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Abnormal lower-limb motor evoked potentials

MedGen UID:
866711
•Concept ID:
C4021058
•
Pathologic Function
Synonym: Abnormal motor evoked potentials in the lower limb
 
HPO: HP:0012898

Definition

An anomaly identified by motor evoked potentials (MEPs) in the leg. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal lower-limb motor evoked potentials

Professional guidelines

PubMed

The role of electrophysiology in the diagnosis and management of cervical spondylotic myelopathy.
Lo YL
Ann Acad Med Singap 2007 Nov;36(11):886-93. PMID: 18071594

Recent clinical studies

Etiology

Coupling motor evoked potentials and brain [(18)F]FDG-PET in Amyotrophic Lateral Sclerosis: preliminary findings on disease severity.
Tondo G, Mazzini L, Caminiti SP, Gallo C, Matheoud R, Comi C, Sacchetti GM, Perani D, De Marchi F
Neurobiol Dis 2024 Sep;199:106579. Epub 2024 Jun 25 doi: 10.1016/j.nbd.2024.106579. PMID: 38936435
Cortical excitability changes in patients of vascular parkinsonism with cognitive impairment.
Agrawal A, Bhattacharya A, Kamble N, Mailankody P, Yadav R, Pal PK
Parkinsonism Relat Disord 2023 Nov;116:105869. Epub 2023 Sep 26 doi: 10.1016/j.parkreldis.2023.105869. PMID: 37783026
Evoked potentials as biomarkers of hereditary spastic paraplegias: A case-control study.
Brighente SF, Vicuña P, Rodrigues Louzada AL, Giordani GM, Fussiger H, Dos Santos MAR, Cubillos-Arcila DM, Winckler PB, Saute JAM
PLoS One 2021;16(11):e0259397. Epub 2021 Nov 30 doi: 10.1371/journal.pone.0259397. PMID: 34847171Free PMC Article
Focal chronic inflammatory demyelinating polyradiculoneuropathy: Onset, course, and distinct features.
Benoit C, Svahn J, Debs R, Vandendries C, Lenglet T, Zyss J, Maisonobe T, Viala K
J Peripher Nerv Syst 2021 Jun;26(2):193-201. Epub 2021 Mar 16 doi: 10.1111/jns.12438. PMID: 33660880
Clinical correlations of motor and somatosensory evoked potentials in neuromyelitis optica.
Tsao WC, Lyu RK, Ro LS, Lao MF, Chen CM, Wu YR, Huang CC, Chang HS, Kuo HC, Chu CC, Chang KH
PLoS One 2014;9(11):e113631. Epub 2014 Nov 25 doi: 10.1371/journal.pone.0113631. PMID: 25422930Free PMC Article

Diagnosis

Coupling motor evoked potentials and brain [(18)F]FDG-PET in Amyotrophic Lateral Sclerosis: preliminary findings on disease severity.
Tondo G, Mazzini L, Caminiti SP, Gallo C, Matheoud R, Comi C, Sacchetti GM, Perani D, De Marchi F
Neurobiol Dis 2024 Sep;199:106579. Epub 2024 Jun 25 doi: 10.1016/j.nbd.2024.106579. PMID: 38936435
Electrodiagnostic findings in facial onset sensory motor neuronopathy (FOSMN).
De Oliveira HM, Silsby M, Jaiser SR, Lai HM, Pavey N, Kiernan MC, Williams TL, Vucic S, Baker MR
Clin Neurophysiol 2022 Aug;140:228-238. Epub 2022 May 10 doi: 10.1016/j.clinph.2022.04.020. PMID: 35599162
Evoked potentials as biomarkers of hereditary spastic paraplegias: A case-control study.
Brighente SF, Vicuña P, Rodrigues Louzada AL, Giordani GM, Fussiger H, Dos Santos MAR, Cubillos-Arcila DM, Winckler PB, Saute JAM
PLoS One 2021;16(11):e0259397. Epub 2021 Nov 30 doi: 10.1371/journal.pone.0259397. PMID: 34847171Free PMC Article
Upper limb motor evoked potentials as outcome measure in progressive multiple sclerosis.
Pisa M, Chieffo R, Giordano A, Gelibter S, Comola M, Comi G, Leocani L
Clin Neurophysiol 2020 Feb;131(2):401-405. Epub 2019 Dec 10 doi: 10.1016/j.clinph.2019.11.024. PMID: 31869704
Clinical correlations of motor and somatosensory evoked potentials in neuromyelitis optica.
Tsao WC, Lyu RK, Ro LS, Lao MF, Chen CM, Wu YR, Huang CC, Chang HS, Kuo HC, Chu CC, Chang KH
PLoS One 2014;9(11):e113631. Epub 2014 Nov 25 doi: 10.1371/journal.pone.0113631. PMID: 25422930Free PMC Article

