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Immunoglobulin G4 related disease

MedGen UID:
923914
Concept ID:
C4087124
Disease or Syndrome
Synonyms: Autoimmune Disease, IgG4-Associated; IgG4 Associated Autoimmune Disease; IgG4 Related Disease; IgG4 Related Systemic Disease; IgG4-Associated Autoimmune Disease; IgG4-Associated Autoimmune Diseases; IgG4-RD; IgG4-Related Disease; IgG4-Related Diseases; Immunoglobulin G4 Related Disease; Immunoglobulin G4-Related Disease; Immunoglobulin G4-Related Diseases
SNOMED CT: IgG4 related disease (10743271000119103); Immunoglobulin G4 related disease (10743271000119103); Immunoglobulin G4 related systemic disease (10743271000119103)

Definition

A clinical disease characterized by elevated serum IgG4 concentration and tumefaction or tissue infiltration by IgG4-positive plasma cells. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmunoglobulin G4 related disease

Professional guidelines

PubMed

Varghese JL, Fung AWS, Mattman A, Quach TTT, Gauiran DTV, Carruthers MN, Chen LYC
Clin Chim Acta 2020 Jul;506:228-235. Epub 2020 Apr 6 doi: 10.1016/j.cca.2020.04.001. PMID: 32272158
Tanaka T, Masumori N
Int J Urol 2020 May;27(5):387-394. Epub 2020 Mar 12 doi: 10.1111/iju.14218. PMID: 32166828
Keser G, Aksu K
Rheumatol Int 2019 Feb;39(2):169-185. Epub 2018 Sep 17 doi: 10.1007/s00296-018-4157-3. PMID: 30221327

Recent clinical studies

Etiology

Orozco-Gálvez O, Fernández-Codina A, Lanzillotta M, Ebbo M, Schleinitz N, Culver EL, Rebours V, D'Cruz DP, Della-Torre E, Martínez-Valle F
Autoimmun Rev 2023 Mar;22(3):103273. Epub 2023 Jan 20 doi: 10.1016/j.autrev.2023.103273. PMID: 36682575
Perugino CA, Stone JH
Nat Rev Rheumatol 2020 Dec;16(12):702-714. Epub 2020 Sep 16 doi: 10.1038/s41584-020-0500-7. PMID: 32939060
Löhr JM, Beuers U, Vujasinovic M, Alvaro D, Frøkjær JB, Buttgereit F, Capurso G, Culver EL, de-Madaria E, Della-Torre E, Detlefsen S, Dominguez-Muñoz E, Czubkowski P, Ewald N, Frulloni L, Gubergrits N, Duman DG, Hackert T, Iglesias-Garcia J, Kartalis N, Laghi A, Lammert F, Lindgren F, Okhlobystin A, Oracz G, Parniczky A, Mucelli RMP, Rebours V, Rosendahl J, Schleinitz N, Schneider A, van Bommel EF, Verbeke CS, Vullierme MP, Witt H; UEG guideline working group
United European Gastroenterol J 2020 Jul;8(6):637-666. Epub 2020 Jun 18 doi: 10.1177/2050640620934911. PMID: 32552502Free PMC Article
Wallace ZS, Naden RP, Chari S, Choi HK, Della-Torre E, Dicaire JF, Hart PA, Inoue D, Kawano M, Khosroshahi A, Lanzillotta M, Okazaki K, Perugino CA, Sharma A, Saeki T, Schleinitz N, Takahashi N, Umehara H, Zen Y, Stone JH; Members of the ACR/EULAR IgG4-RD Classification Criteria Working Group
Ann Rheum Dis 2020 Jan;79(1):77-87. Epub 2019 Dec 3 doi: 10.1136/annrheumdis-2019-216561. PMID: 31796497
Wallace ZS, Naden RP, Chari S, Choi H, Della-Torre E, Dicaire JF, Hart PA, Inoue D, Kawano M, Khosroshahi A, Kubota K, Lanzillotta M, Okazaki K, Perugino CA, Sharma A, Saeki T, Sekiguchi H, Schleinitz N, Stone JR, Takahashi N, Umehara H, Webster G, Zen Y, Stone JH; American College of Rheumatology/European League Against Rheumatism IgG4-Related Disease Classification Criteria Working Group
Arthritis Rheumatol 2020 Jan;72(1):7-19. Epub 2019 Dec 2 doi: 10.1002/art.41120. PMID: 31793250

