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Hypomature dental enamel

MedGen UID:
869122
Concept ID:
C4023540
Finding
Synonyms: Immature tooth enamel; Soft teeth; Soft tooth enamel
 
HPO: HP:0011085

Definition

A form of hypomineralization of enamel characterized by a chalky appearance of the enamel with orange, brown, or white color. [from HPO]

Term Hierarchy

Conditions with this feature

Amelogenesis imperfecta hypomaturation type 2A3
MedGen UID:
416381
Concept ID:
C2750771
Disease or Syndrome
Any amelogenesis imperfecta in which the cause of the disease is a mutation in the WDR72 gene.

Professional guidelines

PubMed

Wang SK, Zhang H, Lin HC, Wang YL, Lin SC, Seymen F, Koruyucu M, Simmer JP, Hu JC
Int J Mol Sci 2024 Jun 1;25(11) doi: 10.3390/ijms25116132. PMID: 38892321Free PMC Article
Möhlhenrich SC, Chhatwani S, Schmidt P, Kniha K, Postberg J, Schulte AG, Jackowski J, Zimmer S, Danesh G
Head Face Med 2024 Jun 14;20(1):36. doi: 10.1186/s13005-024-00436-y. PMID: 38877506Free PMC Article
Seow WK
Pediatr Dent 1993 Nov-Dec;15(6):384-93. PMID: 8152999

Recent clinical studies

Etiology

Wang YL, Lin HC, Liang T, Lin JC, Simmer JP, Hu JC, Wang SK
J Dent Res 2024 Jun;103(6):662-671. Epub 2024 May 8 doi: 10.1177/00220345241236695. PMID: 38716742Free PMC Article
Hany U, Watson CM, Liu L, Nikolopoulos G, Smith CEL, Poulter JA, Brown CJ, Patel A, Rodd HD, Balmer R, Harfoush A, Al-Jawad M, Inglehearn CF, Mighell AJ
J Dent Res 2024 Jan;103(1):22-30. Epub 2023 Dec 6 doi: 10.1177/00220345231203694. PMID: 38058155Free PMC Article
Adorno-Farias D, Ortega-Pinto A, Gajardo P, Salazar A, Morales-Bozo I, Werlinger F, Rojas-Flores S, Molina-Berríos A, Echeverría-López S, Jara-Sandoval J, Jara L, Urzúa B
J Appl Oral Sci 2019 Apr 1;27:e20180359. doi: 10.1590/1678-7757-2018-0359. PMID: 30970114Free PMC Article
Chiu YE, Siegel DH, Drolet BA, Hodgson BD
Pediatr Dermatol 2014 Jul-Aug;31(4):455-8. Epub 2014 Jun 11 doi: 10.1111/pde.12361. PMID: 24916277
Urzúa B, Ortega-Pinto A, Morales-Bozo I, Rojas-Alcayaga G, Cifuentes V
Biochem Genet 2011 Feb;49(1-2):104-21. Epub 2010 Dec 3 doi: 10.1007/s10528-010-9392-6. PMID: 21127961

Diagnosis

Zhang Z, Zou X, Feng L, Huang Y, Chen F, Sun K, Song Y, Lv P, Gao X, Dong Y, Tian H
BMC Oral Health 2023 Nov 20;23(1):893. doi: 10.1186/s12903-023-03508-8. PMID: 37985977Free PMC Article
Dong J, Ruan W, Duan X
Oral Dis 2023 Sep;29(6):2334-2365. Epub 2023 May 8 doi: 10.1111/odi.14599. PMID: 37154292
Kim YJ, Lee Y, Kasimoglu Y, Seymen F, Simmer JP, Hu JC, Cho ES, Kim JW
J Dent Res 2022 Jan;101(1):37-45. Epub 2021 May 26 doi: 10.1177/00220345211015119. PMID: 34036831Free PMC Article
Quandalle C, Boillot A, Fournier B, Garrec P, DE LA Dure-Molla M, Kerner S
J Appl Oral Sci 2020;28:e20200170. Epub 2020 Sep 28 doi: 10.1590/1678-7757-2020-0170. PMID: 32997085Free PMC Article
Adorno-Farias D, Ortega-Pinto A, Gajardo P, Salazar A, Morales-Bozo I, Werlinger F, Rojas-Flores S, Molina-Berríos A, Echeverría-López S, Jara-Sandoval J, Jara L, Urzúa B
J Appl Oral Sci 2019 Apr 1;27:e20180359. doi: 10.1590/1678-7757-2018-0359. PMID: 30970114Free PMC Article