Therapy

Cortical somatosensory processing after botulinum toxin therapy in post-stroke spasticity.
Veverka T, Hluštík P, Otruba P, Hok P, Opavský R, Zapletalová J, Kaňovský P
Medicine (Baltimore) 2021 Jun 25;100(25):e26356. doi: 10.1097/MD.0000000000026356. PMID: 34160405Free PMC Article
Spinal direct current stimulation (tsDCS) in hereditary spastic paraplegias (HSP): A sham-controlled crossover study.
Ardolino G, Bocci T, Nigro M, Vergari M, Di Fonzo A, Bonato S, Cogiamanian F, Cortese F, Cova I, Barbieri S, Priori A
J Spinal Cord Med 2021 Jan;44(1):46-53. Epub 2018 Dec 3 doi: 10.1080/10790268.2018.1543926. PMID: 30508408Free PMC Article
The role of sensory and motor evoked potentials in the prognosis of Pott's paraplegia.
Misra UK, Kalita J
Clin Neurophysiol 2004 Oct;115(10):2267-73. doi: 10.1016/j.clinph.2004.05.013. PMID: 15351368
Combined monitoring of motor and somatosensory evoked potentials in orthopaedic spinal surgery.
Pelosi L, Lamb J, Grevitt M, Mehdian SM, Webb JK, Blumhardt LD
Clin Neurophysiol 2002 Jul;113(7):1082-91. doi: 10.1016/s1388-2457(02)00027-5. PMID: 12088704
Motor evoked potentials and disability in secondary progressive multiple sclerosis.
Facchetti D, Mai R, Micheli A, Marcianó N, Capra R, Gasparotti R, Poloni M
Can J Neurol Sci 1997 Nov;24(4):332-7. doi: 10.1017/s0317167100033011. PMID: 9398981

Prognosis

Cortical somatosensory processing after botulinum toxin therapy in post-stroke spasticity.
Veverka T, Hluštík P, Otruba P, Hok P, Opavský R, Zapletalová J, Kaňovský P
Medicine (Baltimore) 2021 Jun 25;100(25):e26356. doi: 10.1097/MD.0000000000026356. PMID: 34160405Free PMC Article
Focal chronic inflammatory demyelinating polyradiculoneuropathy: Onset, course, and distinct features.
Benoit C, Svahn J, Debs R, Vandendries C, Lenglet T, Zyss J, Maisonobe T, Viala K
J Peripher Nerv Syst 2021 Jun;26(2):193-201. Epub 2021 Mar 16 doi: 10.1111/jns.12438. PMID: 33660880
Clinical, electrodiagnostic, and outcome correlation in ALS patients in Thailand.
Kulkantrakorn K, Suksasunee D
J Clin Neurosci 2017 Sep;43:165-169. Epub 2017 Jun 8 doi: 10.1016/j.jocn.2017.05.034. PMID: 28602631
Clinical correlations of motor and somatosensory evoked potentials in neuromyelitis optica.
Tsao WC, Lyu RK, Ro LS, Lao MF, Chen CM, Wu YR, Huang CC, Chang HS, Kuo HC, Chu CC, Chang KH
PLoS One 2014;9(11):e113631. Epub 2014 Nov 25 doi: 10.1371/journal.pone.0113631. PMID: 25422930Free PMC Article
Combined monitoring of motor and somatosensory evoked potentials in orthopaedic spinal surgery.
Pelosi L, Lamb J, Grevitt M, Mehdian SM, Webb JK, Blumhardt LD
Clin Neurophysiol 2002 Jul;113(7):1082-91. doi: 10.1016/s1388-2457(02)00027-5. PMID: 12088704

Clinical prediction guides

Cortical somatosensory processing after botulinum toxin therapy in post-stroke spasticity.
Veverka T, Hluštík P, Otruba P, Hok P, Opavský R, Zapletalová J, Kaňovský P
Medicine (Baltimore) 2021 Jun 25;100(25):e26356. doi: 10.1097/MD.0000000000026356. PMID: 34160405Free PMC Article
TMS-induced motor evoked potentials in Wilson's disease: a systematic literature review.
Bembenek JP, Kurczych K, Członkowska A
Bioelectromagnetics 2015 Apr;36(4):255-66. Epub 2015 Mar 23 doi: 10.1002/bem.21909. PMID: 25808411
Clinical correlations of motor and somatosensory evoked potentials in neuromyelitis optica.
Tsao WC, Lyu RK, Ro LS, Lao MF, Chen CM, Wu YR, Huang CC, Chang HS, Kuo HC, Chu CC, Chang KH
PLoS One 2014;9(11):e113631. Epub 2014 Nov 25 doi: 10.1371/journal.pone.0113631. PMID: 25422930Free PMC Article
Locomotor patterns in cerebellar ataxia.
Martino G, Ivanenko YP, Serrao M, Ranavolo A, d'Avella A, Draicchio F, Conte C, Casali C, Lacquaniti F
J Neurophysiol 2014 Dec 1;112(11):2810-21. Epub 2014 Sep 3 doi: 10.1152/jn.00275.2014. PMID: 25185815
Clinical aspects of premotor function.
Freund HJ
Behav Brain Res 1985 Nov-Dec;18(2):187-91. doi: 10.1016/0166-4328(85)90074-9. PMID: 3913445

Recent systematic reviews

TMS-induced motor evoked potentials in Wilson's disease: a systematic literature review.
Bembenek JP, Kurczych K, Członkowska A
Bioelectromagnetics 2015 Apr;36(4):255-66. Epub 2015 Mar 23 doi: 10.1002/bem.21909. PMID: 25808411

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