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Long palm

MedGen UID:
869005
Concept ID:
C4023422
Finding
HPO: HP:0011302

Definition

For children from birth to 16 years of age the length of the palm is more than the 97th centile; or, the length of the palm appears relatively long compared to the finger length or the limb length. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLong palm

Conditions with this feature

Syndromic X-linked intellectual disability Snyder type
MedGen UID:
162918
Concept ID:
C0796160
Disease or Syndrome
Snyder-Robinson syndrome (SRS) is an X-linked intellectual disability syndrome characterized by asthenic build, facial dysmorphism with a prominent lower lip, kyphoscoliosis, osteoporosis, speech abnormalities, and seizures. Developmental delay usually presents as failure to meet early developmental milestones and then evolves to moderate to profound intellectual disability (which appears to remain stable over time) and variable motor disability. Asthenic habitus and low muscle mass usually develop during the first year, even in males who are ambulatory. During the first decade, males with SRS develop osteoporosis, resulting in fractures in the absence of trauma.
Oculocerebrofacial syndrome, Kaufman type
MedGen UID:
343403
Concept ID:
C1855663
Disease or Syndrome
Kaufman oculocerebrofacial syndrome (KOS) is characterized by developmental delay, severe intellectual disability, and distinctive craniofacial features. Most affected children have prenatal-onset microcephaly, hypotonia, and growth deficiency. Feeding issues, ocular abnormalities, hearing impairment, and respiratory tract abnormalities are common. Ocular abnormalities can include structural abnormalities (microcornea or microphthalmia, coloboma, optic nerve hypoplasia), refractive errors (myopia ± astigmatism, hyperopia), strabismus, and entropion. Both conductive and sensorineural hearing loss have been reported as well as mixed conductive-sensorineural hearing loss of variable severity. Breathing problems can lead to prolonged hospitalization after birth in more than half of individuals. Less common findings include ectodermal abnormalities, cardiac manifestations, urogenital abnormalities, seizures, and skeletal abnormalities.
Syndromic X-linked intellectual disability 14
MedGen UID:
372646
Concept ID:
C1970822
Disease or Syndrome
Any X-linked syndromic intellectual disability in which the cause of the disease is a mutation in the UPF3B gene.

Professional guidelines

PubMed

LaTowsky B, Jacob C, Hibler BP, Lorenc PZ, Petraki C, Palm M
Dermatol Surg 2023 Apr 1;49(4S):S8-S14. Epub 2023 Mar 9 doi: 10.1097/DSS.0000000000003747. PMID: 37000913
Saguil A, Fargo M, Grogan S
Am Fam Physician 2015 Mar 15;91(6):365-71. PMID: 25822554
Obstet Gynecol 2013 Apr;121(4):891-896. doi: 10.1097/01.AOG.0000428646.67925.9a. PMID: 23635706

Recent clinical studies

Etiology

Monk BJ, Barretina-Ginesta MP, Pothuri B, Vergote I, Graybill W, Mirza MR, McCormick CC, Lorusso D, Moore RG, Freyer G, O'Cearbhaill RE, Heitz F, O'Malley DM, Redondo A, Shahin MS, Vulsteke C, Bradley WH, Haslund CA, Chase DM, Pisano C, Holman LL, Pérez MJR, DiSilvestro P, Gaba L, Herzog TJ, Bruchim I, Compton N, Shtessel L, Malinowska IA, González-Martín A
Ann Oncol 2024 Nov;35(11):981-992. Epub 2024 Sep 14 doi: 10.1016/j.annonc.2024.08.2241. PMID: 39284381
Ramgopal MN, Castagna A, Cazanave C, Diaz-Brito V, Dretler R, Oka S, Osiyemi O, Walmsley S, Sims J, Di Perri G, Sutton K, Sutherland-Phillips D, Berni A, Latham CL, Zhang F, D'Amico R, Pascual Bernáldez M, Van Solingen-Ristea R, Van Eygen V, Patel P, Chounta V, Spreen WR, Garges HP, Smith K, van Wyk J
Lancet HIV 2023 Sep;10(9):e566-e577. Epub 2023 Aug 8 doi: 10.1016/S2352-3018(23)00136-4. PMID: 37567205
Llibre JM, Brites C, Cheng CY, Osiyemi O, Galera C, Hocqueloux L, Maggiolo F, Degen O, Taylor S, Blair E, Man C, Wynne B, Oyee J, Underwood M, Curtis L, Bontempo G, van Wyk J
Clin Infect Dis 2023 Feb 18;76(4):720-729. doi: 10.1093/cid/ciac130. PMID: 35235656Free PMC Article
Krittanawong C, Isath A, Rosenson RS, Khawaja M, Wang Z, Fogg SE, Virani SS, Qi L, Cao Y, Long MT, Tangney CC, Lavie CJ
Am J Med 2022 Oct;135(10):1213-1230.e3. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.021. PMID: 35580715Free PMC Article
Wouk N, Helton M
Am Fam Physician 2019 Apr 1;99(7):435-443. PMID: 30932448

