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Glomerulocystic Disease

MedGen UID:
866466
•Concept ID:
C4020705
•
Disease or Syndrome
Synonym: Glomerulocystic kidney disease

Definition

A condition characterized by dilatation of the Bowman space and affecting more than 5% of the glomeruli. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlomerulocystic Disease

Professional guidelines

PubMed

High-resolution ultrasonography in the differential diagnosis of cystic diseases of the kidney in infancy and childhood: preliminary experience.
Jain M, LeQuesne GW, Bourne AJ, Henning P
J Ultrasound Med 1997 Apr;16(4):235-40. doi: 10.7863/jum.1997.16.4.235. PMID: 9315149

Recent clinical studies

Etiology

Case Report: Variable Pharmacokinetic Profile of Eculizumab in an aHUS Patient.
Bouwmeester RN, Ter Avest M, Wijnsma KL, Duineveld C, Ter Heine R, Volokhina EB, Van Den Heuvel LPWJ, Wetzels JFM, van de Kar NCAJ
Front Immunol 2020;11:612706. Epub 2021 Jan 15 doi: 10.3389/fimmu.2020.612706. PMID: 33519821Free PMC Article
Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease.
Davis ID, Ho M, Hupertz V, Avner ED
Pediatr Transplant 2003 Oct;7(5):364-9. doi: 10.1034/j.1399-3046.2003.00094.x. PMID: 14738296
Renal cystic disease of infancy: results of histochemical studies. A report of the Southwest Pediatric Nephrology Study Group.
Verani R, Walker P, Silva FG
Pediatr Nephrol 1989 Jan;3(1):37-42. doi: 10.1007/BF00859623. PMID: 2702085
Polycystic kidney disease in the first year of life.
Cole BR, Conley SB, Stapleton FB
J Pediatr 1987 Nov;111(5):693-9. doi: 10.1016/s0022-3476(87)80244-5. PMID: 3668738
Glomerulocystic disease - a case report with 10 year follow-up.
Reznik VM, Griswold WT, Mendoza SA
Int J Pediatr Nephrol 1982 Dec;3(4):321-3. PMID: 7166457

Diagnosis

Neonatal stroke and haematuria: Answers.
Kellett S, Lemaire M, Miller SP, Licht C, Yoon G, Dlamini N, Noone D
Pediatr Nephrol 2018 May;33(5):807-811. Epub 2017 Jul 17 doi: 10.1007/s00467-017-3747-8. PMID: 28717939
Glomerulocystic disease.
Vijayakumar M, Prahlad N, Nammalwar BR
Indian Pediatr 2006 May;43(5):434-7. PMID: 16735768
Diffuse bilateral glomerulocystic disease of the kidneys and multiple cardiac rhabdomyomas in a newborn. Relationship with tuberous sclerosis and review of the literature.
Saguem MH, Laarif M, Remadi S, Bozakoura C, Cox JN
Pathol Res Pract 1992 Apr;188(3):367-73; discussion 373-4. doi: 10.1016/S0344-0338(11)81222-7. PMID: 1626000
Renal tubular acidosis in childhood.
Tsau YK, Chen CH, Tsai WS, Chiou YM
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1990 Jul-Aug;31(4):205-13. PMID: 2264480
Neonatal adrenoleukodystrophy: new cases, biochemical studies, and differentiation from Zellweger and related peroxisomal polydystrophy syndromes.
Kelley RI, Datta NS, Dobyns WB, Hajra AK, Moser AB, Noetzel MJ, Zackai EH, Moser HW
Am J Med Genet 1986 Apr;23(4):869-901. doi: 10.1002/ajmg.1320230404. PMID: 3515938

Therapy

Case Report: Variable Pharmacokinetic Profile of Eculizumab in an aHUS Patient.
Bouwmeester RN, Ter Avest M, Wijnsma KL, Duineveld C, Ter Heine R, Volokhina EB, Van Den Heuvel LPWJ, Wetzels JFM, van de Kar NCAJ
Front Immunol 2020;11:612706. Epub 2021 Jan 15 doi: 10.3389/fimmu.2020.612706. PMID: 33519821Free PMC Article
Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease.
Davis ID, Ho M, Hupertz V, Avner ED
Pediatr Transplant 2003 Oct;7(5):364-9. doi: 10.1034/j.1399-3046.2003.00094.x. PMID: 14738296
Polycystic kidney disease in the first year of life.
Cole BR, Conley SB, Stapleton FB
J Pediatr 1987 Nov;111(5):693-9. doi: 10.1016/s0022-3476(87)80244-5. PMID: 3668738

Prognosis

Glomerulocystic disease, a rare cause of renal cysts in infants: A series of three cases.
Islam N, Mandal B, Bera G, Mukherjee S, Chatterjee U
Indian J Pathol Microbiol 2019 Jan-Mar;62(1):95-98. doi: 10.4103/IJPM.IJPM_643_17. PMID: 30706867
The triad of nesidioblastosis, congenital neuroblastoma and glomerulocystic disease of the newborn: a case report.
Bulun A, Sarici SU, Soyer OU, Tekşam O, Yurdakök M, Cağlar M
Turk J Pediatr 2005 Jul-Sep;47(3):298-302. PMID: 16250322
Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease.
Davis ID, Ho M, Hupertz V, Avner ED
Pediatr Transplant 2003 Oct;7(5):364-9. doi: 10.1034/j.1399-3046.2003.00094.x. PMID: 14738296
Morphometric studies of cystic and tubulointerstitial kidney diseases with hepatic fibrosis in children.
Landing BH, Wells TR, Lipsey AI, Oyemade OA
Pediatr Pathol 1990;10(6):959-72. doi: 10.3109/15513819009064730. PMID: 2082340
Polycystic kidney disease in the first year of life.
Cole BR, Conley SB, Stapleton FB
J Pediatr 1987 Nov;111(5):693-9. doi: 10.1016/s0022-3476(87)80244-5. PMID: 3668738

Clinical prediction guides

Case Report: Variable Pharmacokinetic Profile of Eculizumab in an aHUS Patient.
Bouwmeester RN, Ter Avest M, Wijnsma KL, Duineveld C, Ter Heine R, Volokhina EB, Van Den Heuvel LPWJ, Wetzels JFM, van de Kar NCAJ
Front Immunol 2020;11:612706. Epub 2021 Jan 15 doi: 10.3389/fimmu.2020.612706. PMID: 33519821Free PMC Article
Pathogenic role of glomerulo-tubular junction stenosis in glomerulocystic disease.
Hotta O, Sato M, Furuta T, Taguma Y
Clin Nephrol 1999 Mar;51(3):177-80. PMID: 10099890

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