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Abnormal primary molar morphology

MedGen UID:
870608
•Concept ID:
C4025059
•
Anatomical Abnormality
Synonyms: Abnormality of deciduous molar morphology; Abnormality of primary molar morphology; Abnormality of shape of baby molar; Abnormality of shape of primary molar
 
HPO: HP:0006344

Definition

An abnormality of morphology of primary molar. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal primary molar morphology

Professional guidelines

PubMed

Clinical Characteristics and Differential Diagnosis of Hypomineralised Second Primary Molars and Molar Incisor Hypomineralisation.
Elfrink MEC, Weerheijm K
Monogr Oral Sci 2024;32:35-42. Epub 2024 Jul 1 doi: 10.1159/000538853. PMID: 39321783
Joubert syndrome: Molecular basis and treatment.
Spahiu L, Behluli E, Grajçevci-Uka V, Liehr T, Temaj G
J Mother Child 2022 Mar 1;26(1):118-123. Epub 2023 Feb 22 doi: 10.34763/jmotherandchild.20222601.d-22-00034. PMID: 36803942Free PMC Article
Genotype-phenotype correlates in Joubert syndrome: A review.
Gana S, Serpieri V, Valente EM
Am J Med Genet C Semin Med Genet 2022 Mar;190(1):72-88. Epub 2022 Mar 3 doi: 10.1002/ajmg.c.31963. PMID: 35238134Free PMC Article

Recent clinical studies

Etiology

Genotype-phenotype correlates in Joubert syndrome: A review.
Gana S, Serpieri V, Valente EM
Am J Med Genet C Semin Med Genet 2022 Mar;190(1):72-88. Epub 2022 Mar 3 doi: 10.1002/ajmg.c.31963. PMID: 35238134Free PMC Article
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
On the Etiology of Molar-Incisor Hypomineralization.
Vieira AR, Kup E
Caries Res 2016;50(2):166-9. Epub 2016 Apr 26 doi: 10.1159/000445128. PMID: 27111773
Joubert syndrome and related disorders.
Valente EM, Dallapiccola B, Bertini E
Handb Clin Neurol 2013;113:1879-88. doi: 10.1016/B978-0-444-59565-2.00058-7. PMID: 23622411
Joubert Syndrome and related disorders.
Brancati F, Dallapiccola B, Valente EM
Orphanet J Rare Dis 2010 Jul 8;5:20. doi: 10.1186/1750-1172-5-20. PMID: 20615230Free PMC Article

Diagnosis

Joubert syndrome: Molecular basis and treatment.
Spahiu L, Behluli E, Grajçevci-Uka V, Liehr T, Temaj G
J Mother Child 2022 Mar 1;26(1):118-123. Epub 2023 Feb 22 doi: 10.34763/jmotherandchild.20222601.d-22-00034. PMID: 36803942Free PMC Article
Genotype-phenotype correlates in Joubert syndrome: A review.
Gana S, Serpieri V, Valente EM
Am J Med Genet C Semin Med Genet 2022 Mar;190(1):72-88. Epub 2022 Mar 3 doi: 10.1002/ajmg.c.31963. PMID: 35238134Free PMC Article
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Taurodontism.
Mohan RP, Verma S, Agarwal N, Singh U
BMJ Case Rep 2013 Apr 17;2013 doi: 10.1136/bcr-2012-008490. PMID: 23598931Free PMC Article
Otodental syndrome.
Bloch-Zupan A, Goodman JR
Orphanet J Rare Dis 2006 Mar 21;1:5. doi: 10.1186/1750-1172-1-5. PMID: 16722606Free PMC Article

Therapy

The prevalence and characteristics of and the association between MIH and HSPM in South-Western France.
Estivals J, Fahd C, Baillet J, Rouas P, Manton DJ, Garot E
Int J Paediatr Dent 2023 May;33(3):298-304. Epub 2022 Dec 27 doi: 10.1111/ipd.13040. PMID: 36511101
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review.
Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A
Clin Oral Investig 2020 Mar;24(3):1287-1297. Epub 2019 Jul 16 doi: 10.1007/s00784-019-03007-7. PMID: 31312969
Association between Molar Incisor Hypomineralization in Schoolchildren and Both Prenatal and Postnatal Factors: A Population-Based Study.
Tourino LF, Corrêa-Faria P, Ferreira RC, Bendo CB, Zarzar PM, Vale MP
PLoS One 2016;11(6):e0156332. Epub 2016 Jun 9 doi: 10.1371/journal.pone.0156332. PMID: 27280451Free PMC Article
Fluorosis of the primary dentition: what does it mean for permanent teeth?
Warren JJ, Kanellis MJ, Levy SM
J Am Dent Assoc 1999 Mar;130(3):347-56. doi: 10.14219/jada.archive.1999.0204. PMID: 10085657