Diagnosis

Monk BJ, Barretina-Ginesta MP, Pothuri B, Vergote I, Graybill W, Mirza MR, McCormick CC, Lorusso D, Moore RG, Freyer G, O'Cearbhaill RE, Heitz F, O'Malley DM, Redondo A, Shahin MS, Vulsteke C, Bradley WH, Haslund CA, Chase DM, Pisano C, Holman LL, Pérez MJR, DiSilvestro P, Gaba L, Herzog TJ, Bruchim I, Compton N, Shtessel L, Malinowska IA, González-Martín A
Ann Oncol 2024 Nov;35(11):981-992. Epub 2024 Sep 14 doi: 10.1016/j.annonc.2024.08.2241. PMID: 39284381
COVIDSurg Collaborative; GlobalSurg Collaborative
Anaesthesia 2021 Jun;76(6):748-758. Epub 2021 Mar 9 doi: 10.1111/anae.15458. PMID: 33690889Free PMC Article
Wouk N, Helton M
Am Fam Physician 2019 Apr 1;99(7):435-443. PMID: 30932448
Saguil A, Fargo M, Grogan S
Am Fam Physician 2015 Mar 15;91(6):365-71. PMID: 25822554
Obstet Gynecol 2013 Apr;121(4):891-896. doi: 10.1097/01.AOG.0000428646.67925.9a. PMID: 23635706

Therapy

Monk BJ, Barretina-Ginesta MP, Pothuri B, Vergote I, Graybill W, Mirza MR, McCormick CC, Lorusso D, Moore RG, Freyer G, O'Cearbhaill RE, Heitz F, O'Malley DM, Redondo A, Shahin MS, Vulsteke C, Bradley WH, Haslund CA, Chase DM, Pisano C, Holman LL, Pérez MJR, DiSilvestro P, Gaba L, Herzog TJ, Bruchim I, Compton N, Shtessel L, Malinowska IA, González-Martín A
Ann Oncol 2024 Nov;35(11):981-992. Epub 2024 Sep 14 doi: 10.1016/j.annonc.2024.08.2241. PMID: 39284381
Ramgopal MN, Castagna A, Cazanave C, Diaz-Brito V, Dretler R, Oka S, Osiyemi O, Walmsley S, Sims J, Di Perri G, Sutton K, Sutherland-Phillips D, Berni A, Latham CL, Zhang F, D'Amico R, Pascual Bernáldez M, Van Solingen-Ristea R, Van Eygen V, Patel P, Chounta V, Spreen WR, Garges HP, Smith K, van Wyk J
Lancet HIV 2023 Sep;10(9):e566-e577. Epub 2023 Aug 8 doi: 10.1016/S2352-3018(23)00136-4. PMID: 37567205
Llibre JM, Brites C, Cheng CY, Osiyemi O, Galera C, Hocqueloux L, Maggiolo F, Degen O, Taylor S, Blair E, Man C, Wynne B, Oyee J, Underwood M, Curtis L, Bontempo G, van Wyk J
Clin Infect Dis 2023 Feb 18;76(4):720-729. doi: 10.1093/cid/ciac130. PMID: 35235656Free PMC Article
Krittanawong C, Isath A, Rosenson RS, Khawaja M, Wang Z, Fogg SE, Virani SS, Qi L, Cao Y, Long MT, Tangney CC, Lavie CJ
Am J Med 2022 Oct;135(10):1213-1230.e3. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.021. PMID: 35580715Free PMC Article
Pascual G, Domínguez D, Elosúa-Bayes M, Beckedorff F, Laudanna C, Bigas C, Douillet D, Greco C, Symeonidi A, Hernández I, Gil SR, Prats N, Bescós C, Shiekhattar R, Amit M, Heyn H, Shilatifard A, Benitah SA
Nature 2021 Nov;599(7885):485-490. Epub 2021 Nov 10 doi: 10.1038/s41586-021-04075-0. PMID: 34759321

