U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anti-PIT-1 Antibody Syndrome

MedGen UID:
878913
•Concept ID:
C4046049
•
Disease or Syndrome
Synonyms: Anti PIT 1 Antibody Syndrome; Anti-PIT-1 Antibody Syndromes; Antibody Syndrome, Anti-PIT-1; Antibody Syndromes, Anti-PIT-1; Syndrome, Anti-PIT-1 Antibody; Syndromes, Anti-PIT-1 Antibody

Professional guidelines

PubMed

Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline.
Husebye ES, Castinetti F, Criseno S, Curigliano G, Decallonne B, Fleseriu M, Higham CE, Lupi I, Paschou SA, Toth M, van der Kooij M, Dekkers OM
Eur J Endocrinol 2022 Dec 1;187(6):G1-G21. Epub 2022 Oct 25 doi: 10.1530/EJE-22-0689. PMID: 36149449Free PMC Article
MECHANISMS IN ENDOCRINOLOGY: Hypophysitis: diagnosis and treatment.
Joshi MN, Whitelaw BC, Carroll PV
Eur J Endocrinol 2018 Sep;179(3):R151-R163. Epub 2018 Jun 7 doi: 10.1530/EJE-17-0009. PMID: 29880706
The management of hypophysitis.
Karaca Z, Kelestimur F
Minerva Endocrinol 2016 Sep;41(3):390-9. Epub 2016 Mar 10 PMID: 26963662

Recent clinical studies

Etiology

A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.
Yamamoto M, Iguchi G, Bando H, Fukuoka H, Suda K, Takahashi M, Nishizawa H, Matsumoto R, Tojo K, Mokubo A, Ogata T, Takahashi Y
Endocr J 2014;61(6):641-4. Epub 2014 Apr 20 doi: 10.1507/endocrj.ej13-0539. PMID: 24748456

Diagnosis

Review on Recent Topics in Hypophysitis.
Sugihara H
J Nippon Med Sch 2017;84(5):201-208. doi: 10.1272/jnms.84.201. PMID: 29142180
A novel thymoma-associated autoimmune disease: Anti-PIT-1 antibody syndrome.
Bando H, Iguchi G, Okimura Y, Odake Y, Yoshida K, Matsumoto R, Suda K, Nishizawa H, Fukuoka H, Mokubo A, Tojo K, Maniwa Y, Ogawa W, Takahashi Y
Sci Rep 2017 Feb 20;7:43060. doi: 10.1038/srep43060. PMID: 28216655Free PMC Article
Autoimmune hypophysitis: new developments.
Takahashi Y
Handb Clin Neurol 2014;124:417-22. doi: 10.1016/B978-0-444-59602-4.00029-0. PMID: 25248604

Therapy

Review on Recent Topics in Hypophysitis.
Sugihara H
J Nippon Med Sch 2017;84(5):201-208. doi: 10.1272/jnms.84.201. PMID: 29142180

Prognosis

Review on Recent Topics in Hypophysitis.
Sugihara H
J Nippon Med Sch 2017;84(5):201-208. doi: 10.1272/jnms.84.201. PMID: 29142180

Clinical prediction guides

Autoimmune Pituitary Disease: New Concepts With Clinical Implications.
Yamamoto M, Iguchi G, Bando H, Kanie K, Hidaka-Takeno R, Fukuoka H, Takahashi Y
Endocr Rev 2020 Apr 1;41(2) doi: 10.1210/endrev/bnz003. PMID: 31513261
Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome.
Bando H, Iguchi G, Fukuoka H, Yamamoto M, Hidaka-Takeno R, Okimura Y, Matsumoto R, Suda K, Nishizawa H, Takahashi M, Tojo K, Takahashi Y
J Clin Endocrinol Metab 2014 Sep;99(9):E1744-9. Epub 2014 Jun 17 doi: 10.1210/jc.2014-1769. PMID: 24937538
Adult combined GH, prolactin, and TSH deficiency associated with circulating PIT-1 antibody in humans.
Yamamoto M, Iguchi G, Takeno R, Okimura Y, Sano T, Takahashi M, Nishizawa H, Handayaningshi AE, Fukuoka H, Tobita M, Saitoh T, Tojo K, Mokubo A, Morinobu A, Iida K, Kaji H, Seino S, Chihara K, Takahashi Y
J Clin Invest 2011 Jan;121(1):113-9. Epub 2010 Dec 1 doi: 10.1172/JCI44073. PMID: 21123951Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...