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Solitary rectal ulcer syndrome

MedGen UID:
906337
•Concept ID:
C4274343
•
Disease or Syndrome
Synonyms: solitary rectal ulcer syndrome; Solitary ulcer syndrome
SNOMED CT: Solitary rectal ulcer syndrome (716685003); Solitary ulcer syndrome (716685003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0016208
Orphanet: ORPHA209964

Definition

A rare rectal disease characterised by rectal bleeding, abdominal pain, passage of mucous, sensation of incomplete evacuation, straining at defaecation and rectal prolapse, secondary to ischaemic changes in the rectum. [from SNOMEDCT_US]

Professional guidelines

PubMed

Rectal Prolapse in Children: Significance and Management.
Cares K, El-Baba M
Curr Gastroenterol Rep 2016 May;18(5):22. doi: 10.1007/s11894-016-0496-y. PMID: 27086003
ANMS-ESNM position paper and consensus guidelines on biofeedback therapy for anorectal disorders.
Rao SS, Benninga MA, Bharucha AE, Chiarioni G, Di Lorenzo C, Whitehead WE
Neurogastroenterol Motil 2015 May;27(5):594-609. Epub 2015 Apr 1 doi: 10.1111/nmo.12520. PMID: 25828100Free PMC Article
Solitary rectal ulcer syndrome: clinical features, pathophysiology, diagnosis and treatment strategies.
Zhu QC, Shen RR, Qin HL, Wang Y
World J Gastroenterol 2014 Jan 21;20(3):738-44. doi: 10.3748/wjg.v20.i3.738. PMID: 24574747Free PMC Article

Recent clinical studies

Etiology

Solitary rectal ulcer syndrome in 102 patients: Do different phenotypes make sense?
Gouriou C, Siproudhis L, Chambaz M, Ropert A, Wallenhorst T, Merlini-l'Héritier A, Carlo A, Bouguen G, Brochard C
Dig Liver Dis 2021 Feb;53(2):190-195. Epub 2020 Nov 13 doi: 10.1016/j.dld.2020.10.041. PMID: 33199231
Fecal evacuation disorders in anal fissure, hemorrhoids, and solitary rectal ulcer syndrome.
Jain M, Baijal R, Srinivas M, Venkataraman J
Indian J Gastroenterol 2019 Apr;38(2):173-177. Epub 2019 Feb 1 doi: 10.1007/s12664-018-0927-9. PMID: 30707420
Solitary Rectal Ulcer Syndrome in Children: A Case Series Study.
Kowalska-Duplaga K, Lazowska-Przeorek I, Karolewska-Bochenek K, Woynarowski M, Czaja-Bulsa G, Stawarski A, Pieczarkowski S, Hapyn E, Jozefczuk J, Korczowski B, Szaflarska-Poplawska A, Banaszkiewicz A
Adv Exp Med Biol 2017;1020:105-112. doi: 10.1007/5584_2017_2. PMID: 28255911
Solitary rectal ulcer syndrome: A single-center case series.
AlGhulayqah AI, Abu-Farhaneh EH, AlSohaibani FI, Almadi MA, AlMana HM
Saudi J Gastroenterol 2016 Nov;22(6):456-460. doi: 10.4103/1319-3767.195555. PMID: 27976642Free PMC Article
Solitary rectal ulcer syndrome: an endoscopic and histological presentation and literature review.
Chiang JM, Changchien CR, Chen JR
Int J Colorectal Dis 2006 May;21(4):348-56. Epub 2005 Aug 17 doi: 10.1007/s00384-005-0020-6. PMID: 16133006

Diagnosis

Solitary rectal ulcer syndrome.
Felt-Bersma RJF
Curr Opin Gastroenterol 2021 Jan;37(1):59-65. doi: 10.1097/MOG.0000000000000689. PMID: 33060396
Anorectal Disorders: An Update.
Rao SSC, Tetangco EP
J Clin Gastroenterol 2020 Aug;54(7):606-613. doi: 10.1097/MCG.0000000000001348. PMID: 32692116
Solitary rectal ulcer syndrome: A systematic review.
Forootan M, Darvishi M
Medicine (Baltimore) 2018 May;97(18):e0565. doi: 10.1097/MD.0000000000010565. PMID: 29718850Free PMC Article
Lower Gastrointestinal Bleeding in Children.
Sahn B, Bitton S
Gastrointest Endosc Clin N Am 2016 Jan;26(1):75-98. doi: 10.1016/j.giec.2015.08.007. PMID: 26616898
Solitary rectal ulcer syndrome: clinical features, pathophysiology, diagnosis and treatment strategies.
Zhu QC, Shen RR, Qin HL, Wang Y
World J Gastroenterol 2014 Jan 21;20(3):738-44. doi: 10.3748/wjg.v20.i3.738. PMID: 24574747Free PMC Article

Therapy

Solitary Rectal Ulcer Syndrome: A Rare and Often Misdiagnosed Cause of Rectal Bleeding in Children.
Nahid K, Sayeed M, Rukunuzzaman M, Saha BK
Mymensingh Med J 2022 Oct;31(4):1206-1211. PMID: 36189574
Management of solitary rectal ulcer syndome: Results of a french national survey: Société Nationale Française de Coloproctologie SNFCP, France.
Gouriou C, Chambaz M, Ropert A, Bouguen G, Venara A, Meurette G, Siproudhis L, Brochard C
Dig Liver Dis 2020 Aug;52(8):885-888. Epub 2020 Jun 10 doi: 10.1016/j.dld.2020.05.013. PMID: 32532605
Solitary Rectal Ulcer Syndrome: Demographic, Clinical, Endoscopic and Histological Panorama.
Abbasi A, Bhutto AR, Taj A, Aurangzaib, Baloch A, Masroor M, Munir SM
J Coll Physicians Surg Pak 2015 Dec;25(12):867-9. PMID: 26691359
Medical and surgical management of pelvic floor disorders affecting defecation.
Schey R, Cromwell J, Rao SS
Am J Gastroenterol 2012 Nov;107(11):1624-33; quiz p.1634. Epub 2012 Aug 21 doi: 10.1038/ajg.2012.247. PMID: 22907620Free PMC Article
Laparoscopic rectopexy in solitary rectal ulcer.
Kargar S, Salmanroughani H, Binesh F, Taghipoor S, Kargar S
Acta Med Iran 2011;49(12):810-3. PMID: 22174170

