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Elevated urinary dopamine level

MedGen UID:
868696
Concept ID:
C4023099
Finding
Synonym: Elevated urinary dopamine
 
HPO: HP:0011979

Definition

The concentration of dopamine in the urine, normalized for urine concentration, is above the upper limit of normal. [from HPO]

Term Hierarchy

Conditions with this feature

Multiple endocrine neoplasia type 2A
MedGen UID:
9958
Concept ID:
C0025268
Neoplastic Process
Multiple endocrine neoplasia type 2 (MEN2) includes the following phenotypes: MEN2A, FMTC (familial medullary thyroid carcinoma, which may be a variant of MEN2A), and MEN2B. All three phenotypes involve high risk for development of medullary carcinoma of the thyroid (MTC); MEN2A and MEN2B involve an increased risk for pheochromocytoma; MEN2A involves an increased risk for parathyroid adenoma or hyperplasia. Additional features in MEN2B include mucosal neuromas of the lips and tongue, distinctive facies with enlarged lips, ganglioneuromatosis of the gastrointestinal tract, and a marfanoid habitus. MTC typically occurs in early childhood in MEN2B, early adulthood in MEN2A, and middle age in FMTC.
Neuroblastoma, susceptibility to, 1
MedGen UID:
412713
Concept ID:
C2749485
Finding

Professional guidelines

PubMed

Liu Y , Liu Z , Wei M , Hu M , Yue K , Bi R , Zhai S , Pi Z , Song F , Liu Z
Food Funct 2019 Jan 22;10(1):432-447. doi: 10.1039/c8fo02067a. PMID: 30623955
Zhang J, Rössle M, Zhou X, Deng J, Liu L, Qi X
Curr Med Res Opin 2019 May;35(5):859-868. Epub 2019 Jan 4 doi: 10.1080/03007995.2018.1552575. PMID: 30474439
Alvarado CS, Faraj BA, Kim TH, Camp VM, Bain RP, Ragab AH
Am J Pediatr Hematol Oncol 1985 Fall;7(3):221-7. doi: 10.1097/00043426-198507030-00002. PMID: 3934994

Recent clinical studies

Etiology

Zhu K, Liu Q, Xie X, Jiang Q, Feng Y, Xiao P, Wu X, Zhu B, Song R
Neurotoxicology 2022 Sep;92:102-109. Epub 2022 Aug 5 doi: 10.1016/j.neuro.2022.08.004. PMID: 35940320
Verly IRN, Matser YAH, Leen R, Meinsma R, Fiocco M, Koster J, Volckmann R, Savci-Heijink D, Cangemi G, Barco S, Valentijn LJ, Tytgat GAM, van Kuilenburg ABP
JCO Precis Oncol 2022 Jan;6:e2000447. doi: 10.1200/PO.20.00447. PMID: 35085004Free PMC Article
De Luca M, Bryan DR, Hunter GR
Biomolecules 2021 Feb 24;11(3) doi: 10.3390/biom11030342. PMID: 33668381Free PMC Article
Pirojsakul K, Thanapinyo A, Nuntnarumit P
Pediatr Nephrol 2017 Jun;32(6):1053-1058. Epub 2017 Feb 11 doi: 10.1007/s00467-017-3586-7. PMID: 28190246
Vanitallie TB
Metabolism 2002 Jun;51(6 Suppl 1):40-5. doi: 10.1053/meta.2002.33191. PMID: 12040540

Diagnosis

Feelders RA, Fleseriu M, Kadioglu P, Bex M, González-Devia D, Boguszewski CL, Yavuz DG, Patino H, Pedroncelli AM, Maamari R, Chattopadhyay A, Biller BMK, Pivonello R
Front Endocrinol (Lausanne) 2023;14:1165681. Epub 2023 Oct 9 doi: 10.3389/fendo.2023.1165681. PMID: 37876540Free PMC Article
Verly IRN, Matser YAH, Leen R, Meinsma R, Fiocco M, Koster J, Volckmann R, Savci-Heijink D, Cangemi G, Barco S, Valentijn LJ, Tytgat GAM, van Kuilenburg ABP
JCO Precis Oncol 2022 Jan;6:e2000447. doi: 10.1200/PO.20.00447. PMID: 35085004Free PMC Article
Sasaki S, Yasuda T, Kaneto H, Otsuki M, Tabuchi Y, Fujita Y, Kubo F, Tsuji M, Fujisawa K, Kasami R, Kitamura T, Miyatsuka T, Katakami N, Kawamori D, Matsuoka TA, Imagawa A, Shimomura I
Intern Med 2012;51(17):2365-70. Epub 2012 Sep 1 doi: 10.2169/internalmedicine.51.7726. PMID: 22975550
Robertson D, Beck C, Gary T, Picklo M
Int Angiol 1993 Jun;12(2):93-102. PMID: 8371002
Naschitz JE, Yeshurun D, Shahar J
Angiology 1990 Nov;41(11):893-900. doi: 10.1177/000331979004101101. PMID: 2244692

