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Penetrating foot ulcers

MedGen UID:
871321
•Concept ID:
C4025809
•
Disease or Syndrome
HPO: HP:0001026

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Penetrating foot ulcers

Professional guidelines

PubMed

MXenes-integrated microneedle combined with asiaticoside to penetrate the cuticle for treatment of diabetic foot ulcer.
Wang P, Wang Y, Yi Y, Gong Y, Ji H, Gan Y, Xie F, Fan J, Wang X
J Nanobiotechnology 2022 Jun 7;20(1):259. doi: 10.1186/s12951-022-01468-9. PMID: 35672708Free PMC Article
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Emerging issues in the diagnosis and management of infections caused by multi-drug-resistant, gram-positive cocci.
Napolitano LM
Surg Infect (Larchmt) 2005;6 Suppl 2:S-5-22. PMID: 23577494

Recent clinical studies

Etiology

Engraftment of bioengineered three-dimensional scaffold from human amniotic membrane-derived extracellular matrix accelerates ischemic diabetic wound healing.
Nasiry D, Khalatbary AR, Abdollahifar MA, Amini A, Bayat M, Noori A, Piryaei A
Arch Dermatol Res 2021 Sep;313(7):567-582. Epub 2020 Sep 17 doi: 10.1007/s00403-020-02137-3. PMID: 32940766
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Management of wounds with exposed bone structures using an artificial dermis and skin grafting technique.
Chen X, Chen H, Zhang G
J Plast Reconstr Aesthet Surg 2010 Jun;63(6):e512-8. Epub 2009 Dec 9 doi: 10.1016/j.bjps.2009.11.004. PMID: 20004631
Cat-transmitted cutaneous lymphatic sporothricosis.
Xavier MH, Teixeira Ade L, Pinto JM, Rodrigues KS, Vilar EG, Souza AC, Pereira GB
Dermatol Online J 2008 Jul 15;14(7):4. PMID: 18718188
Calcaneal fractures in diabetic patients.
Hedlund LJ, Maki DD, Griffiths HJ
J Diabetes Complications 1998 Mar-Apr;12(2):81-7. doi: 10.1016/s1056-8727(97)00052-4. PMID: 9559485

Diagnosis

Indian foot and ankle scenario.
Shah R
Foot Ankle Spec 2011 Dec;4(6):390-5. doi: 10.1177/1938640011428788. PMID: 22184742
Puncture wounds in the diabetic foot: importance of X-ray in diagnosis.
Naraynsingh V, Maharaj R, Dan D, Hariharan S
Int J Low Extrem Wounds 2011 Jun;10(2):98-100. doi: 10.1177/1534734611411572. PMID: 21693446
An anatomic study of the superficial peroneal nerve accessory artery and its perforators, and clinical application of superficial peroneal nerve accessory artery perforator flaps.
Kim JS, Son DG, Choi TH, Kim NG, Lee KS, Han KH, Kim JH, Lee SI, Kang D
Ann Plast Surg 2008 Jun;60(6):710-6. doi: 10.1097/SAP.0b013e3180cab77f. PMID: 18520212
Calcaneal fractures in diabetic patients.
Hedlund LJ, Maki DD, Griffiths HJ
J Diabetes Complications 1998 Mar-Apr;12(2):81-7. doi: 10.1016/s1056-8727(97)00052-4. PMID: 9559485
Mal perforans and spina bifida occulta.
Lockman DS, Jones TM, Abele DC, Obbens E
Arch Dermatol 1978 Mar;114(3):404-5. PMID: 24425

Therapy

Engraftment of bioengineered three-dimensional scaffold from human amniotic membrane-derived extracellular matrix accelerates ischemic diabetic wound healing.
Nasiry D, Khalatbary AR, Abdollahifar MA, Amini A, Bayat M, Noori A, Piryaei A
Arch Dermatol Res 2021 Sep;313(7):567-582. Epub 2020 Sep 17 doi: 10.1007/s00403-020-02137-3. PMID: 32940766
Antibiotic Tissue Penetration in Diabetic Foot Infections A Review of the Microdialysis Literature and Needs for Future Research.
Ray A, Malin D, Nicolau DP, Wiskirchen DE
J Am Podiatr Med Assoc 2015 Nov;105(6):520-31. doi: 10.7547/14-036.1. PMID: 26667505
Cat-transmitted cutaneous lymphatic sporothricosis.
Xavier MH, Teixeira Ade L, Pinto JM, Rodrigues KS, Vilar EG, Souza AC, Pereira GB
Dermatol Online J 2008 Jul 15;14(7):4. PMID: 18718188
The diabetic foot: the importance of biofilms and wound bed preparation.
Davis SC, Martinez L, Kirsner R
Curr Diab Rep 2006 Dec;6(6):439-45. doi: 10.1007/s11892-006-0076-x. PMID: 17118226
Topical phenytoin for wound healing.
Bhatia A, Prakash S
Dermatol Online J 2004 Jul 15;10(1):5. PMID: 15347487

