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Velopharyngeal dysfunction

MedGen UID:
903100
•Concept ID:
C4280669
•
Disease or Syndrome
Synonyms: Incomplete closure of velopharyngeal apparatus; Velopharyngeal inadequacy
SNOMED CT: Velopharyngeal inadequacy (229727006); Incomplete closure of velopharyngeal apparatus (229727006); Velopharyngeal dysfunction (229727006)

Definition

Failure of velopharyngeal valve to seal completely due to structural or neurologic abnormality or velopharyngeal mislearning. [from SNOMEDCT_US]

Professional guidelines

PubMed

Velopharyngeal Dysfunction Evaluation and Treatment.
Meier JD, Muntz HR
Facial Plast Surg Clin North Am 2016 Nov;24(4):477-485. doi: 10.1016/j.fsc.2016.06.016. PMID: 27712815
Diagnosis and Management of Velopharyngeal Dysfunction.
Glade RS, Deal R
Oral Maxillofac Surg Clin North Am 2016 May;28(2):181-8. doi: 10.1016/j.coms.2015.12.004. PMID: 27150305
Non-cleft causes of velopharyngeal dysfunction: implications for treatment.
Kummer AW, Marshall JL, Wilson MM
Int J Pediatr Otorhinolaryngol 2015 Mar;79(3):286-95. Epub 2015 Jan 5 doi: 10.1016/j.ijporl.2014.12.036. PMID: 25604261

Recent clinical studies

Etiology

Evidence-Based Practices in Cleft Palate Surgery.
Applebaum SA, Aronson S, Termanini KM, Gosain AK
Plast Reconstr Surg 2024 Feb 1;153(2):448e-461e. Epub 2024 Jan 24 doi: 10.1097/PRS.0000000000011035. PMID: 38266141
Surgical Management of Velopharyngeal Dysfunction.
Arganbright J
Facial Plast Surg Clin North Am 2024 Feb;32(1):69-83. Epub 2023 Aug 9 doi: 10.1016/j.fsc.2023.06.007. PMID: 37981418
Cleft Lip and Palate.
Worley ML, Patel KG, Kilpatrick LA
Clin Perinatol 2018 Dec;45(4):661-678. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.006. PMID: 30396411
What's New in Cleft Palate and Velopharyngeal Dysfunction Management?
Naran S, Ford M, Losee JE
Plast Reconstr Surg 2017 Jun;139(6):1343e-1355e. doi: 10.1097/PRS.0000000000003335. PMID: 28538580
Types and causes of velopharyngeal dysfunction.
Kummer AW
Semin Speech Lang 2011 May;32(2):150-8. Epub 2011 Sep 26 doi: 10.1055/s-0031-1277717. PMID: 21948641

Diagnosis

Management of submucous cleft palate.
Dean KM, Leeper LK
Curr Opin Otolaryngol Head Neck Surg 2020 Dec;28(6):410-413. doi: 10.1097/MOO.0000000000000673. PMID: 33105231
Cleft Lip and Palate.
Worley ML, Patel KG, Kilpatrick LA
Clin Perinatol 2018 Dec;45(4):661-678. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.006. PMID: 30396411
Velopharyngeal Dysfunction Evaluation and Treatment.
Meier JD, Muntz HR
Facial Plast Surg Clin North Am 2016 Nov;24(4):477-485. doi: 10.1016/j.fsc.2016.06.016. PMID: 27712815
Diagnosis and Management of Velopharyngeal Dysfunction.
Glade RS, Deal R
Oral Maxillofac Surg Clin North Am 2016 May;28(2):181-8. doi: 10.1016/j.coms.2015.12.004. PMID: 27150305
Surgical speech disorders.
Shen T, Sie KC
Facial Plast Surg Clin North Am 2014 Nov;22(4):593-609. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.010. PMID: 25444731

Therapy

Sphincter Pharyngoplasty for Velopharyngeal Dysfunction: Impact of 22q11.2 Deletion Syndrome.
Pattisapu P, Kinter S, Bly RA, Dahl JP, Perkins JA, Wang X, Sie KCY
Laryngoscope 2023 Oct;133(10):2813-2820. Epub 2023 Jan 25 doi: 10.1002/lary.30579. PMID: 36695155
Velopharyngeal dysfunction from intranasal substance abuse: Case series and review of literature.
You P, Chow L, Dworschak-Stokan A, Husein M
Laryngoscope 2018 Dec;128(12):2721-2725. Epub 2018 May 14 doi: 10.1002/lary.27240. PMID: 29756302
A Review of Randomized Controlled Trials in Cleft and Craniofacial Surgery.
Bekisz JM, Fryml E, Flores RL
J Craniofac Surg 2018 Mar;29(2):293-301. doi: 10.1097/SCS.0000000000004100. PMID: 29084117
Update on surgery for velopharyngeal dysfunction.
Crockett DJ, Goudy SL
Curr Opin Otolaryngol Head Neck Surg 2014 Aug;22(4):267-75. doi: 10.1097/MOO.0000000000000063. PMID: 24874210
The evaluation and management of velopharyngeal dysfunction.
Marsh JL
Clin Plast Surg 2004 Apr;31(2):261-9. doi: 10.1016/S0094-1298(03)00124-X. PMID: 15145668