Therapy

Feelders RA, Fleseriu M, Kadioglu P, Bex M, González-Devia D, Boguszewski CL, Yavuz DG, Patino H, Pedroncelli AM, Maamari R, Chattopadhyay A, Biller BMK, Pivonello R
Front Endocrinol (Lausanne) 2023;14:1165681. Epub 2023 Oct 9 doi: 10.3389/fendo.2023.1165681. PMID: 37876540Free PMC Article
Zhu K, Liu Q, Xie X, Jiang Q, Feng Y, Xiao P, Wu X, Zhu B, Song R
Neurotoxicology 2022 Sep;92:102-109. Epub 2022 Aug 5 doi: 10.1016/j.neuro.2022.08.004. PMID: 35940320
Zhang J, Rössle M, Zhou X, Deng J, Liu L, Qi X
Curr Med Res Opin 2019 May;35(5):859-868. Epub 2019 Jan 4 doi: 10.1080/03007995.2018.1552575. PMID: 30474439
Naschitz JE, Yeshurun D, Shahar J
Angiology 1990 Nov;41(11):893-900. doi: 10.1177/000331979004101101. PMID: 2244692
Feldman JM
J Clin Pharmacol 1987 Apr;27(4):288-92. doi: 10.1002/j.1552-4604.1987.tb03015.x. PMID: 3680586

Prognosis

Verly IRN, Matser YAH, Leen R, Meinsma R, Fiocco M, Koster J, Volckmann R, Savci-Heijink D, Cangemi G, Barco S, Valentijn LJ, Tytgat GAM, van Kuilenburg ABP
JCO Precis Oncol 2022 Jan;6:e2000447. doi: 10.1200/PO.20.00447. PMID: 35085004Free PMC Article
Desir GV
Curr Opin Nephrol Hypertens 2011 Jan;20(1):31-6. doi: 10.1097/MNH.0b013e3283412721. PMID: 21099685
Vanitallie TB
Metabolism 2002 Jun;51(6 Suppl 1):40-5. doi: 10.1053/meta.2002.33191. PMID: 12040540
Naschitz JE, Yeshurun D, Shahar J
Angiology 1990 Nov;41(11):893-900. doi: 10.1177/000331979004101101. PMID: 2244692
LaBrosse EH, Comoy E, Bohuon C, Zucker JM, Schweisguth O
J Natl Cancer Inst 1976 Sep;57(3):633-8. doi: 10.1093/jnci/57.3.633. PMID: 10450

Clinical prediction guides

Verly IRN, Matser YAH, Leen R, Meinsma R, Fiocco M, Koster J, Volckmann R, Savci-Heijink D, Cangemi G, Barco S, Valentijn LJ, Tytgat GAM, van Kuilenburg ABP
JCO Precis Oncol 2022 Jan;6:e2000447. doi: 10.1200/PO.20.00447. PMID: 35085004Free PMC Article
De Luca M, Bryan DR, Hunter GR
Biomolecules 2021 Feb 24;11(3) doi: 10.3390/biom11030342. PMID: 33668381Free PMC Article
Desir GV
Curr Opin Nephrol Hypertens 2011 Jan;20(1):31-6. doi: 10.1097/MNH.0b013e3283412721. PMID: 21099685
Vanitallie TB
Metabolism 2002 Jun;51(6 Suppl 1):40-5. doi: 10.1053/meta.2002.33191. PMID: 12040540
Naschitz JE, Yeshurun D, Shahar J
Angiology 1990 Nov;41(11):893-900. doi: 10.1177/000331979004101101. PMID: 2244692

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