Prognosis

Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
Monteagudo B, Cabanillas M, Iriarte P, Ramírez-Santos A, León-Muinos E, González-Vilas D, Suárez-Amor Ó
Acta Dermatovenerol Croat 2018 Apr;26(1):61-63. PMID: 29782303
Cat-transmitted cutaneous lymphatic sporothricosis.
Xavier MH, Teixeira Ade L, Pinto JM, Rodrigues KS, Vilar EG, Souza AC, Pereira GB
Dermatol Online J 2008 Jul 15;14(7):4. PMID: 18718188
Diabetic foot osteomyelitis.
Hartemann-Heurtier A, Senneville E
Diabetes Metab 2008 Apr;34(2):87-95. Epub 2008 Jan 31 doi: 10.1016/j.diabet.2007.09.005. PMID: 18242114
A unique case of Cryptococcus laurentii keratitis spread by a rigid gas permeable contact lens in a patient with onychomycosis.
Ritterband DC, Seedor JA, Shah MK, Waheed S, Schorr I
Cornea 1998 Jan;17(1):115-8. doi: 10.1097/00003226-199801000-00017. PMID: 9436889
Investigations on the pathogenesis of venous leg ulcers.
Partsch H
Acta Chir Scand Suppl 1988;544:25-9. PMID: 3051824

Clinical prediction guides

Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
Monteagudo B, Cabanillas M, Iriarte P, Ramírez-Santos A, León-Muinos E, González-Vilas D, Suárez-Amor Ó
Acta Dermatovenerol Croat 2018 Apr;26(1):61-63. PMID: 29782303
Risk factors for major amputation in hospitalised diabetic foot patients.
Namgoong S, Jung S, Han SK, Jeong SH, Dhong ES, Kim WK
Int Wound J 2016 Mar;13 Suppl 1(Suppl 1):13-9. Epub 2015 Oct 19 doi: 10.1111/iwj.12526. PMID: 26478562Free PMC Article
Pharmacokinetics and penetration of moxifloxacin into infected diabetic foot tissue in a large diabetic patient cohort.
Majcher-Peszynska J, Sass M, Schipper S, Czaika V, Gussmann A, Lobmann R, Mundkowski RG, Luebbert C, Kujath P, Ruf BR, Koch H, Schareck W, Klar E, Drewelow B; Moxifloxacin-DFI Study Group
Eur J Clin Pharmacol 2011 Feb;67(2):135-42. Epub 2010 Sep 25 doi: 10.1007/s00228-010-0903-5. PMID: 20871984
Pharmacokinetics and penetration of linezolid into inflamed soft tissue in diabetic foot infections.
Majcher-Peszynska J, Haase G, Sass M, Mundkowski R, Pietsch A, Klammt S, Schareck W, Drewelow B
Eur J Clin Pharmacol 2008 Nov;64(11):1093-100. Epub 2008 Jul 25 doi: 10.1007/s00228-008-0531-5. PMID: 18654767
Diabetic foot osteomyelitis.
Hartemann-Heurtier A, Senneville E
Diabetes Metab 2008 Apr;34(2):87-95. Epub 2008 Jan 31 doi: 10.1016/j.diabet.2007.09.005. PMID: 18242114

Recent systematic reviews

Diabetes: foot ulcers and amputations.
Hunt DL
BMJ Clin Evid 2011 Aug 26;2011 PMID: 21871137Free PMC Article
Diabetes: foot ulcers and amputations.
Hunt D
BMJ Clin Evid 2009 Jan 12;2009 PMID: 19445774Free PMC Article

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