Diagnosis

Katz G, Stone JH
Annu Rev Med 2022 Jan 27;73:545-562. Epub 2021 Oct 20 doi: 10.1146/annurev-med-050219-034449. PMID: 34669430
Perugino CA, Stone JH
Nat Rev Rheumatol 2020 Dec;16(12):702-714. Epub 2020 Sep 16 doi: 10.1038/s41584-020-0500-7. PMID: 32939060
Wallace ZS, Naden RP, Chari S, Choi H, Della-Torre E, Dicaire JF, Hart PA, Inoue D, Kawano M, Khosroshahi A, Kubota K, Lanzillotta M, Okazaki K, Perugino CA, Sharma A, Saeki T, Sekiguchi H, Schleinitz N, Stone JR, Takahashi N, Umehara H, Webster G, Zen Y, Stone JH; American College of Rheumatology/European League Against Rheumatism IgG4-Related Disease Classification Criteria Working Group
Arthritis Rheumatol 2020 Jan;72(1):7-19. Epub 2019 Dec 2 doi: 10.1002/art.41120. PMID: 31793250
Sánchez-Oro R, Alonso-Muñoz EM, Martí Romero L
Gastroenterol Hepatol 2019 Dec;42(10):638-647. Epub 2019 Nov 11 doi: 10.1016/j.gastrohep.2019.08.009. PMID: 31722794
Morales AT, Cignarella AG, Jabeen IS, Barkin JS, Mirsaeidi M
Eur J Intern Med 2019 Aug;66:18-24. Epub 2019 Jun 19 doi: 10.1016/j.ejim.2019.06.010. PMID: 31227290

Therapy

Peyronel F, Fenaroli P, Maritati F, Schleinitz N, Vaglio A
Expert Rev Clin Immunol 2023 May;19(5):537-547. Epub 2023 Apr 6 doi: 10.1080/1744666X.2023.2195627. PMID: 36960748
Katz G, Stone JH
Annu Rev Med 2022 Jan 27;73:545-562. Epub 2021 Oct 20 doi: 10.1146/annurev-med-050219-034449. PMID: 34669430
Karadeniz H, Vaglio A
Turk J Med Sci 2020 Nov 3;50(SI-2):1616-1631. doi: 10.3906/sag-2006-375. PMID: 32777900Free PMC Article
Lanzillotta M, Mancuso G, Della-Torre E
BMJ 2020 Jun 16;369:m1067. doi: 10.1136/bmj.m1067. PMID: 32546500
Morales AT, Cignarella AG, Jabeen IS, Barkin JS, Mirsaeidi M
Eur J Intern Med 2019 Aug;66:18-24. Epub 2019 Jun 19 doi: 10.1016/j.ejim.2019.06.010. PMID: 31227290

Prognosis

Karadeniz H, Vaglio A
Turk J Med Sci 2020 Nov 3;50(SI-2):1616-1631. doi: 10.3906/sag-2006-375. PMID: 32777900Free PMC Article
Lanzillotta M, Mancuso G, Della-Torre E
BMJ 2020 Jun 16;369:m1067. doi: 10.1136/bmj.m1067. PMID: 32546500
Morales AT, Cignarella AG, Jabeen IS, Barkin JS, Mirsaeidi M
Eur J Intern Med 2019 Aug;66:18-24. Epub 2019 Jun 19 doi: 10.1016/j.ejim.2019.06.010. PMID: 31227290
Okamoto A, Watanabe T, Kamata K, Minaga K, Kudo M
Intern Med 2019 Jun 1;58(11):1533-1539. Epub 2019 Feb 1 doi: 10.2169/internalmedicine.2210-18. PMID: 30713326Free PMC Article
Chen LYC, Mattman A, Seidman MA, Carruthers MN
Haematologica 2019 Mar;104(3):444-455. Epub 2019 Jan 31 doi: 10.3324/haematol.2018.205526. PMID: 30705099Free PMC Article