Prognosis

Genotype-phenotype correlates in Joubert syndrome: A review.
Gana S, Serpieri V, Valente EM
Am J Med Genet C Semin Med Genet 2022 Mar;190(1):72-88. Epub 2022 Mar 3 doi: 10.1002/ajmg.c.31963. PMID: 35238134Free PMC Article
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review.
Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A
Clin Oral Investig 2020 Mar;24(3):1287-1297. Epub 2019 Jul 16 doi: 10.1007/s00784-019-03007-7. PMID: 31312969
Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.
Bergendal B, Norderyd J, Zhou X, Klar J, Dahl N
BMC Med Genet 2016 Nov 24;17(1):88. doi: 10.1186/s12881-016-0349-4. PMID: 27881089Free PMC Article
Joubert Syndrome and related disorders.
Brancati F, Dallapiccola B, Valente EM
Orphanet J Rare Dis 2010 Jul 8;5:20. doi: 10.1186/1750-1172-5-20. PMID: 20615230Free PMC Article
Clinical and molecular features of Joubert syndrome and related disorders.
Parisi MA
Am J Med Genet C Semin Med Genet 2009 Nov 15;151C(4):326-40. doi: 10.1002/ajmg.c.30229. PMID: 19876931Free PMC Article

Clinical prediction guides

Prenatal exposure to environmental toxins and comprehensive dental findings in a population cohort of children.
Winkler JR, Dixon BL, Singh I, Soto R, Qiu Y, Zhang Y, Porucznik CA, Stanford JB
BMC Oral Health 2024 Mar 11;24(1):326. doi: 10.1186/s12903-023-03786-2. PMID: 38468230Free PMC Article
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
A three-dimensional analysis of primary failure of eruption in humans and mice.
Tokavanich N, Gupta A, Nagata M, Takahashi A, Matsushita Y, Yatabe M, Ruellas A, Cevidanes L, Maki K, Yamaguchi T, Ono N, Ono W
Oral Dis 2020 Mar;26(2):391-400. Epub 2019 Dec 17 doi: 10.1111/odi.13249. PMID: 31802584Free PMC Article
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review.
Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A
Clin Oral Investig 2020 Mar;24(3):1287-1297. Epub 2019 Jul 16 doi: 10.1007/s00784-019-03007-7. PMID: 31312969
Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.
Bergendal B, Norderyd J, Zhou X, Klar J, Dahl N
BMC Med Genet 2016 Nov 24;17(1):88. doi: 10.1186/s12881-016-0349-4. PMID: 27881089Free PMC Article

Recent systematic reviews

Self-correction of the ectopic eruption of the maxillary first permanent molar and its predictive factors: A systematic review.
Bastos RTDRM, Dos Santos CCO, Bellini-Pereira SA, Normando D
Int J Paediatr Dent 2024 Jul;34(4):348-359. Epub 2023 Oct 24 doi: 10.1111/ipd.13131. PMID: 37876132
Molar-root incisor malformation - a systematic review of case reports and case series.
Jensen ED, Smart G, Poirier BF, Sethi S
BMC Oral Health 2023 Aug 18;23(1):576. doi: 10.1186/s12903-023-03275-6. PMID: 37596569Free PMC Article
The Association of Developmental Dental Defects and the Clinical Consequences in the Primary Dentition: A Systematic Review of Observational Studies.
Portella PD, Dias BC, Ferreira P, de Souza JF, Wambier L, Assunção LRDS
Pediatr Dent 2022 Sep 15;44(5):330-341. PMID: 36309777
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review.
Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A
Clin Oral Investig 2020 Mar;24(3):1287-1297. Epub 2019 Jul 16 doi: 10.1007/s00784-019-03007-7. PMID: 31312969

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