosurg Clin N Am 2019 Jan;30(1):43-54. Epub 2018 Nov 1 doi: 10.1016/j.nec.2018.09.001. PMID: 30470404
Autoantibody-Mediated Encephalitis.
Wandinger KP, Leypoldt F, Junker R
Dtsch Arztebl Int 2018 Nov 5;115(40):666-673. doi: 10.3238/arztebl.2018.0666. PMID: 30381132Free PMC Article
Epilepsy.
Fauser S, Tumani H
Handb Clin Neurol 2017;146:259-266. doi: 10.1016/B978-0-12-804279-3.00015-0. PMID: 29110774

Recent systematic reviews

Prognosis of adults and children following a first unprovoked seizure.
Neligan A, Adan G, Nevitt SJ, Pullen A, Sander JW, Bonnett L, Marson AG
Cochrane Database Syst Rev 2023 Jan 23;1(1):CD013847. doi: 10.1002/14651858.CD013847.pub2. PMID: 36688481Free PMC Article
EEG-Based Epileptic Seizure Detection via Machine/Deep Learning Approaches: A Systematic Review.
Ahmad I, Wang X, Zhu M, Wang C, Pi Y, Khan JA, Khan S, Samuel OW, Chen S, Li G
Comput Intell Neurosci 2022;2022:6486570. Epub 2022 Jun 17 doi: 10.1155/2022/6486570. PMID: 35755757Free PMC Article
Epilepsy and syphilis: A systematic review and meta-analysis.
Zhang C, Yue W, Hou S, Cui W, Xiang L
Indian J Dermatol Venereol Leprol 2021 [SEASON];87(4):483-490. doi: 10.25259/IJDVL_681_19. PMID: 34219436
Treatment of infantile spasms.
Hancock EC, Osborne JP, Edwards SW
Cochrane Database Syst Rev 2013 Jun 5;2013(6):CD001770. doi: 10.1002/14651858.CD001770.pub3. PMID: 23740534Free PMC Article
Treatment of infantile spasms.
Hancock EC, Osborne JP, Edwards SW
Cochrane Database Syst Rev 2008 Oct 8;(4):CD001770. doi: 10.1002/14651858.CD001770.pub2. PMID: 18843624

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