Prognosis

Monk BJ, Barretina-Ginesta MP, Pothuri B, Vergote I, Graybill W, Mirza MR, McCormick CC, Lorusso D, Moore RG, Freyer G, O'Cearbhaill RE, Heitz F, O'Malley DM, Redondo A, Shahin MS, Vulsteke C, Bradley WH, Haslund CA, Chase DM, Pisano C, Holman LL, Pérez MJR, DiSilvestro P, Gaba L, Herzog TJ, Bruchim I, Compton N, Shtessel L, Malinowska IA, González-Martín A
Ann Oncol 2024 Nov;35(11):981-992. Epub 2024 Sep 14 doi: 10.1016/j.annonc.2024.08.2241. PMID: 39284381
Rauen T, Wied S, Fitzner C, Eitner F, Sommerer C, Zeier M, Otte B, Panzer U, Budde K, Benck U, Mertens PR, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann JFE, Hilgers RD, Floege J; STOP-IgAN Investigators
Kidney Int 2020 Oct;98(4):1044-1052. Epub 2020 May 22 doi: 10.1016/j.kint.2020.04.046. PMID: 32450154
Pravda J
Discov Med 2019 May;27(149):197-200. PMID: 31361982
Kordyukova LV, Serebryakova MV, Khrustalev VV, Veit M
Protein Pept Lett 2019;26(8):588-600. doi: 10.2174/0929866526666190603082521. PMID: 31161979
HPS3/TIMI55–REVEAL Collaborative Group, Bowman L, Hopewell JC, Chen F, Wallendszus K, Stevens W, Collins R, Wiviott SD, Cannon CP, Braunwald E, Sammons E, Landray MJ
N Engl J Med 2017 Sep 28;377(13):1217-1227. Epub 2017 Aug 28 doi: 10.1056/NEJMoa1706444. PMID: 28847206

Clinical prediction guides

Monk BJ, Barretina-Ginesta MP, Pothuri B, Vergote I, Graybill W, Mirza MR, McCormick CC, Lorusso D, Moore RG, Freyer G, O'Cearbhaill RE, Heitz F, O'Malley DM, Redondo A, Shahin MS, Vulsteke C, Bradley WH, Haslund CA, Chase DM, Pisano C, Holman LL, Pérez MJR, DiSilvestro P, Gaba L, Herzog TJ, Bruchim I, Compton N, Shtessel L, Malinowska IA, González-Martín A
Ann Oncol 2024 Nov;35(11):981-992. Epub 2024 Sep 14 doi: 10.1016/j.annonc.2024.08.2241. PMID: 39284381
Llibre JM, Brites C, Cheng CY, Osiyemi O, Galera C, Hocqueloux L, Maggiolo F, Degen O, Taylor S, Blair E, Man C, Wynne B, Oyee J, Underwood M, Curtis L, Bontempo G, van Wyk J
Clin Infect Dis 2023 Feb 18;76(4):720-729. doi: 10.1093/cid/ciac130. PMID: 35235656Free PMC Article
Krittanawong C, Isath A, Rosenson RS, Khawaja M, Wang Z, Fogg SE, Virani SS, Qi L, Cao Y, Long MT, Tangney CC, Lavie CJ
Am J Med 2022 Oct;135(10):1213-1230.e3. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.021. PMID: 35580715Free PMC Article
Wallace TC
J Am Coll Nutr 2019 Feb;38(2):97-107. Epub 2018 Nov 5 doi: 10.1080/07315724.2018.1497562. PMID: 30395784
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators
N Engl J Med 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. PMID: 24450891Free PMC Article

Recent systematic reviews

Buckley BJ, Long L, Risom SS, Lane DA, Berg SK, Gluud C, Palm P, Sibilitz KL, Svendsen JH, Zwisler AD, Lip GY, Neubeck L, Taylor RS
Cochrane Database Syst Rev 2024 Sep 17;9(9):CD011197. doi: 10.1002/14651858.CD011197.pub3. PMID: 39287086Free PMC Article
Voon PT, Ng CM, Ng YT, Wong YJ, Yap SY, Leong SL, Yong XS, Lee SWH
Adv Nutr 2024 Sep;15(9):100276. Epub 2024 Jul 23 doi: 10.1016/j.advnut.2024.100276. PMID: 39053603Free PMC Article
Franco JV, Trivisonno L, Sgarbossa NJ, Alvez GA, Fieiras C, Escobar Liquitay CM, Jung JH
Cochrane Database Syst Rev 2023 Jun 22;6(6):CD001423. doi: 10.1002/14651858.CD001423.pub4. PMID: 37345871Free PMC Article
Schmüdderich K, Kiwitt J, Palm R, Roes M, Holle B
J Clin Nurs 2023 May;32(9-10):1858-1884. Epub 2022 Feb 4 doi: 10.1111/jocn.16231. PMID: 35122351
Krittanawong C, Isath A, Rosenson RS, Khawaja M, Wang Z, Fogg SE, Virani SS, Qi L, Cao Y, Long MT, Tangney CC, Lavie CJ
Am J Med 2022 Oct;135(10):1213-1230.e3. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.021. PMID: 35580715Free PMC Article

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