Prognosis

Furlow Palatoplasty for Velopharyngeal Dysfunction Management: Auditing and Predicting Outcomes.
Bonanthaya K, Jalil J, Sasikumar AV, Shetty PN
Cleft Palate Craniofac J 2022 Sep;59(9):1097-1106. Epub 2021 Aug 17 doi: 10.1177/10556656211035914. PMID: 34402312
Risk factors for velopharyngeal dysfunction following orthognathic surgery in the cleft population.
Vella JB, Tatum SA
Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):317-323. doi: 10.1097/MOO.0000000000000553. PMID: 31274569
Cleft Lip and Palate.
Worley ML, Patel KG, Kilpatrick LA
Clin Perinatol 2018 Dec;45(4):661-678. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.006. PMID: 30396411
What's New in Cleft Palate and Velopharyngeal Dysfunction Management?
Naran S, Ford M, Losee JE
Plast Reconstr Surg 2017 Jun;139(6):1343e-1355e. doi: 10.1097/PRS.0000000000003335. PMID: 28538580
Types and causes of velopharyngeal dysfunction.
Kummer AW
Semin Speech Lang 2011 May;32(2):150-8. Epub 2011 Sep 26 doi: 10.1055/s-0031-1277717. PMID: 21948641

Clinical prediction guides

Comprehensive evaluation of velopharyngeal function in myasthenia gravis patients.
Dumbak AB, Kayıkcı MEK, Şahin Mİ, Kuşçu O, Bekircan-Kurt CE, Özdamar SE
Acta Neurol Belg 2022 Oct;122(5):1229-1236. Epub 2022 Mar 20 doi: 10.1007/s13760-022-01904-5. PMID: 35306634
Surgical interventions in velopharyngeal dysfunction: comparative perceptual speech and nasometric outcomes for three techniques.
Instrum R, Dzioba A, Dworschak-Stokan A, Husein M
J Otolaryngol Head Neck Surg 2022 Feb 4;51(1):3. doi: 10.1186/s40463-021-00548-4. PMID: 35120565Free PMC Article
Furlow Palatoplasty for Velopharyngeal Dysfunction Management: Auditing and Predicting Outcomes.
Bonanthaya K, Jalil J, Sasikumar AV, Shetty PN
Cleft Palate Craniofac J 2022 Sep;59(9):1097-1106. Epub 2021 Aug 17 doi: 10.1177/10556656211035914. PMID: 34402312
Risk factors for velopharyngeal dysfunction following orthognathic surgery in the cleft population.
Vella JB, Tatum SA
Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):317-323. doi: 10.1097/MOO.0000000000000553. PMID: 31274569
Acquired Velopharyngeal Dysfunction: Survey, Literature Review, and Clinical Recommendations.
Guyton KB, Sandage MJ, Bailey D, Haak N, Molt L, Plumb A
Am J Speech Lang Pathol 2018 Nov 21;27(4):1572-1597. doi: 10.1044/2018_AJSLP-17-0222. PMID: 30208483

Recent systematic reviews

Treatment algorithm for velopharyngeal dysfunction in patients with cleft palate: a systematic review.
Asar A, Gaber R, Yehia M, El-Kassaby MAW
Br J Oral Maxillofac Surg 2023 May;61(4):259-266. Epub 2023 Mar 11 doi: 10.1016/j.bjoms.2023.03.002. PMID: 37117086
Acquired Velopharyngeal Dysfunction: Survey, Literature Review, and Clinical Recommendations.
Guyton KB, Sandage MJ, Bailey D, Haak N, Molt L, Plumb A
Am J Speech Lang Pathol 2018 Nov 21;27(4):1572-1597. doi: 10.1044/2018_AJSLP-17-0222. PMID: 30208483
Surgery for Velopharyngeal Dysfunction: A Systematic Review of Interventions and Outcomes.
de Blacam C, Smith S, Orr D
Cleft Palate Craniofac J 2018 Mar;55(3):405-422. Epub 2017 Dec 14 doi: 10.1177/1055665617735102. PMID: 29437504
A Review of Randomized Controlled Trials in Cleft and Craniofacial Surgery.
Bekisz JM, Fryml E, Flores RL
J Craniofac Surg 2018 Mar;29(2):293-301. doi: 10.1097/SCS.0000000000004100. PMID: 29084117
Effectiveness of nasopharyngoscopic biofeedback in clients with cleft palate speech: a systematic review.
Neumann S, Romonath R
Logoped Phoniatr Vocol 2012 Oct;37(3):95-106. Epub 2011 Dec 7 doi: 10.3109/14015439.2011.638669. PMID: 22145632

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