Clinical prediction guides

Perugino CA, Wallace ZS, Zack DJ, Quinn SM, Poma A, Fernandes AD, Foster P, DeMattos S, Burington B, Liu H, Allard-Chamard H, Smith N, Kai X, Xing K, Pillai S, Stone JH
Lancet Rheumatol 2023 Aug;5(8):e442-e450. Epub 2023 Jul 24 doi: 10.1016/S2665-9913(23)00157-1. PMID: 38251576
Lu C, Li S, Qing P, Zhang Q, Ji X, Tang Z, Chen C, Wu T, Hu Y, Zhao Y, Zhang X, He Q, Fox DA, Tan C, Luo Y, Liu Y
JCI Insight 2023 Sep 8;8(17) doi: 10.1172/jci.insight.167602. PMID: 37561593Free PMC Article
Chaba A, Devresse A, Audard V, Boffa JJ, Karras A, Cartery C, Deltombe C, Chemouny J, Contamin C, Courivaud C, Duquennoy S, Garcia H, Joly D, Goumri N, Hanouna G, Halimi JM, Plaisier E, Hamidou M, Landron C, Launay D, Lebas C, Legendre M, Masseau A, Mathian A, Mercadal L, Morel N, Mutinelli-Szymanski P, Palat S, Pennaforte JL, Peraldi MN, Pozdzik A, Schleinitz N, Thaunat O, Titeca-Beauport D, Mussini C, Touati S, Prinz E, Faller AL, Richter S, Vilaine E, Ferlicot S, Von-Kotze C, Belliere J, Olagne J, Mesbah R, Snanoudj R, Nouvier M, Ebbo M, Zaidan M
Clin J Am Soc Nephrol 2023 Aug 1;18(8):1031-1040. Epub 2023 Jun 7 doi: 10.2215/CJN.0000000000000193. PMID: 37283461Free PMC Article
Lanzillotta M, Mancuso G, Della-Torre E
BMJ 2020 Jun 16;369:m1067. doi: 10.1136/bmj.m1067. PMID: 32546500
Kubo K, Yamamoto K
Int J Rheum Dis 2016 Aug;19(8):747-62. Epub 2015 Aug 10 doi: 10.1111/1756-185X.12586. PMID: 26259069

Recent systematic reviews

Dragos C, Joseph C, Elwell H, Dey M, Kouranloo K
Rheumatol Int 2024 Oct;44(10):1875-1886. Epub 2024 May 20 doi: 10.1007/s00296-024-05611-7. PMID: 38769126Free PMC Article
Sawada H, Czech T, Silangcruz K, Kozai L, Obeidat A, Wien EA, Nishimura MF, Nishikori A, Sato Y, Nishimura Y
J Gastroenterol Hepatol 2022 Oct;37(10):1865-1872. Epub 2022 Aug 21 doi: 10.1111/jgh.15980. PMID: 35949057
Katerji R, Smoller BR
Clin Dermatol 2021 Mar-Apr;39(2):283-290. Epub 2020 Oct 16 doi: 10.1016/j.clindermatol.2020.10.009. PMID: 34272023
Karim F, Loeffen J, Bramer W, Westenberg L, Verdijk R, van Hagen M, van Laar J
Pediatr Rheumatol Online J 2016 Mar 25;14(1):18. doi: 10.1186/s12969-016-0079-3. PMID: 27012661Free PMC Article
Mulholland GB, Jeffery CC, Satija P, Côté DW
J Otolaryngol Head Neck Surg 2015 Jun 20;44(1):24. doi: 10.1186/s40463-015-0071-9. PMID: 26092582Free PMC Article

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