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Abnormal sperm tail morphology

MedGen UID:
868305
Concept ID:
C4022699
Finding
Synonym: Sperm tail anomaly
 
HPO: HP:0012868

Definition

A structural abnormality of the sperm tail. [from HPO]

Conditions with this feature

Deafness-infertility syndrome
MedGen UID:
370197
Concept ID:
C1970187
Disease or Syndrome
CATSPER-related male infertility results from abnormalities in sperm and can be either CATSPER-related nonsyndromic male infertility (NSMI) or the deafness-infertility syndrome (DIS) when associated with non-progressive prelingual sensorineural hearing loss. Males with NSMI have infertility while females have no symptoms. Males with DIS have both infertility and hearing loss, while females have only hearing loss. Routine semen analysis typically identifies abnormalities in sperm number, morphology, and motility. Otologic examination and audiologic assessment can identify hearing loss.

Professional guidelines

PubMed

Lasiene K, Gedrimas V, Vitkus A, Glinskyte S, Lasys V, Valanciute A, Sienkiewicz W
Pol J Vet Sci 2013;16(4):773-85. doi: 10.2478/pjvs-2013-0112. PMID: 24597318
Klysik M
Pathol Res Pract 2008;204(2):77-88. doi: 10.1016/j.prp.2007.10.013. PMID: 18312782
Bartoov B, Eltes F, Reichart M, Langzam J, Lederman H, Zabludovsky N
Arch Androl 1999 May-Jun;42(3):161-77. doi: 10.1080/014850199262823. PMID: 10407647

Recent clinical studies

Etiology

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Sasi SM, Alghoul NM, Awayn N, Elghoul A, Prastiya RA
Open Vet J 2023 Jul;13(7):873-878. Epub 2023 Jul 31 doi: 10.5455/OVJ.2023.v13.i7.9. PMID: 37614725Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF
Hum Reprod Update 2015 Jul-Aug;21(4):455-85. Epub 2015 Apr 17 doi: 10.1093/humupd/dmv020. PMID: 25888788

Diagnosis

Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Kumar N, Singh AK
Biol Reprod 2021 Mar 11;104(3):508-520. doi: 10.1093/biolre/ioaa213. PMID: 33238303
Sha YW, Ding L, Wu JX, Lin SB, Wang X, Ji ZY, Li P
Andrologia 2017 Oct;49(8) Epub 2016 Oct 6 doi: 10.1111/and.12716. PMID: 27709648
Pereira R, Sá R, Barros A, Sousa M
Asian J Androl 2017 Jan-Feb;19(1):5-14. doi: 10.4103/1008-682X.167716. PMID: 26680031Free PMC Article
Klysik M
Pathol Res Pract 2008;204(2):77-88. doi: 10.1016/j.prp.2007.10.013. PMID: 18312782

Therapy

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Adamczak R, Ukleja-Sokołowska N, Pasińska M, Zielińska J, Leśny M, Dubiel M
Int J Immunopathol Pharmacol 2022 Jan-Dec;36:20587384211066718. doi: 10.1177/20587384211066718. PMID: 34984934Free PMC Article
Pereira R, Sá R, Barros A, Sousa M
Asian J Androl 2017 Jan-Feb;19(1):5-14. doi: 10.4103/1008-682X.167716. PMID: 26680031Free PMC Article
Auger J, Jouannet P, Eustache F
Hum Reprod 2016 Jan;31(1):10-23. Epub 2015 Oct 14 doi: 10.1093/humrep/dev251. PMID: 26472152
Afzelius BA
Am J Hum Genet 1981 Nov;33(6):852-64. PMID: 7034533Free PMC Article

Prognosis

Nguyen ND, Le MT, Dang HNT, Van Nguyen T, Nguyen QHV, Cao TN
J Int Med Res 2023 Aug;51(8):3000605231188655. doi: 10.1177/03000605231188655. PMID: 37572034Free PMC Article
Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF
Hum Reprod Update 2015 Jul-Aug;21(4):455-85. Epub 2015 Apr 17 doi: 10.1093/humupd/dmv020. PMID: 25888788

Clinical prediction guides

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Nassir M, Levi M, Dardikman-Yoffe G, Mirsky SK, Shaked NT
Cells 2022 Apr 13;11(8) doi: 10.3390/cells11081319. PMID: 35455999Free PMC Article
Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article

Recent systematic reviews

Mazaheri Moghaddam M, Mazaheri Moghaddam M, Hamzeiy H, Baghbanzadeh A, Pashazadeh F, Sakhinia E
J Assist Reprod Genet 2021 Mar;38(3):573-586. Epub 2021 Jan 15 doi: 10.1007/s10815-020-02008-w. PMID: 33452591Free PMC Article
Girardet L, Augière C, Asselin MP, Belleannée C
Andrology 2019 Sep;7(5):588-602. Epub 2019 May 26 doi: 10.1111/andr.12650. PMID: 31131532
Lotti F, Maggi M
Hum Reprod Update 2015 Jan-Feb;21(1):56-83. Epub 2014 Jul 19 doi: 10.1093/humupd/dmu042. PMID: 25038770

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