Therapy

Nahsan FP, Silva LM, Lima TM, Bertocco VP, Chui FM, Martins LM
Gen Dent 2016 Nov-Dec;64(6):e6-e9. PMID: 27814261
Rogers HJ, Yesudian G, Rodd HD
Eur Arch Paediatr Dent 2016 Aug;17(4):271-5. Epub 2015 Oct 27 doi: 10.1007/s40368-015-0214-8. PMID: 26508432
Markovic D, Petrovic B, Peric T
Eur Arch Paediatr Dent 2010 Aug;11(4):201-8. doi: 10.1007/BF03262745. PMID: 20840832
Ashkenazi M, Blumer S, Eli I
Int J Paediatr Dent 2010 Jul;20(4):270-5. doi: 10.1111/j.1365-263X.2010.01049.x. PMID: 20536588
Phakey P, Palamara J, Hall RK, McCredie DA
Connect Tissue Res 1995;32(1-4):253-9. doi: 10.3109/03008209509013731. PMID: 7554924

Prognosis

Zhang Z, Zou X, Feng L, Huang Y, Chen F, Sun K, Song Y, Lv P, Gao X, Dong Y, Tian H
BMC Oral Health 2023 Nov 20;23(1):893. doi: 10.1186/s12903-023-03508-8. PMID: 37985977Free PMC Article
Nikolopoulos G, Smith CEL, Poulter JA, Murillo G, Silva S, Lamb T, Berry IR, Brown CJ, Day PF, Soldani F, Al-Bahlani S, Harris SA, O'Connell MJ, Inglehearn CF, Mighell AJ
Hum Mutat 2021 May;42(5):567-576. Epub 2021 Mar 6 doi: 10.1002/humu.24187. PMID: 33600052
Rey T, Tarabeux J, Gerard B, Delbarre M, Le Béchec A, Stoetzel C, Prasad M, Laugel-Haushalter V, Kawczynski M, Muller J, Chelly J, Dollfus H, Manière MC, Bloch-Zupan A
Methods Mol Biol 2019;1922:407-452. doi: 10.1007/978-1-4939-9012-2_36. PMID: 30838594
Chamarthi V, Varma BR, Jayanthi M
J Indian Soc Pedod Prev Dent 2012 Jan-Mar;30(1):70-3. doi: 10.4103/0970-4388.95587. PMID: 22565521
Witkop CJ Jr, Gundlach KK, Streed WJ, Sauk JJ Jr
Oral Surg Oral Med Oral Pathol 1976 Apr;41(4):472-83. doi: 10.1016/0030-4220(76)90275-9. PMID: 1063348

Clinical prediction guides

Zhang Z, Zou X, Feng L, Huang Y, Chen F, Sun K, Song Y, Lv P, Gao X, Dong Y, Tian H
BMC Oral Health 2023 Nov 20;23(1):893. doi: 10.1186/s12903-023-03508-8. PMID: 37985977Free PMC Article
Nikolopoulos G, Smith CEL, Poulter JA, Murillo G, Silva S, Lamb T, Berry IR, Brown CJ, Day PF, Soldani F, Al-Bahlani S, Harris SA, O'Connell MJ, Inglehearn CF, Mighell AJ
Hum Mutat 2021 May;42(5):567-576. Epub 2021 Mar 6 doi: 10.1002/humu.24187. PMID: 33600052
Quandalle C, Boillot A, Fournier B, Garrec P, DE LA Dure-Molla M, Kerner S
J Appl Oral Sci 2020;28:e20200170. Epub 2020 Sep 28 doi: 10.1590/1678-7757-2020-0170. PMID: 32997085Free PMC Article
Adorno-Farias D, Ortega-Pinto A, Gajardo P, Salazar A, Morales-Bozo I, Werlinger F, Rojas-Flores S, Molina-Berríos A, Echeverría-López S, Jara-Sandoval J, Jara L, Urzúa B
J Appl Oral Sci 2019 Apr 1;27:e20180359. doi: 10.1590/1678-7757-2018-0359. PMID: 30970114Free PMC Article
Zhang H, Koruyucu M, Seymen F, Kasimoglu Y, Kim JW, Tinawi S, Zhang C, Jacquemont ML, Vieira AR, Simmer JP, Hu JCC
J Dent Res 2019 May;98(5):541-548. Epub 2019 Feb 19 doi: 10.1177/0022034518824571. PMID: 30779877Free PMC Article

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