Prognosis

Clinical presentation of and outcome for solitary rectal ulcer syndrome in children.
Blackburn C, McDermott M, Bourke B
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):263-5. doi: 10.1097/MPG.0b013e31823014c0. PMID: 22266488
Solitary rectal ulcer syndrome in children and adolescents.
Perito ER, Mileti E, Dalal DH, Cho SJ, Ferrell LD, McCracken M, Heyman MB
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):266-70. doi: 10.1097/MPG.0b013e318240bba5. PMID: 22094902Free PMC Article
Solitary rectal ulcer syndrome: a clinicopathological study of 13 cases.
Al-Brahim N, Al-Awadhi N, Al-Enezi S, Alsurayei S, Ahmad M
Saudi J Gastroenterol 2009 Jul-Sep;15(3):188-92. doi: 10.4103/1319-3767.54749. PMID: 19636181Free PMC Article
Isolated colonic ulcers: diagnosis and management.
Nagar AB
Curr Gastroenterol Rep 2007 Oct;9(5):422-8. doi: 10.1007/s11894-007-0053-9. PMID: 17991345
Solitary rectal ulcer syndrome: a series of 13 patients operated with a mean follow-up of 4.5 years.
Marchal F, Bresler L, Brunaud L, Adler SC, Sebbag H, Tortuyaux JM, Boissel P
Int J Colorectal Dis 2001 Aug;16(4):228-33. doi: 10.1007/s003840100303. PMID: 11515682

Clinical prediction guides

Long-term results of sacral neuromodulation for the treatment of anorectal diseases.
Duchalais E, Drissi F, Delestre M, Wyart V, Lehur PA, Meurette G
J Visc Surg 2022 Dec;159(6):463-470. Epub 2021 Nov 1 doi: 10.1016/j.jviscsurg.2021.09.007. PMID: 34736877
Solitary rectal ulcer syndrome (SRUS): observational case series findings on MR defecography.
Abdelatty MA, Halligan S, El Sayed RF, Plumb AAO
Eur Radiol 2021 Nov;31(11):8597-8605. Epub 2021 Aug 6 doi: 10.1007/s00330-021-08075-6. PMID: 34357449
Solitary rectal ulcer syndrome in 102 patients: Do different phenotypes make sense?
Gouriou C, Siproudhis L, Chambaz M, Ropert A, Wallenhorst T, Merlini-l'Héritier A, Carlo A, Bouguen G, Brochard C
Dig Liver Dis 2021 Feb;53(2):190-195. Epub 2020 Nov 13 doi: 10.1016/j.dld.2020.10.041. PMID: 33199231
Solitary Rectal Ulcer Syndrome: Demographic, Clinical, Endoscopic and Histological Panorama.
Abbasi A, Bhutto AR, Taj A, Aurangzaib, Baloch A, Masroor M, Munir SM
J Coll Physicians Surg Pak 2015 Dec;25(12):867-9. PMID: 26691359
Solitary rectal ulcer syndrome: a case series.
Suresh N, Ganesh R, Sathiyasekaran M
Indian Pediatr 2010 Dec;47(12):1059-61. Epub 2010 Mar 15 doi: 10.1007/s13312-010-0177-0. PMID: 20453265

Recent systematic reviews

Efficacy of surgical treatments for the management of solitary rectal ulcer syndrome: a network meta-analysis.
Gaj F, Lai Q, Gelormini E, Ceci M, Di Saverio S, Quaresima S
Colorectal Dis 2024 Aug;26(8):1515-1534. Epub 2024 Jul 3 doi: 10.1111/codi.17080. PMID: 38957108
A systematic review and meta-analysis of the efficacy of medical treatments for the management of solitary rectal ulcer syndrome.
Qari Y, Mosli M
Saudi J Gastroenterol 2020 Jan-Feb;26(1):4-12. doi: 10.4103/sjg.SJG_213_19. PMID: 31898642Free PMC Article
A systematic literature review on solitary rectal ulcer syndrome: is there a therapeutic consensus in 2018?
Gouriou C, Chambaz M, Ropert A, Bouguen G, Desfourneaux V, Siproudhis L, Brochard C
Int J Colorectal Dis 2018 Dec;33(12):1647-1655. Epub 2018 Sep 11 doi: 10.1007/s00384-018-3162-z. PMID: 30206681
Solitary rectal ulcer syndrome: A systematic review.
Forootan M, Darvishi M
Medicine (Baltimore) 2018 May;97(18):e0565. doi: 10.1097/MD.0000000000010565. PMID: 29718850Free PMC Article
Surgery for constipation: systematic review and practice recommendations: Results II: Hitching procedures for the rectum (rectal suspension).
Grossi U, Knowles CH, Mason J, Lacy-Colson J, Brown SR; NIHR CapaCiTY working group; Pelvic floor Society
Colorectal Dis 2017 Sep;19 Suppl 3:37-48. doi: 10.1111/codi.13773. PMID: 28960927

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