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J wave

MedGen UID:
866319
Concept ID:
C4018858
Finding
Synonyms: EKG J waves; Osborne waves
 
HPO: HP:0012272

Definition

The J wave is a positive convex deflection that occurs at the junction of the QRS complex and ST segment, the J-point. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJ wave

Conditions with this feature

Brugada syndrome 3
MedGen UID:
395633
Concept ID:
C2678478
Disease or Syndrome
Brugada syndrome is characterized by cardiac conduction abnormalities (ST segment abnormalities in leads V1-V3 on EKG and a high risk for ventricular arrhythmias) that can result in sudden death. Brugada syndrome presents primarily during adulthood, although age at diagnosis may range from infancy to late adulthood. The mean age of sudden death is approximately 40 years. Clinical presentations may also include sudden infant death syndrome (SIDS; death of a child during the first year of life without an identifiable cause) and sudden unexpected nocturnal death syndrome (SUNDS), a typical presentation in individuals from Southeast Asia. Other conduction defects can include first-degree AV block, intraventricular conduction delay, right bundle branch block, and sick sinus syndrome.

Professional guidelines

PubMed

Argenziano M, Antzelevitch C
Expert Rev Cardiovasc Ther 2018 Jun;16(6):387-404. Epub 2018 May 18 doi: 10.1080/14779072.2018.1475230. PMID: 29757020Free PMC Article
Lévy S, Sbragia P
J Interv Card Electrophysiol 2011 Dec;32(3):181-6. Epub 2011 Jul 21 doi: 10.1007/s10840-011-9597-6. PMID: 21833514
Riera AR, Uchida AH, Schapachnik E, Dubner S, Zhang L, Celso Ferreira Filho, Ferreira C
Cardiol J 2008;15(1):4-16. PMID: 18651379

Recent clinical studies

Etiology

Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Antzelevitch C, Yan GX
Heart Rhythm 2015 Aug;12(8):1852-66. Epub 2015 Apr 11 doi: 10.1016/j.hrthm.2015.04.014. PMID: 25869754Free PMC Article
Li GL, Yang L, Cui CC, Sun CF, Yan GX
Chin Med J (Engl) 2015 Apr 5;128(7):969-75. doi: 10.4103/0366-6999.154320. PMID: 25836620Free PMC Article
Sethi KK, Sethi K, Chutani SK
Indian Heart J 2014 Jul-Aug;66(4):443-52. Epub 2014 Aug 5 doi: 10.1016/j.ihj.2014.06.002. PMID: 25173204Free PMC Article
Antzelevitch C, Yan GX
Heart Rhythm 2010 Apr;7(4):549-58. Epub 2009 Dec 11 doi: 10.1016/j.hrthm.2009.12.006. PMID: 20153265Free PMC Article

Diagnosis

Miles C, Boukens BJ, Scrocco C, Wilde AAM, Nademanee K, Haissaguerre M, Coronel R, Behr ER
Circulation 2023 May 23;147(21):1622-1633. Epub 2023 May 22 doi: 10.1161/CIRCULATIONAHA.122.061924. PMID: 37216437Free PMC Article
Antzelevitch C, Di Diego JM
Trends Cardiovasc Med 2022 Aug;32(6):350-363. Epub 2021 Jul 10 doi: 10.1016/j.tcm.2021.07.001. PMID: 34256120Free PMC Article
Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Froelicher V, Wagner G
J Electrocardiol 2013 Sep-Oct;46(5):381-2. doi: 10.1016/j.jelectrocard.2013.06.030. PMID: 23981303
Antzelevitch C, Yan GX
Heart Rhythm 2010 Apr;7(4):549-58. Epub 2009 Dec 11 doi: 10.1016/j.hrthm.2009.12.006. PMID: 20153265Free PMC Article

Therapy

Aizawa Y, Ohashi N, Kawamura A, Ogawa S, Aizawa Y
Pacing Clin Electrophysiol 2023 Aug;46(8):868-874. Epub 2023 Jul 18 doi: 10.1111/pace.14787. PMID: 37461879
Crotti L, Odening KE, Sanguinetti MC
Cardiovasc Res 2020 Jul 15;116(9):1542-1556. doi: 10.1093/cvr/cvaa068. PMID: 32227190
Argenziano M, Antzelevitch C
Expert Rev Cardiovasc Ther 2018 Jun;16(6):387-404. Epub 2018 May 18 doi: 10.1080/14779072.2018.1475230. PMID: 29757020Free PMC Article
Huikuri HV, Juhani Junttila M
Trends Cardiovasc Med 2015 Jan;25(1):24-30. Epub 2014 Sep 6 doi: 10.1016/j.tcm.2014.08.008. PMID: 25442737
Shen MJ, Zipes DP
Circ Res 2014 Mar 14;114(6):1004-21. doi: 10.1161/CIRCRESAHA.113.302549. PMID: 24625726

Prognosis

Crotti L, Odening KE, Sanguinetti MC
Cardiovasc Res 2020 Jul 15;116(9):1542-1556. doi: 10.1093/cvr/cvaa068. PMID: 32227190
Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Omar HR
Herz 2016 Feb;41(1):48-56. Epub 2015 Aug 14 doi: 10.1007/s00059-015-4338-8. PMID: 26272271
Pelliccia A, Quattrini FM
J Electrocardiol 2015 May-Jun;48(3):385-9. Epub 2015 Mar 12 doi: 10.1016/j.jelectrocard.2015.03.012. PMID: 25796101
Antzelevitch C
Ann N Y Acad Sci 2005 Jun;1047:314-23. doi: 10.1196/annals.1341.028. PMID: 16093507Free PMC Article

Clinical prediction guides

Morita H, Ueoka A, Mizuno T, Masuda T, Asada S, Ejiri K, Miyamoto M, Kawada S, Nakagawa K, Nishii N, Yuasa S
Heart Rhythm 2024 May;21(5):562-570. Epub 2024 Jan 17 doi: 10.1016/j.hrthm.2024.01.016. PMID: 38242221
Aizawa Y, Ohashi N, Kawamura A, Ogawa S, Aizawa Y
Pacing Clin Electrophysiol 2023 Aug;46(8):868-874. Epub 2023 Jul 18 doi: 10.1111/pace.14787. PMID: 37461879
Kamakura T, Shinohara T, Yodogawa K, Murakoshi N, Morita H, Takahashi N, Inden Y, Shimizu W, Nogami A, Horie M, Aiba T, Kusano K
Heart 2020 Feb;106(4):299-306. Epub 2019 Aug 7 doi: 10.1136/heartjnl-2019-315007. PMID: 31391205
Omar HR
Herz 2016 Feb;41(1):48-56. Epub 2015 Aug 14 doi: 10.1007/s00059-015-4338-8. PMID: 26272271
Junttila MJ, Sager SJ, Tikkanen JT, Anttonen O, Huikuri HV, Myerburg RJ
Eur Heart J 2012 Nov;33(21):2639-43. Epub 2012 May 29 doi: 10.1093/eurheartj/ehs110. PMID: 22645193

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